Dimerization of Cdc25p, the guanine-nucleotide exchange factor for ras from Saccharomyces cerevisiae, and its interaction with Sdc25p

European Journal of Biochemistry

Volumn 247, Issue 2, 1997, Pages 703-708

  Camus, Christelle ^a   Geymonat, Marco ^a   Garreau, Hervé ^a   Baudet Nessler, Sylvie ^b   Jacquet, Michel ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b LABORATOIRE D ENZYMOLOGIE ET BIOCHIMIE STRUCTURALES   (France)

Author keywords

Cellular signalization; Guanine exchange factor; Ras protein; Two hybrid system

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR;

ARTICLE; DIMERIZATION; ESCHERICHIA COLI; GEL FILTRATION; GENE EXPRESSION; IMMUNOPRECIPITATION; OLIGOMERIZATION; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN STRUCTURE; SACCHAROMYCES CEREVISIAE;

ESCHERICHIA COLI; SACCHAROMYCES CEREVISIAE;

EID: 0030855008     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1997.00703.x     Document Type: Article

References (30)

1. Camonis, J. H., Kalékine, M., Gondré, B., Garreau, H., Boy-Marcotte, E. & Jacquet, M. (1986) Characterization, cloning and sequence analysis of the CDC25 gene which controls the cyclic AMP level of Saccharomyces cerevisiae, EMBO J. 5, 375-380.
2. Martegani, E., Baroni, M. D., Frascotti, G. & Alberghina, L. (1986) Molecular cloning and transcriptional analysis of the start gene CDC25 of Saccharomyces cerevisiae: EMBO J. 5, 2363-2369.
3. Broek, D., Toda, T., Michaeli, T., Levin, L., Birchmeier, C., Zoller, M., Powers, S. & Wigler, M. (1987) The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway. Cell 48, 789-799.
4. Boy-Marcotte, E., Ikonomi, P. & Jacquet, M. (1996) SDC25, a dispensable Ras guanine nucleotide exchange factor of Saccharomyces cerevisiae differs from CDC25 by its regulation, Mol. Biol. Cell 7, 529-539.
5. Damak, F., Boy-Marcotte, E., Le-Roscouet, D., Guilbaud, R. & Jacquet, M. (1991) SDC25, a CDC25 like gene, which contains a RAS-activating domain is a dispensable gene of Saccharomyces cerevisiae, Mol. Cell. Biol. 11, 202-212.
6. Boy-Marcotte, E., Damak, F., Camonis, J., Garreau, H. & Jacquet, M. (1989) The C-terminal part of a gene partially homologous to CDC25 gene suppresses the cdc25-5 mutation in Saccharomyces cerevisiae, Gene 77, 21-30.
7. Aronheim, A., Engelberg, D., Li, N., Al-alawi, N., Schlessinger, J. & Karin, M. (1994) Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway. Cell 78, 949-961.
8. Chen, L., Zhang, L., Greer, P., Tung, P. S. & Moran, M. F. (1993) A murine CDC25/ras-GRF-related protein implicated in Ras regulation. Dev. Genet. 14, 339-346.
9. Schweighoffer, F., Faure, M., Fath, I., Chevallier-Multon, M. C., Apiou, F., Dutrillaux, B., Sturani, E., Jacquet, M. & Tocque, B. (1993) Identification of a human guanine nucleotide-releasing factor (H-GRF55) specific for Ras proteins, Oncogene 8, 1477-1485.
10. Martegani, E., Vanoni, M., Zippel, R., Coccetti, P., Brambilla, R., Ferrari, C., Sturani, E. & Alberghina, L. (1992) Cloning by functional complementation of a mouse cDNA encoding a homologue of CDC25, a Saccharomyces cerevisiae RAS activator, Embo J. 11, 2151-2157.
11. Ferrari, C., Zippel, R., Martegani, E., Gnesutta, N., Carrera, V. & Sturani, E. (1994) Expression of two different products of CDC25Mm, a mammalian Ras activator, during development of mouse brain. Exp. Cell Res. 210, 353-357.
12. Kaplon, T. & Jacquet, M. (1995) The cellular content of Cdc25p, the Ras exchange factor in Saccharomyces cerevisiae. is regulated by destabilization through a cyclin destruction box, J. Biol. Chem. 270, 20 742-20 747.
