The neural substrates of religious experience

Journal of Neuropsychiatry and Clinical Neurosciences

Volumn 9, Issue 3, 1997, Pages 498-510

  Saver, Jeffrey L ^a   Rabin, John ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DELUSION; DEPERSONALIZATION; DEPRESSION; EUPHORIA; EXPERIENCE; HUMAN; LIMBIC SYSTEM; MANIA; MOOD; NEUROBIOLOGY; PRIORITY JOURNAL; RELIGION; REVIEW; SCHIZOPHRENIA;

EID: 0030857215     PISSN: 08950172     EISSN: None     Source Type: Journal    
DOI: 10.1176/jnp.9.3.498     Document Type: Review

References (145)

1. James W: Religion and neurology, in The Varieties of Religious Experience. New York, Longmans, Green and Co, 1902
2. Mackay DM: International biologists' attitudes toward science and religion project (oral interview archive). Los Angeles, CA, UCLA-Reed Neurologic Research Center, October 1981
3. Ross ED, Homan RW, Buck R. Differential hemispheric specialization of primary and social emotions. Neuropsychiatry, Neuropsychology, and Behavioral Neurology 1994; 7:1-19
4. Heilman KM, Bowers D, Valenstein E: Emotional disorders associated with neurological diseases, in Clinical Neuropsychology, 3rd edition, edited by Heilman KM, Valenstein E. New York, Oxford University Press, 1993, pp 461-498
5. Miller DA: Neuropsychology and the emotional component of religion. Pastoral Psychology 1995; 33:267-272
6. Feuerbach L: Lectures on the Essence of Religion (1851), translated by Mannheim R. New York, Harper and Row, 1967
7. James W: The reality of the unseen, in The Varieties of Religious Experience. New York, Longmans, Green and Co, 1902
8. Hay D: "The biology of god": What is the current status of Hardy's hypothesis? International Journal for the Psychology of Religion 1994; 4:1-23
9. Gendlin E: Experiencing and the Creation of Meaning. Glencoe, IL, Free Press, 1962
10. Hardy A: The Biology of God. New York, Taplinger, 1975
11. Hay D: Religious Experience Today: Studying the Facts. London, Mowbray, 1990
12. Tamminen K: Religious experiences in childhood and adolescence: a viewpoint of religious development between the ages of 7 and 20. International Journal for the Psychology of Religion 1994; 4:61-85
13. Wach J: Types of Religious Experience. Chicago, University of Chicago Press, 1951, pp 30-47
14. Stace WT: Mysticism and Philosophy. New York, Macmillan, 1960
15. Carmody DL, Carmody JY: Mysticism. New York, Oxford University Press, 1996
16. Hardy A: The Spiritual Nature of Man. Oxford, Clarendon Press, 1979
17. Waller NG, Kojetin BA, Bouchard TJ, et al: Genetic and environmental influences on religious interests, attitudes, and values: a study of twins reared apart and together. Psychol Sci 1990; 1:138-142
18. Hippocrates: The Genuine Works of Hippocrates. London, Sydenham Society, 1846, pp 843-858
19. Taxil J: Traicté de l'épilepsie [Treatise on epilepsy]. Tournon, 1602
20. Esquirol JED: Des maladies mentales [On mental illness]. Paris, Balliere, 1838
21. Morel BA: Traité des maladies mentales [Treatise on mental illness]. Paris, Masson, 1860
22. Howden JC: The religious sentiments in epileptics. J Ment Sci 1872/1873; 18:491-497
23. Spratling WP: Epilepsy and Its Treatment. Philadelphia, WB Saunders, 1904
24. Turner WA: Epilepsy. London, Macmillan, 1907
25. Spilka B, Schmidt G: General attribution theory for the psychology of religion: the influence of event-character on attributions to God. Journal for the Scientific Study of Religion 1983; 22:326-339
26. Schachter S, Singer JE: Cognitive, social, and physiological determinants of emotional states. Psychol Rev 1962; 69:379-399
27. Palmini A, Gloor P: The localizing value of auras in partial seizures: a prospective and retrospective study. Neurology 1992; 42:801-806
28. So NK: Epileptic auras, in The Treatment of Epilepsy: Principles and Practice, edited by Wyllie E. Philadelphia, Lea and Febiger, 1993, pp 369-377
29. Mendez MF, Cherrier MM, Perryman KM: Epileptic forced thinking from left frontal lesions. Neurology 1996; 47:79-83
