Twenty-four-hour blood pressure monitoring during treatment with extended-release felodipine versus slow-release nifedipine in elderly patients with mild to moderate hypertension: A randomized, double-blind, cross-over study

European Journal of Clinical Pharmacology

Volumn 53, Issue 2, 1997, Pages 95-100

  Bonaduce, D ^a   Canonico, V ^b   Petretta, M ^a   Forgione, L ^b   Ianniciello, A ^a   Cavallaro, V ^a   Bertocchi, F ^b   Rengo, F ^b  

^a Institute of Internal Medicine   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Felodipine ER; Hypertension

Indexed keywords

FELODIPINE; NIFEDIPINE; PLACEBO;

AGED; AMBULATORY MONITORING; ARTICLE; BLOOD PRESSURE MONITORING; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CROSSOVER PROCEDURE; DIASTOLIC BLOOD PRESSURE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; ESSENTIAL HYPERTENSION; FEMALE; HUMAN; MALE; OUTPATIENT DEPARTMENT; PATIENT COMPLIANCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STATISTICAL ANALYSIS; SUSTAINED RELEASE PREPARATION; SYSTOLIC BLOOD PRESSURE;

AGED; AGED, 80 AND OVER; BLOOD PRESSURE; BLOOD PRESSURE MONITORING, AMBULATORY; CALCIUM CHANNEL BLOCKERS; CROSS-OVER STUDIES; DELAYED-ACTION PREPARATIONS; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FELODIPINE; FEMALE; HUMANS; HYPERTENSION; MALE; NIFEDIPINE;

EID: 0030856103     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050344     Document Type: Article

References (34)

