Modeling of internal pH, ion concentration, and bioenergetic changes during myocardial ischemia

Advances in Experimental Medicine and Biology

Volumn 430, Issue , 1997, Pages 281-290

  Ch'en, Frederick ^a   Clarke, Kieran ^b   Vaughan Jones, Richard ^c   Noble, Denis ^b  

^a BALLIOL COLLEGE   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOENERGY; CELL PH; GUINEA PIG; HEART HEMODYNAMICS; HEART MUSCLE ISCHEMIA; NONHUMAN; PATHOPHYSIOLOGY; PH MEASUREMENT; PRIORITY JOURNAL; RABBIT;

CAVIA PORCELLUS; ORYCTOLAGUS CUNICULUS; SUS SCROFA;

EID: 0030856021     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-5959-7_24     Document Type: Article

References (10)

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2. Noble D. Ionic mechanisms determining the timing of ventricular repolarisation: significance for cardiac arrhythmias. Ann NY Acad Sci 1991;644:1-22.
3. Winslow R, Varghese A, Noble D, Adlakha C, Hoythya A. Generation and propagation of triggered activity induced by spatially localised Na-K pump inhibition in atrial network models. Proc Roy Soc 1993;B254:55-61.
4. Allen DG, Ordhard CH. Myocardial contractile function during ischemia and hypoxia. Circ Res 1987;60:153-168.
5. Lagadic-Gossmann D, Buckler KJ, Vaughan-Jones RD. Role of bicarbonate in pH recovery from intracellular acidosis in the guinea-pig ventricular myocyte. J Physiol 1992;458:361-348
6. Bountra C, Vaughan-Jones RD. Effects of intracellular and extracellular pH on contraction in isolated mammalian cardiac muscle. J Physiol 1989;418:163-187.
7. + exchange inhibitor and its effects in cardiac ischemia. Br J Pharmacol 1993;109:562-568.
8. 31P NMR spectroscopy and phosphonate markers. Magn Resn Med 1994;32: 181-188.
9. Sun B, Leem CH, Vaughan-Jones RD. Novel chloride-dependent acid loader in the guinea-pig ventricular myocyte: part of a dual acid-loading mechanism. J Physiol 1996;495:65-82.
10. Clarke K, O'Connor AJ, Willis RJ. Temporal relation between energy metabolism and myocardial function during ischemia and reperfusion. Am J Physiol 1987;253:H412-421.