Influence of hepatitis C virus (HCV) viraemia upon serum aminotransferase activity in chronic dialysis patients

Nephrology Dialysis Transplantation

Volumn 12, Issue 7, 1997, Pages 1394-1398

  Fabrizi, F ^a,f   Lunghi, G ^b   Andrulli, S ^a   Pagliari, B ^c   Mangano, S ^d   Faranna, P ^e   Pagano, A ^b   Locatelli, F ^a  

^a Hospital   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c Dialysis Unit of Sondrio   (Italy)

^d Dialysis Unit of Tradate   (Italy)

^e Trescore Balneario Hospitals ^*  (Italy)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aminotransferase levels; Dialysis; HCV genotype; HCV viraemia; Hepatitis C virus

Indexed keywords

ALANINE AMINOTRANSFERASE; AMINOTRANSFERASE; HEPATITIS C ANTIBODY; LIVER ENZYME; VIRUS RNA;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; COVARIANCE; FEMALE; GENDER; GENOTYPE; HEMODIALYSIS PATIENT; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; NONHUMAN; PRIORITY JOURNAL; REGRESSION ANALYSIS; VIREMIA;

ADULT; AGED; AGED, 80 AND OVER; ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; FEMALE; GENOTYPE; HEPACIVIRUS; HEPATITIS C; HUMANS; MALE; MIDDLE AGED; RENAL DIALYSIS; VIREMIA;

EID: 0030857001     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/12.7.1394     Document Type: Article

References (46)