1. Amery A, Birkenhäger W, Brixko P, Bulpitt C, Clement D, Deruyttere M, De Schaepdryver A, Dollery C, Fagard R, Forette F, Forte J, Handy R, Henry JF, Joossens JV, Leonetti G, Lund-Johansen P, O' Malley K, Petrie J, Strasser T, Tuomilehto J, Williams B (1985) Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly Trial. Lancet i: 1349-1354
2. Dahlöf B, Lindholm LH, Hansson L, Scherstén B, Ekbom T, Wester P-O (1991) Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension). Lancet 338: 1281-1285
3. MRC Working Party (1992) Medical Research Council Trial of treatment of hypertension in older adults: principal results. BMJ 304: 405-412
4. SHEP Cooperative Research Group (1991) Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA 265: 3255-3264
5. Coope J, Warrender T (1986) Randomized trial of treatment of hypertension in the elderly patients in primary health care. BMJ 293: 1145-1151
6. Gong L, Zhang W, Zhu Y, Zhu J, 11 collaborating centres in the Shanghai area, Kong D, Pagé V, Ghadirian P, Le Lorier J, Hamet P (1996) Shanghai Trial of Nifedipine in the Elderly (STONE). J Hypertens 14: 1237-1245
7. Ronn O, Bengtsson B, Edgar B, Raner S (1985) Acute haemodynamic effects of felodipine and verapamil in man. singly and with metoprolol. Drugs 29[suppl 2]: 16-25
8. Blychert E, Edgar B, Elmfeldt D, Hedner T (1992) Plasma concentration-effect relationships for felodipine - a meta analysis. Clin Pharmacol Ther 52: 80-89
9. Mace PJTE, Stallard TJ, Littler WA (1985) Felodipine in hypertension. Eur J Clin Pharmacol 29: 383-389
10. McGrath BP, Langton D, Matthews PC, Syme S, Treloar K, McNeil JJ (1989) Comparison of felodipine extended release and conventional tablets in essential hypertension using ambulatory blood pressure monitoring. J Hypertens 7: 645-651
11. Hosie J, Mulder AW, Westberg B for the Binational MC Study Group (United Kingdom and Netherlands) (1991) Felodipine once daily in elderly hypertensives. J Hum Hypertens 5: 49-53
12. Morgan TO, Anderson A, Jones E (1992) Comparison and interaction of low dose felodipine and enalapril in the treatment of essential hypertension in elderly subjects. Am J Hypertens 5: 238-243
13. Hornung RS, Gould BA, Jones RI, Sonecha T, Raftery EB (1983) Nifedipine tablets for hypertension: a study using continuous ambulatory intra-arterial recording. Am J Cardiol 51: 1323-1327
14. Bonaduce D, Canonico V, Mazza F, Nicocino A, Ferrara N, Chariello M, Condorelli M (1985) Evaluation of the efficacy of slow-release nifedipine in systemic hypertension by ambulatory intraarterial blood pressure monitoring. J Cardiovasc Pharmacol 7: 145-151
15. Nifedipine-Atenolol Study Review Committee (1988) Nifedipine and atenolol singly and combined for treatment of essential hypertension: comparative multicentre study in general practice in the United Kingdom BMJ. 296: 468-472
16. Perloff D, Grim C, Flack J, Frohlich E, Hill M, Mc Donald M, Moregenstern BZ, Writing Group (1993) Human blood pres- sure determination by sphygmomanometry. Circulation 88: 2460-2467
17. Casadei R, Parati G, Pomidossi G (1988) 24-hour blood pressure monitoring: evaluation of Spacelabs 5300 monitor by comparison with intra-arterial blood pressure recording in ambulant subjects. J Hypertension 6: 797-803
18. Carroll J, Shamiss A, Zevin D, Levi J, Rosenthal T (1995) Twenty-four-hour blood pressure monitoring during treatment with extended-release felodipine versus slow-release nifedipine: cross-over study. J Cardiovasc Pharmacol 26: 974-977
19. Myers MG, Leenen FHH, Tanner J (1995) Differential effects of felodipine and nifedipine on 24-h blood pressure and left ventricular mass. Am J Hypertens 8: 712-718
20. Weber MA, Goldberg AI, Faison EP, Lipschutz K, Shapiro DA, Nelson EB, Irvin JD, for the Felodipine ER Dose-Response Study Group (1994) Extended-release felodipine in patients with mild to moderate hypertension. Clin Pharmacol Ther 55: 346-352
21. Ibsen H, Westberg B for the Scandinavian Multicenter Group (1990) The efficacy and tolerability of long-term felodipine treatment in hypertension. Cardiovasc Drug Ther 4: 641-648
22. Hosie J, Langan JJ, Scott M, Vernon JP, Dawson A (1992) Effectiveness and tolerability of felodipine once daily and nifedipine twice daily as monotherapies for mild hypertension. J Drug Dev 5: 129-136
23. Fariello R, Boni E, Corda L, Cantalamessa A, Zaninelli A, Pollavin G, Alicandri C, Muiesan G (1991) Extended-release felodipine in essential hypertension: variations in blood pressure during whole-day continuous ambulatory recording. Am J Hypertens 4: 27-33
24. Wing LM, Russell AE, Tonkin AL, Bune AJ, West MJ, Chalmers JP (1994) Felodipine, metoprolol and their combination compared with placebo in isolated systolic hypertension in the elderly. Blood Pressure 3: 82-89
25. Wing LM, Russell AE, Tonkin AL, Watts RW, Bune AJ, West MJ, Chalmers JP (1994) Mono- and combination therapy with felodipine or enalapril in elderly patients with systolic hypertension. Blood Pressure 3: 90-96
26. Landahl S, Edgar B, Gabrielsson N (1988) Pharmacokinetics and blood pressure effects of felodipine in elderly hypertensives patients. A comparison with young healthy subjects. Clin Pharmacokinet 14: 374-383
27. Chung M, Reitberg DP, Gaffney M, Singleton W (1987) Clinical pharmacokinetics of nifedipine gastrointestinal therapeutic system: a controlled-release formulation of nifedipine. Am J Med 87[Suppl 6B]: 10-14
28. Omboni S, Parati G, Zanchetti A, Mancia G (1995) Calculation of trough:peak ratio of antihypertensive treatment from ambulatory blood pressure: methodological aspects. J Hypertens 13: 1105-1112
29. Elliott HL, Meredith PA (1994) Methodological considerations in calculation of the trough:peak ratio. J Hypertens 12[Suppl 8]: S3-S7
30. Rose M, McMahon FG (1990) Some problems with antihypertensive drug studies in the context of the new guidelines. Am J Hypertens 3: 151-155
31. Myers MG (1994) Dihydropyridine calcium antagonists and the trough:peak ratio: focus on adverse effects. J Hypertens 12[Suppl 8]: S73-S77
32. Parati G, Pomidossi G, Albini K, Malaspina D, Mancia G (1987) Relationship of 24-hour blood pressure mean and variability to severity of target-organ damage in hypertension. J Hypertens 5: 93-98
33. Frattola A, Parati G, Cuspidi C, Albini K, Mancia G (1993) Prognostic value of 24-hour blood pressure variability. J Hypertens 11: 1133-1137
34. Campbell LM, Cowen KJ, Cranfield FR, Goves JR, Jones DF, Lees CTW, Richardson PDI, Teal JA, Timerick SJB (1990) Felodipine-ER once daily as monotherapy in hypertension. J Cardiovasc Pharmacol 15: 569-573