Bile acid inhibition of interferon activity in human lymphocytes: No evidence of oxidative stress

European Journal of Clinical Investigation

Volumn 27, Issue 6, 1997, Pages 491-496

  Podevin, P ^a,b   Blanc, M C ^a   Vaubourdolle, M ^a   Veyrunes, C ^a   Bonnefis, M T ^a   Poupon, R ^a  

^a HÔPITAL SAINT ANTOINE   (France)

^b ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

Author keywords

2'.5' oligoadenylate synthetase; Bile acids; Chenodeoxycholic acid; Interferon; Oxidative stress

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE; BILE ACID; CHENODEOXYCHOLIC ACID; GLUTATHIONE; INTERFERON; MALONALDEHYDE;

ANTIOXIDANT ACTIVITY; ARTICLE; CHOLESTASIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HEPATITIS C; HUMAN; HUMAN CELL; IMMUNOTHERAPY; LYMPHOCYTE; OXIDATIVE STRESS; PRIORITY JOURNAL;

EID: 0030856655     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.1997.1360683.x     Document Type: Article

References (41)

1. Davis GL, Balart LA, Schiff ER et al. Treatment of chronic hepatitis C with recombinant interferon alfa: a multicenler randomized, controlled trial. N Engl J Med 1989;321:1501-6.
2. Di Bisceglie AM, Martin P, Kassianides C et al. Recombinant interferon alfa therapy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial. N Engl J Med 1984;321: 1506-10.
3. Marcellin P, Boyer N, Giostra E et al. Recombinant human alpha-interferon in patients with chronic non-A non-B hepatitis: a multicenter randomized controlled trial from France. Hepatology 1991;13:393-7.
4. Tiné F, Magrin S, Craxi A, Pagliaro L. Interferon for non-A, non-B chronic hepatitis. A meta-analysis of randomized clinical trials. J Hepatol 1991;13:192-9.
5. Hino K, Sainokami S, Shimoda K et al. Genotypes and titers of hepatitis C virus for predicting response to interferon in patients with chronic hepatitis C. J Med Virol 1994;42:299-305.
6. Hagiwara H, Hayashi N, Mita E et al. Quantitative analysis of hepatitis C virus RNA in serum during interferon alfa therapy. Gastroenterology 1993;104:877-83.
7. Camps J, Crisostomo S, Garcia-Granero M, Riezu-Boj JI, Civeira MP, Prieto J. Prediction of the response of chronic hepatitis C to interferon alfa: a statistical analysis of pretreatment variables. Gut 1993;34:1714-7.
8. Jouët P, Roudot-Thoraval F, Dhumeaux D, Métreau J-M, NANB C-1 Lgpléeltdhe. Comparative efficacy of interferon alfa in cirrhotic and noncirrhotic patients with non-A, non-B, C hepatitis. Gastroenterology 1994;106:686-90.
9. Serfaty L, Giral P, Loria A, Andréani T, Legendre C, Poupon R. Factors predictive of the response to interferon in patients with chronic hepatitis C. J Hepatol 1994;21:12-17.
10. Podevin P, Calmus Y, Bonnefis M, Veyrunes C, Chéreau C, Poupon R. Effect of cholestasis and bile acids on interferon-induced 2′,5′-adenylate synthetase and natural killer activities. Gastroenterology 1995;108:1192-8.
11. Sobol RW, Fisher WL, Reichenbach NL et al. HIV-1 reverse transcriptase: inhibition by 2′,5′-oligoadenylates. Biochemistry 1993;32:12112-18.
12. Chebath J, Benech P, Revel M, Vigneron M. Constitutive expression of (2′-5′) oligo A synthetase confers resistance to picornavirus infection. Nature 1987;330:587-8.
13. Staal FJT, Roederer M, Israelski DM. Intracellular glutathione levels in T cells substs decrease in HIV infected individuals. AIDS Res Hum Retroviruses 1992;8:305-11.
14. Suarez M, Beloqui O, Ferrer J et al. Glutathione depletion in chronic hepatitis C. Intern Hepatol Commun 1993;1:215-21.
15. Schreck R, Rieber P, Baeuerle PA. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappaB transcription factor and HIV-1. EMBO J 1991;10: 2247-58.
16. Beloqui O, Prieto J, Suàrez M et al. N-acetyl cysteine enhances the response to interferon-a in chronic hepatitis C: a pilot study. J Interferon Res 1993;13:279-82.
17. Singh S, Shackleton G, Ah-Sing E, Chakraborty J, Bailey M. Antioxidant defenses in the bile duct-ligated rat. Gastroenterology 1992;103:1625-9.
18. Sokol RJ, Devereaux M, Khandwala R, O'Brien K. Evidence for involvement of oxygen free radicals in bile acid toxicity to isolated rat hepatocytes. Hepatology 1993;17:869-81.
