Recombinant human erythropoietin as adjuvant treatment for autologous blood donation in elective surgery with large blood needs (≤5 units): A randomized study

Transfusion

Volumn 37, Issue 7, 1997, Pages 708-714

  De Pree, C ^a   Mermillod, B ^a   Hoffmeyer, P ^a   Beris, P ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN;

ADULT; AGED; ARTICLE; BLOOD AUTOTRANSFUSION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ELECTIVE SURGERY; ERYTHROCYTE COUNT; ERYTHROPOIESIS; FEMALE; HUMAN; IRON BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PREOPERATIVE TREATMENT; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

EID: 0030852719     PISSN: 00411132     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1537-2995.1997.37797369446.x     Document Type: Article

References (17)

1. Williamson L. Homologous blood transfusion: the risks and alternatives. Br J Haematol 1994;88:451-8.
2. Practice strategies for elective red blood cell transfusion. American College of Physicians. Ann Intern Med 1992;116:403-6.
3. Beris P, Mermillod B, Levy G, et al. Recombinant human erythropoietin as adjuvant treatment for autologous blood donation. A prospective study. Vox Sang 1993;65:212-8.
4. Kickler TS, Spivak JL. Effect of repeated whole blood donations on serum immunoreactive erythropoietin levels in autologous donors. JAMA 1988;260:65-7.
5. Nadler SB, Hidalgo JU, Bloch TE. Prediction of blood volume in normal human adults. Surgery 1962;51:224-32.
6. Dixon WJ, ed. BMDP Statistical Software, Berkeley: University of California, 1990.
7. Krantz SB. Erythropoietin. Blood 1991;77:419-34.
8. Goodnough LT, Rudnick S, Price TH, et al. Increased preoperative collection of autologous blood with recombinant human erythropoietin therapy. N Engl J Med 1989;321:1163-8.
9. Price TH, Goodnough LT, Vogler WR, et al. The effect of recombinant human erythropoietin on the efficacy of autologous blood donation in patients with low hematocrits: a multicenter, randomized, double-blind, controlled trial. Transfusion 1996;36:29-36.
10. Mercuriali F, Gualtieri G, Sinigaglia L, et al. Use of recombinant human erythropoietin to assist autologous blood donation by anemic rheumatoid arthritis patients undergoing major orthopedic surgery. Transfusion 1994;34:501-6.
11. Brown EB Jr, Dubach R, Moore CV. Studies in iron transportation and metabolism. XI. Critical analysis of mucosal block by large doses of inorganic iron in human subjects. J Lab Clin Med 1958;52:335-42.
12. Fairbanks VF, Beutler E. Iron metabolism. In: Beutler E, Lichtman M, Coller BS, Kipps TJ, eds. Williams hematology. 5th ed. New York: McGraw-Hill, 1995:369-80.
13. Mercuriali F, Zanella A, Barosi G, et al. Use of erythropoietin to increase the volume of autologous blood donated by orthopedic patients. Transfusion 1993;33:55-60.
14. Goodnough LT, Verbrugge D, Marcus RE, Goldberg V. The effect of patient size and dose of recombinant human erythropoietin therapy on red blood cell volume expansion in autologous blood donors for elective orthopedic operation. J Am Coll Surg 1994;179:171-6.
15. Goodnough LT, Price TH, Friedman KD, et al. A phase III trial of recombinant human erythropoietin therapy in nonanemic orthopedic patients subjected to aggressive removal of blood for autologous use: dose, response, toxicity, and efficacy. Transfusion 1994;34:66-71.
16. Etchason J, Petz L, Keeler E, et al. The cost effectiveness of preoperative autologous blood donations. N Engl J Med 1995;332:719-24.
17. Goodnough LT, Price TH, Rudnick S, Soegiarso RW. Preoperative red cell production in patients undergoing aggressive autologous blood phlebotomy with and without erythropoietin therapy. Transfusion 1992;32:441-5.