Ascorbate as a substrate for glycolysis or gluconeogenesis: Evidence for an interorgan ascorbate cycle

Free Radical Biology and Medicine

Volumn 23, Issue 5, 1997, Pages 804-808

  Braun, Lászlóo ^a   Puskás, Ferenc ^a   Csala, Miklós ^a   Mészáros, György ^a   Mandl, József ^a   Bánhegyi, Gábor ^a  

^a SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

Author keywords

Ascorbic acid; Dehydroascorbic acid; Erythrocytes; Free radicals; Glycolysis; Lactate; Pentose phosphate pathway

Indexed keywords

ASCORBIC ACID; DEHYDROASCORBIC ACID; GULONOLACTONE OXIDASE;

ANIMAL CELL; ARTICLE; CATABOLISM; CONTROLLED STUDY; ENZYME ACTIVITY; ERYTHROCYTE; GLUCONEOGENESIS; GLYCOLYSIS; NONHUMAN; PENTOSE PHOSPHATE CYCLE; PRIORITY JOURNAL;

ANIMALS; ASCORBIC ACID; DEHYDROASCORBIC ACID; ERYTHROCYTES; GLUCOSE; GLYCOLYSIS; HUMANS; LACTIC ACID; MALE; MICE; OXYTHIAMINE; TRANSKETOLASE; TUMOR CELLS, CULTURED; VITAMIN K;

ANIMALIA; MURINAE;

EID: 0030857089     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(97)00022-1     Document Type: Article

References (14)

1. Levine M. New concepts in the biology and biochemistry of ascorbic acid. N. Engl. J. Med. 314:1986;892-902.
2. Rose R. C., Bode A. M. Biology of free radical scavangers: An evaluation of ascorbate. FASEB J. 7:1993;1135-1142.
3. Meister A. Glutathione-ascorbic acid antioxidant system in animals. J. Biol. Chem. 269:1994;9397-9400.
4. Winkler B. S., Orselli S. M., Rex T. S. The redox couple between glutathione and ascorbic acid: A chemical and physiological perspective. Free Radic. Biol. Med. 17:1994;333-349.
5. Nishikimi M., Fukuyama R., Minoshima S., Shimizu N., Yagi K. Cloning and chromosomal mapping of the human nonfunctional gene for L-gulono- γ -lactone oxidase, the enzyme for L-ascorbic acid biosynthesis missing in man. J. Biol. Chem. 269:1994;13685-13688.
6. Chatterjee I. B. Evolution and the biosynthesis of ascorbic acid. Science. 182:1973;1271-1272.
7. Braun L., Puskás F., Csala M., Györffy E., Garzó T., Mandl J., Bánhegyi G. Gluconeogenesis from ascorbic acid: Ascorbate recycling in isolated murine hepatocytes. FEBS Lett. 390:1996;183-186.
8. Searcy R. L. Diagnostic biochemistry. 1969;460-464 McGraw Hill, New York.
9. Marbach E. P., Weil M. H. Rapid enzymatic measurement of blood lactate and pyruvate. Clin. Chem. 13:1967;314.
10. Harapanhalli R. S., Howell R. W., Rao D. V. Testicular and plasma ascorbic acid levels in mice following dietary intake: A high performance liquid chromatographic analysis. J. Chromatogr. 614:1993;233-243.
11. Oshinsky R. J., Wang Y. M., van Eys J. Xylitol infusion and oxalate formation in rabbits. J. Nutr. 107:1977;792-804.
12. Tolbert B. M., Downing M., Carlson R. W., Knight M. K., Baker E. M. Chemistry and metabolism of ascorbic acid and ascorbate sulfate. Ann. NY Acad. Sci. 258:1975;48-69.
13. Leeuwenburgh C., Ji L. L. Glutathione depletion in rested and exercised mice: Biochemical consequence and adaptation. Arch. Biochem. Biophys. 316:1995;941-949.
14. Goldenberg H., Schweinzer E. Transport of vitamin C in animal and human cells. J. Bioenerg. Biomembr. 26:1994;359-367.