Effect of feeding, fasting, and diabetes on liver glycogen synthase activity, protein, and mRNA in rats

Diabetologia

Volumn 40, Issue 7, 1997, Pages 758-763

  Gannon, M C ^a,b,c   Nuttall, F Q ^a,c  

^a VA MEDICAL CENTER   (United States)

^b Depts of Food Science and Nutrition   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Diabetes mellitus; Glycogen; Glycogen synthase; mRNA; Phosphorylase; Rats; Ribonuclease protection assay; Western blotting

Indexed keywords

GLUCOSE; GLYCOGEN SYNTHASE; MESSENGER RNA; PHOSPHORYLASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIET RESTRICTION; ENZYME ACTIVITY; FEEDING; GLUCOSE BLOOD LEVEL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

ANALYSIS OF VARIANCE; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; EATING; FASTING; GLYCOGEN SYNTHASE; LIVER; LIVER GLYCOGEN; MALE; PHOSPHORYLASES; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE VALUES; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0030851975     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250050746     Document Type: Article

References (33)

1. Niewoehner CB, Nuttall FQ (1986) Mechanism of stimulation of liver glycogen synthesis by fructose in alloxan diabetic rats. Diabetes 35(6): 705-711
2. Gold AH (1970) The effect of diabetes and insulin on liver glycogen synthetase activation. J Biol Chem 245: 903-905
3. Bahnak BR, Gold AH (1982) Effects of alloxan diabetes on the turnover of rat liver glycogen synthase. Comparison with liver phosphorylase. J Biol Chem 257(15):8775-8780
4. Hornbrook KR (1970) Synthesis of liver glycogen in starved alloxan diabetic rats. Diabetes 19: 916-923
5. Akatsuka A, Singh TJ, Huang KP (1983) Comparison of the liver glycogen synthase from normal and streptozotocin-induced diabetic rats. Arch Biochem Biophys 220(2):426-434
6. Steiner DF, Rauda V, Williams RH (1961) Effects of insulin, glucagon, and glucocorticoids upon hepatic glycogen synthesis from uridine diphosphate glucose. J Biol Chem 236: 299-304
7. Kreutner W, Goldberg ND (1967) Dependence on insulin of the apparent hydrocortisone activation of hepatic glycogen synthetase. Proc Natl Acad Sci USA 58: 1515-1519
8. Miller TB, Vicalvi JJ, Garnache AK (1981) Alteration of hepatic glycogen synthase phosphatase activity by insulin deficiency. Am J Physiol 240:E539-E543
9. Bahnak BR, Gold AH (1982) Isolation and characterization of liver glycogen synthase from diabetic rats. Arch Biochem Biophys 213(2):492-503
10. Nuttall FQ, Gannon MC (1994) Liver glycogen synthase activity, protein mass and mRNA expression in liver from normal fed and fasted and diabetic fed and fasted rats. FASEB/ASBMB meeting, Washington, DC, May 21-25, 1994. Page 11, program addendum. Abst #2 B21
11. 14C] glucose. Biochim Biophys Acta 582: 543-547
12. Nuttall FQ, Gannon MC (1989) An improved assay for hepatic glycogen synthase in liver extracts with emphasis on synthase R. Analyt Biochem 178: 311-319
13. Gilboe DP, Larson KL, Nuttall FQ (1972) A radioactive method for the assay of glycogen phosphorylases. Analyt Chem 47: 20-27
14. Zak B, Cohen J (1961) Automatic analysis of tissue culture proteins with stable Folin reagents. Clin Chim Acta 6: 665-670
15. Carr RS, Neff JM (1984) Quantitative semi-automated enzymatic assay for tissue glycogen. Comp Biochem Physiol 77B(3):447-449
16. Chomczynski P (1993) A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. BioTechniques 15: 532-537
17. Chomczynski P, Sacchi N (1987) Single step methods for RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction. Analyt Biochem 162: 156-159
18. Sarkar G, Yoon H-S, Sommer SS (1992) Dideoxy fingerprinting (ddF): a rapid and efficient screen for the presence of mutations. Genomics 13: 441-443
19. Bai G, Zhang Z, Werner R, Nuttall FQ, Tan AWH, Lee EYC (1990) The primary structure of rat liver glycogen synthase deduced by cDNA cloning. J Biol Chem 265(14):7843-7848
20. Gannon MC (1993) The effect of oral casein on hepatic glycogen metabolism in fasted rats. Metabolism 42(5):649-653
21. Ercan N, Gannon MC, Nuttall FQ (1994) Liver glycogen synthase, phosphorylase and glycogen concentration in rats given a single glucose load orally. A 24 hour study. Arch Biochem Biophys 315(1):35-40
22. Ercan N, Gannon MC, Nuttall FQ (1994) Incorporation of glycogenin into hepatic proteoglycogen after oral glucose administration. J Biol Chem 269(35):22328-22333
23. Gannon MC, Nuttall FQ (1995) Physiological doses of oral casein affect hepatic glycogen metabolism in normal food-deprived rats. J Nutr 125: 1159-1166
24. Niewoehner C, Nuttall FQ (1995) Glycogen concentration and regulation of synthase activity in rat liver in-vivo. Arch Biochem Biophys 318(2):271-278
25. Tan AWH, Nuttall FQ (1976) Regulation of synthase phosphatase and phosphorylase phosphatase in rat liver. Biochim Biophys Acta 445: 118-130
26. Rao PV, Pugazhenthi S, Khandelwal RL (1995) The effects of streptozotocin-induced diabetes and insulin supplementation on expression of the glycogen phosphorylase gene in rat liver. J Biol Chem 270(42):24955-24960
27. Khandelwal RL, Zinman SM, Zebrowski EJ (1977) The effect of streptozotocin-induced diabetes and of insulin supplementation on glycogen metabolism in rat liver. Biochem J 168: 541-548
28. Giffin BF, Drake RI, Morris RE, Cardell RR (1993) Hepatic lobular patterns of phosphoenolpyruvate carboxykinase, glycogen synthase, and glycogen phosphorylase in fasted and fed rats. J Histochem Cytochem 41(12):1849-1862
29. Wititsuwannakul D, Kim K-H (1979) Immunological studies of liver glycogen synthase. Relative significance of covalent modification and changes in the rate of synthesis and degradation. J Biol Chem 254(9):3562-3569
30. Nur T, Sela I, Webster NJG, Madar Z (1995) Starvation and refeeding regulate glycogen synthase gene expression in rat liver at the post-transcriptional level. J Nutr 125: 2457-2462
31. Tan AWH, Nuttall FQ (1983) Endogenous phosphates on liver glycogen synthase D and synthase I. Studies on the number and location. J Biol Chem 258: 9624-9630
32. 32P] phosphates. J Biol Chem 260(8):4751-4757
33. Fernandez-Novell JM, Arino J, Vilaro S, Guinovart JJ (1992) Glucose induces the translocation and the aggregation of glycogen synthase in rat hepatocytes. Biochem J 281: 433-448