30. Jackson JH, Stewart JP: Epileptic attacks with a warning of a crude sensation of smell and with the intellectual aura (dreamy state) in a patient who had symptoms pointing to a gross organic disease of the right temporo-sphenoidal lobe. Brain 1899; 22:534-549
31. Devinsky O, Luciano D: Psychic phenomena in partial seizures. Semin Neurol 1991; 11:100-109
32. Mendez MF, Engebrit B, Doss R, et al: The relationship of epileptic auras and psychological attributes. J Neuropsychiatry Clin Neurosci 1996; 8:287-292
33. Gloor P: Experiential phenomena of temporal lobe epilepsy. Brain 1990; 113:1673-1694
34. Fish DR, Gloor P, Quesney FL, et al: Clinical responses to electrical brain stimulation of the temporal and frontal lobes in patients with epilepsy. Brain 1993; 116:397-414
35. Weil AA: Ictal emotions occurring in temporal lobe dysfunction. Arch Neurol 1959; 1:87-97
36. Penfield W, Jasper H: Epilepsy and the Functional Anatomy of the Human Brain. Boston, Little, Brown, 1954
37. Gloor P, Olivier A, Quesney LF, et al: The role of the limbic system in experiential phenomena of temporal lobe epilepsy. Ann Neurol 1982; 23:129-144
38. Hécaen H, de Ajuriaguerra J: Méconnaissances et hallucinations corporelles [Somatic delusions and hallucinations]. Paris, Masson, 1952
39. DeningTR, Berrios GE: Autoscopic phenomena. Br J Psychiatry 1994; 165:808-817
40. Devinsky O, Feldmann E, Burrowes K, et al: Autoscopic phenomena with seizures. Arch Neurol 1989; 46:1080-1088
41. Voskuil PHA: The epilepsy of Fyodor Mikhailovitch Dostoevsky (1821-1881). Epilepsia 1983; 24:658-667
42. Gastaut H: New comments on the epilepsy of Fyodor Dostoevsky. Epilepsia 1984; 25:408-411
43. Geschwind N: Dostoievsky's epilepsy, in Psychiatric Aspects of Epilepsy, edited by Blumer D. Washington, DC, American Psychiatric Press, 1984, pp 325-334
44. Williams D: The structure of emotions reflecting in epileptic experiences. Brain 1956; 79:29-67
45. Devinsky O, Feldmann E, Bromfield E, et al: Structured interview for simple partial seizures: clinical phenomenology and diagnosis. Journal of Epilepsy 1991; 4:107-116
46. Stevens JR, Mark VH, Ervin F, et al: Deep temporal stimulation in man. Arch Neurol 1969; 21:157-169
47. Obrador S, Delgado JMR, Martin-Rodriguez JG: Emotion areas of the human brain and their therapeutic stimulation, in Cerebral Localization, edited by Zulch KJ. Berlin, Springer, 1973, pp 171-183
48. Mandell AJ: Toward a psychobiology of transcendence: God in the brain, in The Psychobiology of Consciousness, edited by Davidson JM, Davidson RJ. New York, Plenum, 1980, pp 379-464
49. Williams D: The structure of emotions reflected in epileptic experience. Brain 1956; 79:29-67
50. Morgan H: Dostoyevsky's epilepsy: a case report and comparison. Surg Neurol 1990; 33:413-416
51. Cirignotta F, Todesco CV, Lugaresi E: Temporal epilepsy with ecstatic seizures (so-called Dostoyevsky epilepsy). Epilepsia 1980; 21:705-710
52. Naito H, Matsui N: Temporal lobe epilepsy with ictal ecstatic state and interictal behavior of hypergraphia. J Nerv Ment Dis 1988; 176:123-124
53. Dewhurst K, Beard AW: Sudden religious conversions in temporal lobe epilepsy. Br J Psychiatry 1970; 117:497-507
54. Logsdail SJ, Toone BK: Post-ictal psychoses. Br J Psychiatry 1988; 152:246-252
55. Savard G, Andermann F, Olivier A, et al: Postictal psychosis after complex partial seizures: a multiple case study. Epilepsia 1991; 32:225-231
56. Kanemoto K, Kawasaki J, Kawai I: Postictal psychosis: a comparison with acute interictal and chronic psychoses. Epilepsia 1996; 37:551-556
57. Waxman SG, Geschwind N: The interictal behavior syndrome of temporal lobe epilepsy. Arch Gen Psychiatry 1975; 32:1580-1586
58. Bear DM, Fedio P: Quantitative analysis of interictal behavior in temporal lobe epilepsy. Arch Neurol 1977; 34:454-467
59. Bear D, Levin K, Blumer D, et al: Interictal behaviour in hospitalised temporal lobe epileptics: relationship to idiopathic psychiatric syndromes. J Neurol Neurosurg Psychiatry 1982; 45:481-488
