Mismatch repair in Schizosaccharomyces pombe requires the mutL homologous gene pms1: Molecular cloning and functional analysis

Genetics

Volumn 146, Issue 4, 1997, Pages 1275-1286

  Schär, Primo ^b,c   Baur, Michel ^a   Schneider, Claudine ^a   Kohli, Jürg ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA POLYMERASE;

AMINO ACID SEQUENCE; ARTICLE; BASE MISPAIRING; CELL VIABILITY; DNA REPAIR; FUNGUS SPORE; GENE DISRUPTION; GENE FUNCTION; GENE MUTATION; GENE STRUCTURE; GENETIC RECOMBINATION; MEIOSIS; NONHUMAN; PRIORITY JOURNAL; SCHIZOSACCHAROMYCES POMBE; SEQUENCE HOMOLOGY;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BASE SEQUENCE; CARRIER PROTEINS; CHROMOSOME MAPPING; CLONING, MOLECULAR; DNA PRIMERS; DNA REPAIR; DNA, FUNGAL; ESCHERICHIA COLI PROTEINS; FUNGAL PROTEINS; GENES, FUNGAL; MEIOSIS; MITOSIS; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; POLYMERASE CHAIN REACTION; SCHIZOSACCHAROMYCES; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; SPORES, FUNGAL;

BACTERIA (MICROORGANISMS); EUKARYOTA; FUNGI; SCHIZOSACCHAROMYCES POMBE;

EID: 0030852869     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (68)

