Structure-activity studies of bicyclic and tricyclic analogues of methyllycaconitine

Biochemical Society Transactions

Volumn 25, Issue 3, 1997, Pages

  Davies, Andrew R L ^a   Hardick, David J ^a   Blagbrough, Ian S ^a   Potter, Barry V L ^b   Wolstenholme, Adrian J ^b   Wonnacott, Susan ^a  

^a UNIVERSITY OF BATH   (United Kingdom)

^b University of Bath   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLLYCACONITINE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; TERPENOID; UNCLASSIFIED DRUG;

ANIMAL TISSUE; BINDING KINETICS; BRAIN MEMBRANE; CHEMICAL STRUCTURE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ACONITINE; ANIMALS; BINDING, COMPETITIVE; BRAIN; CELL MEMBRANE; KINETICS; MOLECULAR STRUCTURE; NEURONS; RATS; RECEPTORS, NICOTINIC; STRUCTURE-ACTIVITY RELATIONSHIP; TOXINS, BIOLOGICAL;

ANIMALIA;

EID: 0030853550     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/bst025545s     Document Type: Article

References (4)

1. Wonnacott, S., Albuquerque, E.X. and Bertrand D. (1993) Methods in Neurosci. 12, 263-275.
2. Hardick, D.J., Cooper, G., Scott-Ward, T., Blagbrough, I.S., Potter, B.V.L. and Wonnacott, S. (1995) FEBS Lett. 365, 79-82.
3. Hardick, D.J., Blagbrough, I.S., Cooper, G., Potter, B.V.L., Critchley, T. and Wonnacott, S. (1996) J. Med. Chem. 39, 4860-4866.
4. MacAllan, D.R.E., Lunt, G.G., Wonnacott, S., Swanson, K.L., Rapoport, H. and Albuquerque, E.X. (1988) FEBS Lett. 226, 357-363.