60. Bear DM: Temporal lobe epilepsy: a syndrome of sensory-limbic hyperconnection. Cortex 1979; 15:357-384
61. Gastaut H, Morin G, Leserve N: Étude du comportement des épileptiques psychomoteurs dans l'intervalle de leurs crises [Study of the interictal behavior of psychomotor epileptics]. Annales Medico-Psychologiques 1955; 113:1-27
62. Adamec RE: Partial kindling of the ventral hippocampus: identification of changes in limbic physiology which accompany changes in feline aggression and defense. Physiol Behav 1991; 49:443-453
63. Griffith N, Engel J, Bandler R: Ictal and enduring interictal disturbances in emotional behaviour in an animal model of temporal lobe epilepsy. Brain Res 1987; 400:360-364
64. Engel J, Bandler R, Griffith NC, et al: Neurobiological evidence for epilepsy-induced interictal disturbances. Adv Neurol 1991; 55:97-111
65. Willmore LJ, Heilman KM, Fennell E: Effect of chronic seizures on religiosity. Transactions of the American Neurological Association 1980; 105:85-87
66. Sensky T, Wilson A, Petty R, et al: The interictal personality traits of temporal lobe epileptics: religious belief and its association with reported mystical experiences, in Advances in Epileptology, edited by Porter R. New York, Raven, 1984, pp 545-549
67. Tucker DM, Novelly RA, Walker PJ: Hyperreligiosity in temporal lobe epilepsy: redefining the relationship. J Nerv Ment Dis 1987; 175:181-184
68. Roberts JKA, Guberman A: Religion and epilepsy. Psychiatric Journal of the University of Ottawa 1989; 14:282-286
69. Heim A: Remarks on fatal falls. Yearbook of the Swiss Alpine Club 1892; 27:327-337
70. Noyes R, Kletti R: Depersonalization in the face of life-threatening danger: a description. Psychiatry 1976; 39:19-27
71. Rodin E: The reality of death experience: a personal perspective. J Nerv Ment Dis 1980; 168:259-263
72. Owens JE, Cook EW, Stevenson I: Features of "near-death experience" in relation to whether or not patients were near death. Lancet 1990; 336:1175-1177
73. Greyson B, Bush NE: Distressing near-death experiences. Psychiatry 1992; 55:95-110
74. Stevenson I, Cook EW: Involuntary memories during severe physical illness or injury. J Nerv Ment Dis 1995; 183:452-458
75. Kellehear A: Culture, biology, and the near-death experience. J Nerv Ment Dis 1993; 181:148-156
76. Carr DB: Endorphins at the approach of death (letter). Lancet 1981; 1:390
77. Sotelo J, Perez R, Guevara P, et al: Changes in brain, plasma, and cerebrospinal fluid contents of beta-endorphin in dogs at the moment of death. Neurol Res 1995; 17:223-225
78. Kuhar MJ, Pert CB, Snyder SH: Regional distribution of opiate receptor binding in monkey and human brain. Nature 1973; 245:447-450
79. Henriksen S, Bloom F, McCoy F, et al: Beta-endorphin induces nonconvulsive limbic seizures. Proc Natl Acad Sci USA 1978; 75:5221-5225
80. Ableitner A, Schulz R: Neuroanatomical sites mediating the central actions of beta-endorphin as mapped by changes in glucose utilization: involvement of mu opioid receptors. J Pharmacol Exp Ther 1992; 262:415-423
81. Jansen K: Neuroscience, ketamine, and the near-death experience, in The Near-Death Experience Reader, edited by Bailey LW, Yates J. New York, Routledge, 1996, pp 265-282
82. Strassman RJ: Hallucinogenic drugs in psychiatric research and treatment. J Nerv Ment Dis 1995; 183:127-138
83. Strassman RJ, Quails CR, Uhlenhuth EH, et al: Dose-response study of N,N-dimethyltryptamine in humans. Arch Gen Psychiatry 1994; 41:98-108
84. LaBarre W: The Peyote Cult, 5th edition. Norman, OK, University of Oklahoma Press, 1989
85. Pahnke WN: An analysis of the relationship between psychedelic drugs and the mystical consciousness. Doctoral dissertation, Harvard University, 1963
86. Doblin R: Pahnke's "Good Friday Experiment": a long-term follow-up and methodological critique. J Transpers Psychol 1991; 23:1-28