1. ACHARYA, S., T. WILSON, S. GRADIA, M. F. RANK, S. GUERRETTE et al., 1996 hMSH2 forms specific mispair binding complexes with hMSH3 and hMSH6. Proc. Natl. Acad. Sci. USA 93: 13629-13634.
2. ALANI, E., R. A. G. REENAN and R. D. KOLODNER, 1994 Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae. Genetics 137: 19-39.
3. ALANI, E., N-W. CHI and R. KOLODNER, 1995 The Saccharomyces cerevisiae Msh2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertions. Genes Dev. 9: 234-247.
4. AMSTUTZ, H., P. MUNZ, W. D. HEYER, U. LEUPOLD and J. KOHLI, 1985 Concerted evolution of tRNA genes: Intergenic conversion among three unlinked serine tRNA genes in S. pombe. Cell 40: 879-886.
5. Au, K. G., K. WELSH and P. MODRICH, 1992 Initiation of methyldirected mismatch repair. J. Biol. Chem. 267: 12142-12148.
6. BAKER, S. M., C. E. BRONNER, L. ZHANG, A. W. PLUG, M. ROBATZEK et al., 1995 Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis. Cell 82: 309-319.
7. BAKER, S. M., A. W. PLUG, T. A. PROLLA, C. E. BRONNER, A. C. HARRIS et al., 1996 Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over. Nature Genet. 13: 336-342.
8. BARBET, N., W. J. MURIEL and A. M. CARR, 1992 Versatile shuttle vectors and genomic libraries for use with Schizosaccharomyces pombe. Gene 114: 59-66.
9. BRONNER, C. E., S. M. BAKER, P. T. MORRISON, G. WARREN, L. G. SMITH et al., 1994 Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 368: 258-261.
10. COOPER, D. L., R. S. LAHUE and P. MODRIGH, 1993 Methyl-directed mismatch repair is bidirectional. J. Biol. Chem. 268: 11823-11829.
11. DE MASSY, B., V. ROCCO and A. NICOLAS, 1995 The nucleotide mapping of DNA double-strand breaks at the CYS3 initiation site of meiotic recombination in Saccharomyces cerevisiae. EMBO J. 14: 4589-4598.
12. DE WIND, N., M. DEKKER, A. BERNS, M. RADMAN and H. TE RIELE, 1995 Inactivation of the mouse MSH2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. Cell 82: 321-330.
13. DEVEREUX, J., P. HAEBERLI and O. SMITHIES, 1984 A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 16: 7025-7042.
14. DRUMMOND, J. T., G. M. LI, M. J. LONGLEY and P. MODRICH, 1995 Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells. Science 268: 1909-1912.
15. EDELMANN, W., P. E. COHEN, M. KANE, K. LAU, B. MORROW et al., 1996 Meiotic pachytene arrest in MLH1-deficient mice. Cell 85: 1125-1134.
16. FAN, J. B., D. GROTHUES and C. L. SMITH, 1991 Alignment of Sfi I sites with the Not I restriction map of Schizosaccharomyces pombe genome. Nucleic Acids Res. 19: 6289-6294.
17. FANG, W-H., and P. MODRICH, 1993 Human strand-specific mismatch repair occurs by bidirectional mechanisms similar to that of the bacterial reaction. J. Biol. Chem. 268: 11838-11844.
18. FISHEL, R., M. K. LESCOE, M. R. S. RAO, N. G. COPELAND, N. A. JENKINS et al., 1993 The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 75: 1027-1038.
19. FLECK, O., H. MICHAEL and L. HEIM, 1992 The swi4 gene of Schizosaccharomyces pombe encodes a homologue of mismatch repair enzymes. Nucleic Acids Res. 20: 2271-2278.
20. FLECK, O., C. RUDOLPH, A. ALBRECHT, A. LORENTZ, P. SCHÄR et al., 1994 The mutator gene swi8 effects specific mutations in the mating-type region of Schizosacchromyces pombe. Genetics 138: 621-632.
21. FLECK, O., P. SCHÄR and J. KOHLI, 1994 Identification of two mismatch-binding activities in protein extracts of Schizosaccharomyces pombe. Nucleic Acids Res. 22: 5289-5295.
22. GRIMM, C., J. KOHLI, J. MURRAY and K. MAUNDRELL, 1988 Genetic engineering of Schizosaccharomyces pombe. A system for gene disruption and replacement using the ura4 gene as selectable marker. Mol. Gen. Genet. 215: 81-86.
23. GUTZ, H., 1971 Site specific induction of gene conversion in Schizosaccharomyces pombe. Genetics 69: 317-337.
24. GUTZ, H., H. HESLOT, U. LEUPOLD and N. LOPRIENO, 1974 Schizosaccharomyces pombe, pp. 395-446 in Handbook of Genetics, Vol. 1, edited by R. C. KING. Plenum Press, New York.
25. HOHEISEL, J. D., E. MAIER, R. MOTT, L. MCCARTHY, A. V. GRIGORIEV et al., 1993 High resolution cosmid and P1 maps spanning the 14 Mb genome of the fission yeast S. pombe. Cell 73: 109-120.
26. HOLMES, J. J., S. CLARK and P. MODRICH, 1990 Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines. Proc. Natl. Acad. Sci. USA 87: 5837-5841.
27. ITO, H., Y. FUKUDA, K. MURATA and A. KIMURA, 1983 Transformation of intact cells treated with alkali cations. J. Bacteriol. 153: 487-493.
28. KOHLI, J., P. MUNZ, R. AEBI, H. AMSTUTZ, C. GYSLER et al., 1984 Interallelic and intergenic conversion in three serine tRNA genes of Schizosaccharomyces pombe. Cold Spring Harbor Symp. Quant. Biol. 49: 31-40.
29. KRAMER, W., B. KRAMER, M. S. WILLIAMSON and S. FOGEL, 1989 Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: homology of PMS1 to prokaryotic MutL and HexB. J. Bacteriol. 171: 5339-5346.
30. LEA, D. E., and C. A. COULSON, 1949 The distribution of the number of mutants in bacterial populations. J. Genet. 49: 264-285.
31. LEACH, F. S., N. C. NICOLAIDES, N. PAPADOPOULOS, B. LIU, J. JEN et al., 1993 Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 75: 1215-1225.
32. LI, G-M., and P. MODRICH, 1995 Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs. Proc. Natl. Acad. Sci. USA 92: 1950-1954.
33. LIU, J., T-C. WU and M. LICHTEN, 1995 The loaction and structure of double-strand DNA breaks induced during yeast meiosis: evidence for a covalently linked DNA-protein intermediate. EMBO J. 14: 4599-4608.
34. LURIA, S. E., and M. DELBRUCK, 1943 Mutations of bacteria from virus sensitivity to virus resistance. Genetics 28: 491-511.
