A process for the recovery of poly(hydroxyalkanoates) from pseudomonads part 2: Process development and economic evaluation

Bioprocess Engineering

Volumn 17, Issue 1, 1997, Pages 15-21

  De Koning, G J M ^a   Kellerhals, M ^a   Van Meurs, C ^a   Witholt, B ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHEMICAL ANALYSIS; COST; ECONOMIC ASPECT; FERMENTATION; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONADACEAE;

EID: 0030854003     PISSN: 0178515X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004490050346     Document Type: Article

References (19)

1. Anderson, A.J.; Dawes, E.A.: Occurrence, metabolism, metabolic role, and industrial uses of bacterial polyhydroxyalkanoates. Microbiol. Rev. 54 (1990), 450-472
2. Holmes, P.A.: Applications of PHB - a microbially produced biodegradable thermoplastic. Phys. Technol. 16 (1985), 32-36
3. De Smet, M.J.; Eggink, G.; Witholt, B.; Kingma, J.; Wynberg, H.: Characterization of intracellular inclusions formed by Pseudomonas oleovorans during growth on octane. J. Bacteriol. 154 (1983), 870-878
4. De Koning, G.J.M.; Witholt, B.: A process for the recovery of poly (hydroxyalkanoates) from Pseudomonads 1. Solubilization. Bioeng. (1996), to be published
5. Holmes, P.A.; Lim, G.B.: Separation process. US Patent 4 910 145 (1990).
6. De Koning, G.J.M.; Lemstra, P.J.: The amorphous state of bacterial poly[(R)-3-hydroxyalkanoate] in vivo. Polymer 33 (1992), 3292-3294
7. Gagnon, K.D.; Lenz, R.W.; Farris, R.J.; Fuller, R.C.: Crystallization behavior and its influence on the mechanical properties of a thermoplastic elastomer produced by Pseudomonas oleovorans. Macromol. 25 (1992), 3723-3728
8. Marchessault, R.H.; Monasterios, C.J.; Morin, F.G.; Sundararajan, P.R.: Chiral poly(beta-hydroxyalkanoates): an adaptable helix influenced by the alkane side-chain. Int. J. Biol. Macromol., 12 (1990), 158-165
9. Marchessault, R.H.; Morin, F.G.; Wong, S.; Saracovan, I.: Artificial granule suspensions of long side chain poly(3-hydroxyalkanoate). Can. J. Microbiol. 41 (1995), 138-142
10. Marchessault, R.H.; Monasterios, C.J.; Lepoutre, P.: in Novel Biodegradable Microbial Polymers (ed. DAWES, E.A.) 97-112 (Kluwer Academic Publishers, 1990).
11. De Koning, G.J.M.; Witholt, B.: Poly(hydroxyalkanoates) from Fluorescent Pseudomonads in retrospect and prospect. J. Env. Biodegr. Pol. 4 (1996), to be published
12. Preusting, H.; Houten, R. van, Hoefs, A.; Kool van Langenberghe, E.; Favre-Bulle, O.; Witholt, B.: High cell density cultivation of Pseudomonas oleovorans: growth and production of poly(3-hydroxyalkanoates) in two-liquid phase batch and fed-batch systems. Biotechnol. Bioeng. 41 (1993), 550-556
13. Lageveen, R.G., Huisman, G.W., Preusting, H., Ketelaar, P., Eggink, G., Witholt, B.: Formation of polyesters by Pseudomonas oleovorans: effect of substrates on formation and composition of poly-(R)-3-hydroxyalkanoates and poly-(R)-3-hydroxyalkenoates. Appl. Environ. Microbiol. 54 (1988), 2924-2932
14. Huijberts, G.N.M.; Vanderwal, H.; Wilkinson, C.; Eggink, G.: Gas-Chromatographic analysis of Poly(3-Hydroxyalkanoates) in bacteria. Biotech. Tech. 8 (1994), 187-192
15. Hori, K.; Soga, K.; Doi, Y.: Effects of culture conditons on molecular weights of poly(3-hydroxyalkanoates) produced by Pseudomonas putida from octanoate. Biotech. Lett. 16 (1994), 709-714
16. Michaels, S.L.: Crossflow microfilters: the ins and outs. Chem. Eng. January (1989), 84-91
17. Miller, C.A.: Cost estimation. Chem. Eng. Magazine 72 (1965), 226-237
18. Holland, F.A.; Watson, F.A.; Wilkinson, J.K.: Chem. Eng. (1973), 118-121
19. Hanggi, U.J.: Requirements on bacterial polyesters as future substitute for conventional plastics for consumer goods. FEMS Microbiol. Rev. 16 (1995), 213-220