87. Masters REL, Houston J: The Varieties of Psychedelic Experience. New York, Holt, Rinehart, and Winston, 1966
88. Joyce JN, Share A, Lexow N, et al: Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics. Neuropsychopharmacology 1993; 8:315-336
89. Serafetinides EA: The significance of the temporal lobes and of hemisphere dominance in the production of the LSD-25 symptomatology in man. Neuropsychologia 1965; 95:53-63
90. Heise DR: Delusions and the construction of reality, in Delusional Beliefs, edited by Oltmanns TF, Maher BA. New York, Wiley, 1988, pp 259-272
91. Greenberg D, Witzum E, Buchbinder JT: Mysticism and psychosis: the fate of Ben Zoma. Br J Med Psychol 1992; 65:223-235
92. Barnhouse RT: How to evaluate patients' religious ideation, in Psychiatry and Religion: Overlapping Concerns, edited by Robinson LH. Washington, DC, American Psychiatric Press, 1986, pp 89-106
93. Gaines A: Delusions: culture, psychosis, and the problem of meaning, in Delusional Beliefs, edited by Oltmanns TF, Maher BA. New York, Wiley, 1988, pp 230-258
94. Winters KC, Neale JM: Delusions and delusional thinking in psychotics: a review of the literature. Clin Psychol Rev 1983; 3:227-253
95. Cutting J: Descriptive psychopathology, in Schizophrenia, edited by Hirsch SR, Weinberger DR. Cambridge, MA, Blackwell Science, 1995, pp 15-27
96. World Health Organization: Schizophrenia: An International Follow-up Study. New York, Wiley, 1979
97. Wing JK, Cooper JE, Sartorius N: The Description and Classification of Psychiatric Symptoms: An Instruction Manual for the PSE and CATEGO system. Cambridge, England, Cambridge University Press, 1974
98. Westermeyer J: Some cross-cultural aspects of delusions, in Delusional Beliefs, edited by Oltmanns TF, Maher BA. New York, Wiley, 1988, pp 212-229
99. Klaf FS, Hamilton JG: Schizophrenia: a hundred years ago and today. Journal of Mental Science 1961; 107:819-827
100. Garety PA, Hemsley DR: Delusions: Investigations Into the Psychology of Delusional Reasoning. New York, Oxford University Press, 1994
101. Bentall RP: The syndromes and symptoms of psychosis, in Reconstructing Schizophrenia, edited by Bentall RP. London, Routledge, 1990, pp 23-60
102. Maher BA, Spitzer M: Delusions, in Comprehensive Handbook of Psychopathology, 2nd edition, edited by Sutker P, Adams H. New York, Plenum, 1993, pp 263-293
103. Von Damurus E: The specific laws of logic in schizophrenia, in Language and Thought in Schizophrenia, edited by Kasanin JS. Berkeley, CA, University of California Press, 1944, pp 30-44
104. Hemsley DR, Garety PA: The formation and maintenance of delusions: a Bayesian analysis. Br J Psychiatry 1986; 149:51-56
105. Wiggins OP, Schwartz MA, Northoff G: Toward a Husserlian phenomenology of the initial stages of schizophrenia, in Philosophy and Psychopathology, edited by Spitzer M, Maher BA. New York, Springer-Verlag, 1990, pp 21-34
106. Benson DF, Stuss DT: Frontal lobe influences on delusions: a clinical perspective. Schizophr Bull 1990; 16:403-411
107. Cutting J: The phenomenology of acute organic psychosis: comparison with acute schizophrenia. Br J Psychiatry 1987; 151:324-332
108. Carlson GA, Goodwin FK: The stages of mania: a longitudinal analysis of the manic episode. Arch Gen Psychiatry 1973; 28:221-228
109. World Health Organization: The International Pilot Study of Schizophrenia. Geneva, WHO, 1973
110. Leff JP, Fischer M, Bertelsen AC: A cross-national epidemiological study of mania. Br J Psychiatry 1976; 129:428-442
111. Petry S, Cummings JL, Hill MA, et al: Personality alterations in dementia of the Alzheimer type. Arch Neurol 1988; 45:1187-1190
112. Chatterjee A, Strauss ME, Smyth KA, et al: Personality changes in Alzheimer disease. Arch Neurol 1992; 49:486-491
113. Cummings JL: Organic delusions: phenomenology, anatomical correlations, and review. Br J Psychiatry 1985; 146:184-197
114. Lynch T, Sano M, Marder KS, et al: Clinical characteristics of a family with chromosome 17-linked disinhibition-dementia-parkinsonism-amyotrophy complex. Neurology 1994; 44:1878-1884
