HNPCC-Lynch syndrome and idiopathic inflammatory bowel disease. A hypothesis on sharing of genes

Anticancer Research

Volumn 17, Issue 4 A, 1997, Pages 2647-2649

  Caruso, Maria Lucia ^a   Cristofaro, G ^b   Lynch, H T ^c  

^a NATIONAL INSTITUTE FOR DIGESTIVE DISEASES   (Italy)

^b Hered Gastrointest Cancer Prev C   (Italy)

^c CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Genetic hypothesis; IBD; Lynch syndrome

Indexed keywords

ADULT; ARTICLE; CANCER RISK; CASE REPORT; COLON MUCOSA; COLORECTAL CANCER; DISEASE ASSOCIATION; DISEASE CARRIER; ENTERITIS; FAMILIAL CANCER; GENETIC ANALYSIS; GENETIC PREDISPOSITION; HEREDITY; HUMAN; MALE; PATHOGENESIS; PRIORITY JOURNAL; SYMPTOM;

COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; HUMANS; INFLAMMATORY BOWEL DISEASES; MALE; PEDIGREE;

EID: 0030855682     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Lynch HT, Smyrk T, Lanspa S, Lynch J: Colonoscopy in relation to the evolving genetics of familial colorectal cancer. Endoscopy 27: 43- 49, 1995.
2. Kern SE, Reason M, Seymour AB, Caldas C, Powell SM, Kornacki S, Kinzler KW: Molecular genetic profiles of colitis-associated neoplasm. Gastroenterology 107: 420-428, 1994.
3. Suzuki H, Harpaz N, Tarmin L: Microsatellite instability in ulcerative colitis-associated colorectal dysplasias and cancers. Cancer Res 54: 4841-4844, 1994.
4. Cristofaro G, Lynch HT, Caruso ML, Attolini A, Di Matteo G, Giorgio P, Senatore S, Argentieri A, Sbano E, Guanti G, Fusaro R, Giorgio I: New phenotypic aspects in a family with Lynch Syndrome II. Cancer 60: 51-58, 1987.
5. Rosin MP, Anwar WA, Ward AJ: Inflammation, chromosomal instability, and cancer: the schistosomiasis model. Cancer Res (suppl) 54-1929s-1933s, 1994.
6. Mayberry JF, Ballantyne KC, Hardcastle JD, Mangham C, Pye G: Epidemiological study, of asymptomatic inflammatory bowel disease: the identification of cases during a screening programme for colorectal cancer. Gut 30: 481-483, 1989.
7. Lewin KJ, Riddel RH, Weinstein WM.: Gastrointestinal pathology and its clinical implications. Vol.II, New York, Igaku-Shoin, 1989, p 930.
8. Lynch HT, Smyrk TC, Watson P, Lanspa SJ, Lynch JF, Lynch PM, Cavalieri RJ, Boland CR: Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review. Gastroenterology 104: 1535-1549, 1993.
9. Yang H, Rotter JI, Tojoda H, Landers C, Twan D, McElree CK, Targan SR: Ulcerative colitis: a genetically heterogeneous disorder defined by genetic (HLA Classe II) and subclinical (Antineutrophil Cytoplasmic Antibodies) markers. J Clin Invest 92: 1080-1084, 1993.
10. Dignass A, Goebell H: Genetics of inflammatory bowel disease. Current Opinion in Gastroenterology 11: 292-297, 1995.
11. Satsangi J, Jewell DP, Rosenberg WMC, Bell JI: Genetics of inflammatory bowel disease. Gut 35: 696-700, 1994.
12. Crotty B: Ulcerative colitis and xenobiotic metabolism. Lancet 343: 35-38, 1994.
13. Noffsinger AE, Straughen J, Groden J, Fenoglio-Preiser C: Microsatellite instability in neoplastic and non-neoplastic lesions of ulcerative colitis. Mod Pathol 8: 66A,1995.
14. Brentnall TA, Chen R, Lee JG, Kimmey MB, Bronner MP, Haggitt RC, Kowdley KV, Hecker LM, Byrd DR: Microsatellite instability and K-ras mutations associated with pancreatic adenocarcinoma and pancreatitis. Cancer Res 55: 4264-4267, 1995.
15. Brentnall TA, Crispin DA, Bronner MP, Cherian SP, Hueffed M, Rabinovitc PS, Rubin CE, Haggitt RC, Boland CR: Microsatellite instability in nonneoplastic mucosa from patients with chronic ulcerative colitis. Cancer Res 56: 1237-1240, 1996.
16. Brentnall TA, Rubin CE, Crispin DA, Stevens A, Batchelor RH, Haggitt RC, Bronner MP, Evans JP, McCahill LE, Bilir N, Boland CR, Rabinovitch PS: A germline substitution in the human MSH2 gene is associated with high-grade dysplasia and cancer in ulcerative colitis. Gastroenterology 109: 151-155, 1995.
17. Noffsinger AE, Heinen C, Groden J, Fenoglio-Preiser CM: The relationship between germline hMSH2 gene alterations, dysplasia and microsatellite instability in patients with ulcerative colitis. Mod Pathol 9: 63A, 1996.
18. Prolla TA, Pang Q, Alani E, Kolodner RD, Liskay RM. MLHI, PMSI, and MSH2 interactions during the initiation of DNA mismatch repair in yeast: Science 265: 1091-1093, 1994.
19. Aaltonen LA, Peltomaki P, Leach FS: Clues to the pathogenesis of familial colorectal cancer. Science 260: 812-816, 1993.
20. Liu B, Parsons RE, Hamilton SR, Petersen GM, Lynch HT, Watson P, Markowitz S, Willson JKV, Green J, de la Chapelle A, Kinzler KW, Vogelstein B: h ∼ SH2 mutations in hereditary nonpolyposis colorectal cancer kindreds. Cancer Res 54: 4590-4594, 1994.