13. Gross, E., Goldberg, D. & Levitzki, A. (1992) Phosphorylation of the S, cerevisiae Cdc25 in response to glucose results in its dissociation from Ras, Nature 360, 762-765.
14. Garreau, H., Geymonat, M., Renault, G. & Jacquet, M. (1996) Membrane-anchoring domains of Cdc25p, a Saccharomyces cerevisiae ras exchange factor, Biol. Cell 86, 93-102.
15. Camus, C., Hermann-Le Denmat, S. & Jacquet, M. (1995) Identification of guanine exchange factor key residues involved in exchange activity and Ras interaction, Oncogene 11, 951-959.
16. Garreau, H., Camonis, J. H., Guitton, C. & Jacquet, M. (1990) The Saccharomyces cerevisiae CDC25 gene product is a 180 kD polypeptide and is associated to a membrane fraction, FEBS Lett. 269, 53-59.
17. Gross, E., Marbach, I., Engelberg, D., Segal, M., Simchen, G. & Levitzki, A. (1992) Anti-Cdc2S antibodies inhibit guanyl nucleotide-dependent adenylyl cyclase of Saccharomyces cerevisiae and cross-react with a 150-kilodalton mammalian protein, Mol. Cell. Biol. 12, 2653-2661.
18. Fields, S. & Song, O. (1989) A novel genetic system to detect protein-protein interaction, Nature 340, 245-246.
19. Kawashima, T., Berthet, C. C., Wulff, M., Cusack, S. & Leberman, R. (1996) The structure of the Escherichia coli EF-Tu. EF-Ts complex at 2.5 Å resolution. Nature 379, 511-518
20. Marshall, C. J. (1996) Raf gets it together, Nature 383, 127-128.
21. Farrar, M. A., Alberola-Ila, J. & Perlmutter, R. M. (1996) Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization, Nature 383, 178-181.
22. Luo, Z., Tzivion, G., Belshaw, P. J., Vavvas, D., Marshall, M. & Avruch, J. (1996) Oligomerization activates c-Raf-1 through a Ras-dependent mechanism, Nature 383, 181-185.
23. Zelicof, A., Protopopov, V., David, D., Lin, X. Y., Lustgarten, V. & Gerst, J. E. (1996) Two separate functions are encoded by the carboxyl-terminal domains of the yeast cyclase-associated protein and its mammalian homologs. Dimerization and actin binding, J. Biol. Chem. 271, 18243-18252.
24. Bartel, P., Chien, C., Sternglanz, R. & Fields, S. (1993) Elimination of false positives that arise in using the two-hybrid system, Bio-Techniques 14, 920-924.
25. Heinemeyer, W., Kleinschmidt, J., Saidowsky, J., Escher, C. & Wolf, D. (1991) Proteinase yscE, the yeast proteasome/multicatalytic-multifunctional proteinase: mutants unravel its function in stress induced proteolysis and uncover its necessity for cell survival. EMBO J. 10, 555-562.
26. Bartel, P., Chien, C., Sternglanz, R. & Fields, S. (1993) Using the two-hybrid system to detect protein-protein interactions, in Cellular interactions in development: a practical approach (Hartley, D. A., ed.) pp. 153-179, Oxford University Press, Oxford.
27. Cullin, C. & Minvielle-Sebastia, L. (1994) Multipurpose vectors designed for the fast generation of N- or C-terminal epitope-tagged proteins. Yeast 10, 105-112.
28. Poullet, P., Créchet, J., Bernardi, A. & Parmeggiani, A. (1995) Properties of the catalytic domain of Sdc25p, a yeast GDP/GTP exchange factor of Ras proteins, Eur. J. Biochem. 227, 537-544.
29. Camus, C., Boy-Marcotte, E. & Jacquet, M (1994) The ras guanine exchange factor domains of CDC25 and SDC25 differ from that of BUD5, thus allowing to derive subfamilies among CDC25-related GEFs, Mol. Gen. Genet. 245, 167-176.
30. Zhang, G., Liu, Y., Ruoho, A. E. & Hurley, J. H. (1997) Structure of the adenylyl cyclase catalytic core. Nature 386, 247-253.