Raised erythrocyte polyamine levels in non-insulin-dependent diabetes mellitus with great vessel disease and albuminuria

Diabetes Research and Clinical Practice

Volumn 37, Issue 1, 1997, Pages 15-20

  Seghieri, Giuseppe ^a   Anichini, Roberto ^a   Ciuti, Mila ^b   Gironi, Alfredo ^b   Bennardini, Federico ^c   Franconi, Flavia ^c  

^a Diabetes Unit   (Italy)

^b University of Sassari ^*  (Italy)

^c UNIVERSITY OF SASSARI   (Italy)

Author keywords

Albuminuria; Macroangiopathy; Non insulin dependent diabetes mellitus; Polyamines

Indexed keywords

ALBUMIN; POLYAMINE; SPERMIDINE; SPERMINE;

ADULT; ARTICLE; CELL LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETIC MICROANGIOPATHY; ERYTHROCYTE; FEMALE; HUMAN; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; POLYAMINE METABOLISM; PROTEINURIA;

ALBUMINURIA; ARTERIAL OCCLUSIVE DISEASES; BLOOD PRESSURE; CHOLESTEROL; CHOLESTEROL, HDL; CORONARY DISEASE; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; ERYTHROCYTES; FEMALE; HUMANS; ISCHEMIC ATTACK, TRANSIENT; MALE; MIDDLE AGED; POLYAMINES; SPERMIDINE; SPERMINE; TRIGLYCERIDES;

EID: 0030852215     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8227(97)00050-8     Document Type: Article

References (23)

1. J. Janne, H. Poso, A. Raina, Polyamines in rapid growth and cancer, Biochim. Biophys. Acta 473 (1970) 241-293.
2. L. Persson, I. Holm, L. Stjernberg, O. Heby, Regulation of polyamine synthesis in mammalian cells, in: V. Zappia, A.E. Pegg (Eds.), Progress in Polyamine Research, Plenum Press, New York, 1988, pp. 261-271.
3. O. Heby, Role of polyamines in the control of cell proliferation and differentiation, Differentiation 19 (1981) 1-20.
4. J-Ph. Moulinoux, D. Delamaire, B. Beau, et al., Diagnosit value of erythrocyte-free polyamines and histaminemia in malignant hepatic tumors and in liver cyrrhosis, Clin. Chim. Acta 145 (1985) 77-87.
5. G. Seghieri, A. Gironi, P. Mammini, et al., Erythrocyte spermidine levels in IDDM patients, Diabetes Care 15 (1992) 343-345.
6. G. Seghieri, A. Gironi, M. Niccolai, et al., Serum spermidine oxidase activity in patients with insulin-dependent diabetes mellitus and microvascular complications, Acta Diabetolol. Lat. 27 (1990) 303-308.
7. S.B. Pedersen, A. Flyvberg, H. Gronbaek, B. Richelsen, Increased ornithine decarboxylase activity in kidneys undergoing hypertrophy in experimental diabetes, Mol. Cell Endocrinol. 86 (1992) 67-72.
8. S.B. Pedersen, S.F. Bjorn, B. Richelsen, A. Flyvberg, Inhibition of renal ornithine decarboxilase activity fails to reduce kidney size and urinary albumin excretion in diabetic rats with manifest kidney hypertrophy, Mol. Cell Endocrinol. 107 (1995) 123-128.
9. M-A. Gall, P. Rossing, P. Sk∅tt, et al., Prevalence of micro- and macroalbuminuria, arterial hypertension, retinopathy and large vessel disease in European type 2 (non-insulin-dependent) diabetic patients, Diabetologia 34 (1991) 655-661.
10. R.G. Nelson, D.J. Petitt, M.J. Carraher, H.R. Baird, W.C. Knowler, Effect of proteinuria on mortality in NIDDM, Diabetes 37 (1988) 1499-1504.
11. C.E. Mogensen, Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes, N. Engl. J. Med. 310 (1984) 356-360.
12. + antiport activity and cell growth in cultured skin fibroblasts of IDDM patients with nephropathy, Diabetes 41 (1992) 1239-1246.
13. National Diabetes Data Group, Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance, Diabetes 28 (1979) 1039-1057.
14. R.J. Jarrett, H. Keen, W. Grabauskas, The WHO Multinational Study of Vascular disease in Diabetes. 1 General description, Diabetes Care 2 (1979) 175-186.
15. H. Keen, R.J. Jarrett, The WHO Multinational Study of Vascular disease in Diabetes. 2 Macrovascular disease prevalence, Diabetes Care 2 (1979) 187-195.
16. G. Seghieri, G. Bartolomei, L.A. De Giorgio, Plasma fibronectin in diabetic retinopathy and macroangiopathy, Diabete Metab. 12 (1986) 186-190.
17. SAS Institute, SAS/STAT Guide for Personal Computers. Version 6 Edition. SAS Institute, Cary, NC, 1987.
18. T. Deckert, B. Feldt-Rasmussen, K. Borch-Johnsen, T. Jensen, A. Kofoed-Enevoldsen, Albuminuria reflects widespread vascular damage. The Steno hypothesis, Diabetologia 32 (1989) 219-226.
19. M. Lorenzi, D.F. Montisano, S. Toledo, A. Barrieux, High glucose and DNA damage in endothelial cells, J. Clin. Invest. 77 (1986) 322-325.
20. T. Shiba, T. Inoguchi, J.R. Sportsman, W.F. Heath, S. Bursell, G.L. King, Correlation of diacylglycerol level and protein kinase C activity in rat retina to retinal circulation, Am. J. Physiol. 265 (1993) E783-E793.
21. P.A. Craven, F.R. DeRubertis, Protein kinase C is activated in glomeruli from streptozotocin diabetic rats, J. Clin. Invest. 83 (1989) 1667-1675.
22. M.S. Moruzzi, G. Piccinini, B. Tadolini, M.G. Monti, B. Barbiroli, G. Mazzetti, Effect of polyamines on protein kinase C activation process, in: V. Zappia, A.E. Pegg, (Eds.), Progress in Polyamine Research, Plenum Press, New York, 1988, pp. 469-480.
23. M. Marx, G. Trittenwein, C. Aufricht, H. Hoeger, B. Lubec, Agmatine and spermidine reduce collagen accumulation in kidneys of diabetic db/db mice, Nephron 69 (1995) 155-158.