Human recombinant anti Rh(D) monoclonal antibodies: Improvement of biological properties by in vitro class-switch

Human Antibodies

Volumn 8, Issue 1, 1997, Pages 17-25

  Klein, Philippe ^a   Béliard, Roland ^a   Glacet, Arnaud ^a   Moitel, Sébastien ^a   Ducrot, Thierry ^a   Bourel, Dominique ^a  

^a Laboratoire d'Ingénierie Cellulaire et Moléculaire   (France)

Author keywords

Anti D; Effector functions; Human monoclonal antibodies; Mammalian expression; Recombinant antibodies; Transfectomas

Indexed keywords

HUMAN MONOCLONAL ANTIBODY; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN HEAVY CHAIN; RHESUS D ANTIBODY;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; GENE REARRANGEMENT; HUMAN; HYBRIDOMA; MYELOMA CELL; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; RECOMBINANT DNA TECHNOLOGY;

EID: 0030856754     PISSN: 10932607     EISSN: None     Source Type: Journal    
DOI: 10.3233/hab-1997-8103     Document Type: Article

References (35)

1. Köhler G, Milstein C. Continuous culture of fused cells secreting antibody of predefined specificity. Nature 1975; 256: 495
2. Schawler DL, Bartholomew RM, Smith LM, Dillman RD. Human immune response to multiple injections of murine monoclonal IgG. J Immunol 1985; 135: 1530
3. Miller RA, Oseroff AR, Stratte PT, Levy R. Monoclonal antibody therapeutic trials in seven patients with T-cell lymphoma. Blood 1983; 62: 988
4. Boyd JE, James K. Human monoclonal antibodies: Their potential, problems, and prospects. Adv Biotechnol Processes 1989; 11: 2
5. Larrick JW, Dyer BJ, Senyk G, Hart SM, Moss R, Lippman D, Jahnsen MC, Wang J, Weintraub H, Raubitschek AA. In vitro expansion of human B cells for the production of human monoclonal antibodies. In Engleman EG, Foung, SKH eds. Human Hybridomas and Monoclonal Antibodies, New York: Plenum 1985: 149
6. Olsson L, Kronstrom H, Cambon-de-Mouzon A, Honsik C, Brodin T, Jacobsen B. Antibody producing human-human hybridomas I Technical Aspects J Immunol Methods 1983; 61: 17
7. Boulianne GL, Hazumi N, Schulman MJ. Production of functional chimaeric mouse-human antibody. Nature 1984; 312: 643
8. Morrison SL, Johnson MJ, Heyenberg LA, Oi VT. Chimeric human antibody molecules: Mouse antigen binding domains with human constant region domains. Proc Natl Acad Sci USA 1984; 81: 6851
9. Jones PT, Dear PH, Foote J, Neuberger MS, Winter G. Replacing the complementarity-determining regions in a human antibody with those from a mouse. Nature 1986; 321: 522
10. Lewis AP, Crowe JS. Immunoglobulin complementarity-determining region grafting by recombinant polymerase chain reaction to generate humanised monoclonal antibodies. Gene 1991; 101: 297
11. Riechmann L, Clark M, Waldmann H, Winter, G. Reshaping human antibodies for therapy. Nature 1988; 332: 323
12. Verhoeyen M, Milstein C, Winter G. Reshaping human antibodies: Grafting an antilysozyme activity. Science 1988; 239: 1534
13. Little M, Breitling F, Dübel S, Fuchs P, Braunagel M. Human antibody libraries in Escherichia coli. J Biotechnol 1995; 41: 187
14. Larrick JW, Danielsson L, Brenner CA, Wallace EF, Abrahamson M, Fry KE, Borrebaeck CAK. Polymerase chain reaction using mixed primers: Cloning of human monoclonal antibody variable region genes from single hybridoma cells. Biotechnology 1989; 7: 934
15. Lewis AP, Parry N, Peakman TC, Crowe JS. Rescue and expression of human immunoglobulin genes to generate functional human monoclonal antibodies. Hum Antibod Hybridomas 1992; 3: 146