115. Davidson RJ: Anterior cerebral asymmetry and the nature of emotion. Brain Cogn 1992; 20:125-151
116. James W: The Varieties of Religious Experience. New York, Longmans, Green and Co, 1902
117. Otto R: The Idea of the Holy. New York, Oxford University Press, 1923
118. Byrnes JF: The Psychology of Religion. New York, The Free Press, 1984
119. Brown LB: The Psychology of Religious Belief. London, Academic Press, 1987
120. Clark WH: The phenomena of religious experience, in Religious Experience: Its Nature and Function in the Human Psyche, edited by Clark WH, Malony HN, Daane J, et al. Springfield, IL, Charles C Thomas, 1973, pp 21-40
121. Spika B, Hood RW, Gorsuch RL: The Psychology of Religion: An Empirical Approach. Engelwood Cliffs, NJ, Prentice-Hall, 1985
122. Joseph R: Neuropsychiatry, Neuropsychology, and Clinical Neuroscience, 2nd edition. Baltimore, Williams and Wilkins, 1996
123. Aggleton JP: The contribution of the amygdala to normal and abnormal emotional states. Trends Neurosci 1993; 16:328-333
124. Damasio AR, Tranel D, Damasio H: Somatic markers and the guidance of behavior, in Frontal Lobe Function and Dysfunction, edited by Levin H, Eisenberg H, Benton A. New York, Oxford University Press, 1991, pp 217-228
125. Saver JL, Damasio AR: Preserved access and processing of social knowledge in a patient with acquired sociopathy due to ventromedial frontal damage. Neuropsychologia 1991; 29:1241-1249
126. Jaynes J: The Origin of Consciousness in the Breakdown of the Bicameral Mind. Boston, Houghton Mifflin, 1976
127. Lex BW: The neurobiology of ritual trance, in The Spectrum of Ritual, edited by D'Aquili EG, Laughlin CD, Mcmanus J. New York, Columbia University Press, 1979, pp 117-151
128. Ashbrook JB: The Brain and Belief: Faith in the Light of Brain Research. Bristol, IN, Wyndham Hall Press, 1988
129. Persinger MA: Vectorial cerebral hemisphericity as differential sources for the sensed presence, mystical experiences, and religious conversions. Percept Mot Skills 1993; 76:915-930
130. D'Aquili E: The myth-ritual complex, a biogenetic structural analysis, in Brain, Culture, and the Human Spirit, edited by Asbrook JB. Lanham, MD, University Press of America, 1993, pp 45-75
131. Turner V: Body, brain, and culture, in Brain, Culture, and the Human Spirit, edited by Asbrook JB. Lanham, MD, University Press of America, 1993, pp 77-108
132. Wulff DM: Psychology of Religion, 2nd edition. New York, Wiley, 1996
133. Landsborough D: St. Paul and temporal lobe epilepsy. J Neurol Neurosurg Psychiatry 1987; 50:659-664
134. Vercelletto P: La maladie de Saint Paul. Rev Neurol 1994; 150:835-839
135. Trimble MR: The Psychoses of Epilepsy. New York, Raven, 1991
136. Temkin O: The Falling Sickness: A History of Epilepsy From the Greeks to the Beginning of Modern Neurology. Baltimore, Johns Hopkins University Press, 1971
137. Drucker T: Malaise of Margery Kempe. New York State Journal of Medicine 1972; 72:2911-2917
138. Foote-Smith E, Bayne L: Joan of Arc. Epilepsia 1991; 32:810-815
139. Johnson J: Henry Maudslay on Swedenborg's messianic psychosis. Br J Psychiatry 1994; 165:690-691
140. Foote-Smith E, Smith TJ: Emanuel Swedenborg. Epilepsia 1996; 37:211-218
141. Taylor DC, Marsh SM: Hughlings Jackson's Dr Z: the paradigm of temporal lobe epilepsy revealed. J Neurol Neurosurg Psychiatry 1980; 43:758-767
142. Arenberg IK, Countryman LLF, Bernstein LH, et al: Vincent's violent vertigo. Acta Otolaryngol 1991; 485:84-103
143. Buckley P: Mystical experience and schizophrenia. Schizophr Bull 1981; 7:516-521
144. Oxman TE, Rosenberg SD, Schnurr PP, et al: The language of altered states. J Nerv Ment Dis 1988; 176; 401-408
145. Group for the Advancement of Psychiatry: Mysticism: Spiritual Quest or Psychic Disorder? (Mental Health Materials Center, vol 9, publ no 97). New York, Mental Health Materials Center, 1976