19. Tucker SB, Pierre RV, Jordon RE. Rapid identification of monocyles in a mixed mononuclear cell preparation. J Immunol Methods 1977;14:267-9.
20. Merlin G, Revel M, Wallach D. The interferon-induced enzyme oligo-isoadenylate synthetase: rapid determination of its in vitro products. Anal Biochem 1981;110:190-6.
21. Gmûnder H, Eck HP, Benninghoff B, Roth S, Drôge W. Macrophages regulate intracellular glutathione levels of lymphocytes. Evidence for an immunoregulatory role of cysteine. Cell Immunol 1990;129:32-46.
22. Liang CM, Lee N, Cattell D, Liang SM. Glutathione regulates interleukin-2 activity on cytotoxic T-cells. J Biol Chem 1989;264: 13519-23.
23. Meister A. Glutathione metabolism and its selective modification. J Biol Chem 1988;263:17205-8.
24. Ting C, Hargrove M, Liang S, Liang C, Sharrow S. Dichotomy of glutathione regulation of the activation of resting and preactivated lymphocytes. Cell Immunol 1992;142:40-53.
25. Hamilos DL, Wedner HJ. Comparison of inhibitory effects of buthionine sulfoximine and 2-cyclohexene-1-one by nuclear size transformation. J Immunol 1985;135:2740-7.
26. Drôge W, Pottmeyer-Gerber C, Schmidt H, Nicks S. Glutathione augments the activation of cytotoxic T lymphocytes in vivo. Immunobiology 1986;172:151-6.
27. Pierri C, Moroni F, Recchioni R. Glutathione influences the proliferation as well as the extent of mitochondrial activation in rat splenocytes. Cell Immunol 1992;145:210-17.
28. Staal FJT, Ela SW, Roederer M, Anderson MT, Herzenberg LA, Herzenberg LA. Glutathione deficiency and human immunodeficiency virus infection. Lancet 1992;309:909-12.
29. Garaci E, Palamara A, Di Francesco P, Favalli C, Ciriolo M, Rotilio G. Glutathione inhibits replication and expression of viral proteins in cultured cells infected with Sendai virus. Biochem Biophys Res Commun 1992;188:1090-6.
30. Raju PA, Herzenberg LA, Herzenberg LA, Roederer M. Glutathione precursor and antioxidant activities of N-acetylcysteine and oxothiazolidine carboxylate compared in in vitro studies of HIV replication. AIDS Res Hum Retroviruses 1994;10:961-7.
31. Calmus Y, Guéchot J, Podevin P, Bonnetis MT, Giboudeau J, Poupon R. Differential effects of chenodeoxycholic and ursodeoxycholic acids on interleukin 1, interleukin 6 and tumor necrosis factor - production by monocytes. Hepatology 1992;16: 719-23.
32. Calmus Y, Weill B, Ozier Y, Chéreau C, Houssin D, Poupon R. Immunosuppressive properties of chenodeoxycholic and ursodeoxycholic acids in the mouse. Gastroenterology 1992;103: 617-21.
33. Calmus Y, Podevin P, Robert A, Poupon R. Differential effects of chenodeoxycholic and ursodeoxycholic acids on expression of procoagulant activity by human monocytes. J Hepatol 1994;20: 466-72.
34. Greve JW, Gouma DJ, Buurman W. Bile acids inhibit endotoxin-induced release of tumor necrosis factor by immocytes: an in vitro study. Hepatology 1989;10:454-8.
35. Lacaille F, Paradis K. The immunosuppressive effect of ursodeoxycholic acid: a comparative in vitro study on human peripheral blood mononuclear cells. Hepatology 1993;18:165-72.
36. Yoshikawa M, Tsujii T, Matsumura K et al. Immunomodulatory effects of ursodeoxycholic acid on immune responses. Hepatology 1992;16:358-64.
37. Zimber A, Chedeville A, Gespach C, Abita JP. Inhibition of proliferation and induction of monocytic differentiation in HL60 human promyelocytic leukemia cells treated with bile acids in vitro. Int J Cancer 1994;59:71-7.
38. Hirano F, Tanaka H, Makino I. Chenodeoxycholic acid-dependent induction of major histocompatibility complex class I mRNA expression in a human hepatoma cell line. Biochem Biophys Res Commun 1993;195:1408-14.
39. Hillaire S, Boucher E, Calmus Y et al. Effects of bile acids and cholestasis on major histocompatibility complex class I in human and rat hepatocytes. Gastroenterology 1994;107:781-8.
40. Podevin P, Calmus Y, Robert A, Poupon R, Cherqui G. Inhibition of procoagulant activity of human monocytes by chenodeoxycholic acid: involvement of protein kinase C. Hepatology 1994; 19:1164-70.
41. Krahenbuhl S, Fisher S, Talos C, Reichen J. Ursodeoxycholate protects oxidative mitochondrial metabolism from bile acid toxicity: dose-response study in isolated rat liver mitochondria. Hepatology 1994;20:1595-601.