1. Hardy NM, Sandroni S, Danielson S, Wilson DJ. Antibody to hepatitis C virus increases with time on hemodialysis. Clin Nephrol 1992; 38: 44-48
2. Mondelli MU, Smedile V, Piazza V et al. Abnormal alanine aminotransferase activity reflects exposure to hepatitis C virus in hemodialysis patients. Nephrol Dial Transplant 1991; 6: 480-483
3. Almroth G, Ekermo B, Franzen L, Hed J. Antibody response to hepatitis C virus and its modes of transmission in dialysis patients. Nephron 1991; 59: 232-235
4. Jeffers LJ, Perez GO, De Medina MD et al. Hepatitis C infection in two urban hemodialysis units. Kidney Int 1990; 38: 320-322
5. Lin HH, Huang CC, Sheen IS, Lin DY, Liaw YF. Prevalence of antibodies to hepatitis C virus in the hemodialysis unit. Am J Nephrol 1991; 11: 192-194
6. Fabrizi F, Raffaele L, Bacchini G et al. Antibodies to hepatitis C virus (HCV) and transaminase concentration in chronic hemodialysis patients: a study with second-generation assays. Nephrol Dial Transplant 1993; 8: 744-747
7. Carrera F, Silva JG, Oliveira C, Frazao JM, Pires C. Persistence of antibodies to hepatitis C virus in a chronic hemodialysis population. Nephron 1994; 68: 38-40
8. Knudsen F, Wantzin P, Rasmussen K et al. Hepatitis C in dialysis patients: relationship to blood transfusions, dialysis and liver disease. Kidney Int 1993; 43: 1353-1356
9. Oliva JA, Maymo RM, Carrio J, Delgado O, Mallafre JM. Late seroconversion of C virus markers in hemodialysis patients. Kidney Int 1993; 43[S 41]: S153-S156
10. Hayashi J, Nakashima K, Kaijama W et al. Prevalence of antibody to hepatitis C virus in hemodialysis patients. J Epidemiol 1991; 134: 651-657
11. Chen KS, Lo KS, Lee N, Leu ML, Huang CC, Fang KM. Superinfection with hepatitis C virus in hemodialysis patients with hepatitis B surface antigenemia: its prevalence and clinical significance in Taiwan. Nephron 1996; 73: 158-164
12. Sakamoto N, Enomoto N, Marumo F, Sato C. Prevalence of hepatitis C virus infection among long-term hemodialysis patients: detection of hepatitis C virus RNA in plasma. J Med Virol 1993; 39: 11-15
13. Chan TM, Lok ASF, Cheng IKP, Chan RT. Prevalence of hepatitis C virus infection in hemodialysis patients: a longitudinal study comparing the results of RNA and antibody assays. Hepatology 1993; 17: 5-8
14. Sheu JC, Lee SH, Wang JT, Shih LN, Wang TH, Chen DS. Prevalence of anti-HCV and HCV viremia in hemodialysis patients in Taiwan. J Med Virol 1992; 37: 108-112
15. Yuki N, Hayashi N, Matsushita Y et al. Hepatitis C biochemical remission and viral replication in haemodialysis patients. J Med Virol 1996; 48: 242-246
16. Oguchi H, Miyasaka H, Tokunaga S et al. Hepatitis virus infection (HBV and HCV) in chronic Japanese hemodialysis units. Clin Nephrol 1992; 38: 36-43
17. Bukh J, Wantzin P, Krogsgaard K, Knudsen K, Purcell RH, Miller RH. High prevalence of hepatitis C virus (HCV) RNA in dialysis patients: failure of commercially available antibody tests to identify a significant number of patients with HCV infection. J Infect Dis 1993; 168: 1343-1348
18. Fernandez JL, del Pino N, Lef L et al. Serum hepatitis C virus RNA in anti-HCV negative hemodialysis patients. Dial Transplant 1996; 25: 14-18
19. Wolf PL, Williams D, Coplon N, Coulson AS. Low aspartate aminotransferase activity in serum of patients undergoing chronic hemodialysis. Clin Chem 1972; 18: 567-568
20. Warnock LG, Stone WJ, Wagner C. Decreased aspartate aminotransferase ('SGOT') activity in serum of uremic patients. Clin Chem 1974; 20: 1213-1216
21. Cohen GA, Goffinet JA, Donabedian RK, Conn HO. Observations on decreased serum glutamic oxaloacetic transaminase (SGOT) activity in azotemic patients. Ann Intern Med 1976; 84: 275-280
22. Guh JY, Lai YH, Yang CY et al. Impact of decreased serum transaminase levels on the evaluation of viral hepatitis in hemodialysis patients. Nephron 1995; 69: 459-465
23. Nanji AA. Decreased activity of commonly measured enzymes: cause and clinical significance. Am J Med Technol 1983; 49: 241-245
24. Natov SN, Pereira BJG. Hepatitis C infection in patients on dialysis. Semin Dial 1994; 5: 360-368
25. Davis LC, Gretch DR, Carithers RL. Hepatitis C virus in renal disease. Curr Opin Nephrol Hypertens 1994; 3: 164-173
26. Roth D. Hepatitis C virus: the nephrologist's view. Am J Kidney Dis 1995; 25: 3-16
27. Dodd RY, Popovsky MA, and Members of the Scientific Section Coordinating Committee. Antibodies to hepatitis core antigen and the infectivity of the blood supply. Transfusion 1991; 31: 443-449
28. Sherman KE. Alanine aminotransferase in clinical practice. Arch Intern Med 1991; 151: 260-265
29. Cahen DL, Van Leeuwen DJ, ten Kate FJW, Blok APR, Oosting J, Chamuleau RAFM. Do serum ALAT values reflect the inflammatory activity in the liver of patients with chronic viral hepatitis? Liver 1996; 16: 105-109
30. van der Poel CL, Cuypers HT, Reesink HW et al. Confirmation of hepatitis C virus infection by new four-antigen recombinant immunoblot assay. Lancet 1991; 337: 317-319
31. Prati D, Capelli C, Bosoni P, Mozzi F, Zanella A, Sirchia G. Determination of hepatitis C virus RNA in the serum by the Amplicor HCV PCR kit. Vox Sang 1994; 67: 112-114
32. van Doom LJ, Kleter B, Stuyver L et al. Analysis of hepatitis C virus genotypes by a line probe assay and correlation with antibody profiles. J Hepatol 1994; 21: 122-129
33. Simmonds P, Alberti A, Alter HJ et al. A proposed system for nomenclature of hepatitis C viral genomes. Hepatology 1994; 19: 1321-1324
34. Fabrizi F, Marcelli D, Bacchini G, Guarnori I, Erba G, Locatelli F. Antibodies to hepatitis C virus (HCV) in chronic renal failure (CRF) patients on conservative therapy: prevalence, risk factors and relationship to liver disease. Nephrol Dial Transplant 1994; 9: 780-784
35. Pol S, Romeo R, Zins B et al. Hepatitis C virus RNA in anti-HCV positive hemodialyzed patients: significance and therapeutic implications. Kidney Int 1993; 44: 1097-1100
36. Picciotto A, Varagona G, Gurreri G et al. Anti-hepatitis C virus antibodies and hepatitis C virus viraemia in haemodialysis patients. Nephrol Dial Transplant 1993; 8: 1115-1117
37. Fabrizi F, Lunghi G, Guarnori I et al. Virological characteristics of hepatitis C virus (HCV) infection in chronic hemodialysis patients: a cross-sectional study. Clin Nephrol 1995; 44: 49-55
38. Dussol B, Lamballerie X, Brunet P el al. Is hepatitis C virus-RNA detection by nested polymerase chain reaction clinically relevant in hemodialysis patients? Clin Nephrol 1996; 45: 257-260
39. Caramelo C, Ortiz A, Aguilera B et al. Liver disease patterns in hemodialysis patients with antibodies to hepatitis C virus. Am J Kidney Dis 1993; 22: 822-828
40. Al-Wakeel J, Malik GH, Al-Mohaya S et al. Liver disease in dialysis patients with antibodies to hepatitis C virus. Nephrol Dial Transplant 1996; 11: 2265-2268
41. Moyer LA, Alter MJ. Hepatitis C virus in the hemodialysis setting: a review with recommendation for control. Semin Dial 1994; 7: 124-127
42. DuBois DB, Gretch D, dela Rosa C et al. Quantitation of hepatitis C viral RNA in sera of hemodialysis patients; gender-related differences in viral load. Am J Kidney Dis 1994; 24: 795-801
43. Pozzato G, Kaneko S, Moretti M et al. Different genotypes of hepatitis C virus are associated with different severity of chronic liver disease. J Med Virol 1994; 43: 291-296
44. Kanai K, Kako M, Okamoto H. HCV genotypes in chronic hepatitis C and response to Interferon. Lancet 1992; 339: 1543
45. Dhaliwal SK, Prescott LE, Dow BC et al. Influence of viremia and genotype upon serological reactivity in screening assays for antibody to hepatitis C virus. J Med Virol 1996; 48: 184-190
46. Fabrizi F, Lunghi G, Marai P et al. Virological and histological features of hepatitis C virus (HCV) infection in kidney transplant recipients. Nephrol Dial Transplant 1996; 11: 159-164