35. MAIER, E., J. D. HOHEISEL, L. MCCARTHY, R. MOTT, A. V. GRIGORIEV et al., 1992 Complete coverage of the Schizosaccharomyces pombe genome in yeast artificial chromosomes. Nature Genet. 1: 273-277.
36. MARSISCHKI, G. T., N. FILOSI, M. F. KANT, and R. KOLODNER, 1996 Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair. Genes Dev. 10: 407-420.
37. MIRET, J. J., M. G. MILLA and R. S. LAHUE, 1993 Characterization of a DNA mismatch-binding activity in yeast extracts. J. Biol. Chem. 268: 3507-3513.
38. MODRICH, P., 1991 Mechanisms and biological effects of mismatch repair. Annu. Rev. Genet. 25: 229-253.
39. MUNZ, P., 1975 On some properties of five imitator alleles in Schizosaccharomyces pombe. Mutat. Res. 29: 155-157.
40. NEW, L., K. LIU and G. F. GROUSE, 1993 The yeast gene MSH3 defines a new class of eukaryotic MutS homologues. Mol. Gen. Genet. 239: 97-108.
41. NICOLAIDES, N. C., N. PAPADOPOULOS, B. LIU, Y-F. WEI, K. C. CARTER et al., 1994 Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature 371: 75-80.
42. NICOLAS, A., and T. D. PETES, 1994 Polarity of meiotic gene conversion in fungi: contrasting views. Experientia 50: 242-252.
43. PALOMBO, F., P. GALLINARI, I. IACOARINO, T. LETTIERI, M. HUGHES et al., 1995 GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells. Science 268: 1912-1914.
44. PAPADOPOULOS, N., N. C. NICOLAIDES, Y-F. WEI, S. M. RUBEN, K. C. CARTER et al., 1994 Mutation of a mutL homolog in hereditary colon cancer. Science 263: 1625-1629.
45. PETES, T. D., R. E. MALONE and L. S. SYMINGTON, 1991 Recombination in yeast, pp. 407-521 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Genome Dynamics, Protein Synthesis and Energetics, Vol. 1, edited by J. R. BROACH, E. JONES and J. PRINGLE, Gold Spring Harbor Press, Gold Sring Harbor, NY.
46. PONTICELLI, A. S., E. P. SENA and G. R. SMITH, 1988 Genetic and physical analysis of the M26 recombination hotspot of Schizosaccharomyces pombe. Genetics 119: 491-497.
47. PRABHALA, G., G. H. ROSENBERG and N. F. KÄUFER, 1992 Architectural features of pre-mRNA introns in the fission yeast Schizosaccharomyces pombe. Yeast 8: 171-182.
48. PROLLA, T. A., D-M. CHRISTIE and R. M. LISKAY, 1994a Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene. Mol. Cell. Biol. 14: 407-415.
49. PROLIA, T. A., Q. PANG, E. ALANI, R. D. KOLODNER and R. M. LISKAY, 1994b MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast. Science 265: 1091-1093.
50. PROUDFOOT, N. J., and G. G. BROWNLEE, 1976 Non-coding region sequences in eucaryotic messenger RNA. Nature 263: 211-214.
51. PRUDHOMME, M., B. MARTIN, V. MEJEAN and J. CLAVERYS, 1989 Nucleotide sequence of the Streptococcus pneumoniae hexB mismatch repair gene: homology of HexB to MutL of Salmonella typhimurium and to PMS1 of Saccharomyces cerevisiae. J. Bacteriol. 171: 5332-5338.
52. RADMAN, M., and R. WAGNER, 1993 Mismatch recognition in chromosomal interactions and speciation. Chromosoma 102: 369-373.
53. REENAN, R. A. G., and R. D. KOLODNER, 1992a Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins. Genetics 132: 963-973.
54. REENAN, R. A. G., and R. D. KOLODNER, 1992b Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions. Genetics 132: 975-985.
55. SANCAR, A., and J. E. HEARST, 1993 Molecular matchmakers. Science 259: 1415-1420.
56. SCHÄR, P., and J. KOHLI, 1993 Marker effects of G to C transversions on intragenic recombination and mismatch repair in Schizosaccharomyces pombe. Genetics 133: 825-835.
57. SCHÄR, P., and J. KOHLI, 1994 Preferential strand transfer and hybrid DNA formation at the recombination hotspot ade6-M26 of Schizosaccharomyces pombe. EMBO J. 13: 5212-5219.
58. SCHÄR, P., P. MUNZ and J. KOHLI, 1993 Meiotic mismatch repair quantified on the basis of segregation patterns in Schizosaccharomyces pombe. Genetics 133: 815-824.
59. SMITH, G. R., 1994 Hotspots of homologous recombination. Experientia 50: 234-241.
60. SNOW, R., 1979 Maximum likelihood estimation of linkage and interference from tetrad data. Genetics 92: 231-245.
61. STRAND, M., T. A. PROLLA, R. M. LISKAY and T. D. PETES, 1993 Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature 365: 274-276.
62. SZANKASI, P., and G. R. SMITH, 1995 A role for Exonuclease I from S. pombe in mutation avoidance and mismatch correction. Science 267: 1166-1169.
63. SZANKASI, P., W. D. HEYER, P. SCHUCHERT and J. KOHLI, 1988 DNA sequence analysis of the ade6 gene of Schizosaccharomyces pombe. Wild-type and mutant alleles including the recombination hot spot ade6-M26. J. Mol. Biol. 204: 917-925.
64. SZOSTAK, J. W., T. L. ORR-WEAVER, R. J. ROTHSTEIN and F. W. STAHL, 1983 The double-strand-beak repair model for recombination. Cell 33: 25-35.
65. TSUI, H-C. T., B. S. MANDAVILLI and M. E. WINKLER, 1992 Nonconserved segment of the MutL protein from Escherichia coli K-12 and Salmonella typhimurium. Nucleic Acids Res. 20: 2379.
66. VARLET, I., M. RADMAN and P. BROOKS, 1990 DNA mismatch repair in Xenopus egg extracts: repair efficiency and DNA repair synthesis for all single base-pair mismatches. Proc. Natl. Acad. Sci. USA 87: 7883-7887.
67. WILLIAMSON, M. S., J. C. GAME and S. FOGEL, 1985 Meiotic gene conversion mutants in Saccharomyces cerevisiae. I. Isolation and characterization of PMS1-1 and PMS2-2. Genetics 110: 609-646.
68. WRIGHT, A. P. H., K. MAUNDRELL and S. SHALE, 1986 Transformation of Schizosaccharomyces pombe by non-homologous unstable integration of plasmids in the genome. Curr. Genet. 10: 503-508.