16. Ames RS, Tornetta MA, Deen K, Jones CS, Swift AM, Ganguly S. Conversion of murine Fabs isolated from a combinatorial phage display library to full length immunoglobulins. J Immunol Methods 1995; 184: 177
17. Bender E, Woof JM, Atkin JD, Barker MD, Bebbington CR, Burton DR. Recombinant human antibodies: Linkage of a Fab fragment from a combinatorial library to an Fc fragment for expression in mammalian cell culture. Hum Antibod Hybridomas 1993; 4: 74
18. Kearney JG, Radbruch A, Liesegang B, Rajewsky K. A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody secreting hybrid cell lines. J Immunol 1979; 123: 1548
19. Maniatis T, Fritsch EF, Sambrook J. Molecular Cloning: A laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1982
20. Chomczynski P, Sacchi N. Single step method of RNA isolation by acid guanidium thiocyanate-phenol chloroform extraction. Anal Biochem 1987; 162: 156
21. Kabat EA, Wu TT, Reid-Miller M, Perry HM, Gottesman KS. Sequence of Proteins of Immunological Interest. Washington: US Dept Health and Human Serv NIH, 1987: 4th edn
22. Lewis AP, Crowe JS. Immunoglobulin complementary-determining region grafting by recombinant polymerase chain reaction to generate humanised monoclonal antibodies. Gene 1991; 101: 297
23. Ho SN, Hunt HD, Horton RM, Pullen JK, Pease LR. Site directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 1989; 77: 51
24. Horton RM, Hunt HD, Ho S, Pullen JK, Pease LR. Engineering hybrid genes without the use of restriction enzymes: Gene splicing by overlap extension. Gene 1989; 77: 61
25. Toneguzzo F, Hayday AC, Keating A. Electric field mediated DNA transfer: Transient and stable gene expression in human and mouse lymphoid cells. Mol Cell Biol 1986; 6: 703
26. Laemmli UK. Cleavage of structural protein during assembly of bacteriophage T4. Nature 1970; 227: 680
27. Kumpel BM. A simple non-isotopic method for the quantitation of red cell-bound immunoglobulin. Vox Sang 1990; 59: 34
28. Ducrot T, Beliard R, Glacet A, Klein P, Harbonnier S, Benmostefa N, Bourel D. Use of the DAF assay to assess the functional properties of polyclonal and monoclonal Rh(D) antibodies. Vox Sang 1996; 71: 30
29. Sawada H, Iwasa S, Nishimura O, Kitano K. Efficient production of anti-hepatitis B virus antibodies and their neutralizing activity in chimpanzees. Appl Microbiol Biotechnol 1995; 43: 445
30. Caroll WL, Mendel E, Levy S. Hybridoma fusion cell lines contain an aberrant κ transcript. Mol Immunol 1988; 25: 991
31. Tandai M, Endo T, Sasaki S, Masuho Y, Kochibe N, Kobata A. Structural study of the sugar moieties of monoclonal antibodies secreted by human-mouse hybridoma. Arch Biochem Biophys 1991; 291: 339
32. Poljak RJ, Amzel LM, Avery HP, Chen BL, Phizackerley RP, Saul F. Three-dimensional structure of the Fab′ fragment of a human immunoglobulin at the 2.8A resolution. Proc Natl Acad Sci USA 1973; 70: 3305
33. Greenspan NS, Cooper LJN. Intermolecular cooperativity: A clue to why mice have IgG3? Immunology Today 1992; 13: 164
34. Cooper LJN, Shikhman AR, Glass DD, Kangisser D, Cunningham MW, Greenspan NS. Role of heavy chain constant domains in antibody-antigen interactions. J Immunol 1993; 150: 2231
35. Chapman PB, Gillies SD, Houghton AN, Reilly RM. Mapping effector functions of a monoclonal antibody to GD3 by characterization of a mouse-human chimeric antibody. Cancer Immunol Immunother 1994; 39: 198