Photo-induced inactivation of dihydroorotate dehydrogenase in dilute aqueous solution

International Journal of Radiation Biology

Volumn 72, Issue 1, 1997, Pages 55-61

  Saha, Abhijit ^a,b  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b SAHA INSTITUTE OF NUCLEAR PHYSICS   (India)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROOROTATE DEHYDROGENASE;

ARTICLE; CONTROLLED STUDY; ENZYME INACTIVATION; ENZYME SUBSTRATE COMPLEX; LIGHT EXPOSURE; MICHAELIS MENTEN KINETICS; NONHUMAN; PHOTOCHEMISTRY; PRIORITY JOURNAL; REACTION TIME;

ENZYME ACTIVATION; OXIDOREDUCTASES; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PHOTOCHEMISTRY; SOLUTIONS; SPECTROMETRY, FLUORESCENCE; ULTRAVIOLET RAYS; WATER;

EID: 0030851962     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530097143536     Document Type: Article

References (22)

1. BENSASSON, R. V., LAND, E. J. and TRUSCOTT, T. J., 1983, Flash Photolysis and Pulse Radiolysis (Oxford: Pergamon).
2. FRIEDMANN, H. C. and KRAKOW, G., 1981, Determination with dihydroorotate dehydrogenase. In Methods in Enzymatic Analysis, edited by H.U. Bergmeyer, 2nd edition Vol. 4, (Verlag, Berlin: Verlag), pp. 1963-1966.
3. FRIEDMANN, H. C. and VENNESLAND, 1960, Crystalline dihydroorotic dehydrogenase. Journal of Biological Chemistry, 235, 1526-1532.
4. GROSSWEINER, L. I., 1976, Photochemical inactivation of enzymes. Current Topics in Radiation Research, 11, 141-199.
5. GROSSWEINER, L. I., KALUSKAR, A. G. and BAUCHER, J. F., 1976, Flash photolysis of enzymes. International Journal of Radiation Biology, 29, 1-16.
6. HEELIS, P. F., PARSONS, B. J., PHILLIPS, G. O. and MCKELLER, J. F., 1978, A laser flash photolysis study of the nature of flavin mononucleotide triplet states and the reactions of the neutral form with amino acids. Photochemistry and Photobiology, 28, 169-173.
7. JAWAD, H. H. and WATT, D. E., 1986, Physical mechanism for inactivation of metallo-enzymes by characteristic X-rays. International Journal of Radiation Biology, 50, 665-674.
8. KOWALSKA, M. A., LEWANDOWSKA, S., PUCHALA, M. and LEYKO, W., 1981, Changes in the tryptophan fluorescence in gamma-irradiated human hemoglobin. International Journal of Radiation Biology, 39, 21-30.
9. KUHN, H. J., BRASLAVSKY, S. E. and SCHMIDT, R., 1989, Chemical actinometry. Pure and Applied Chemistry, 61, 187-210.
10. LEHNINGER, A. L., 1987, Principles of Biochemistry (New York: Worth), pp. 467-505.
11. MILLER, R. N. and MASSEY, V., 1965, Dihydroorotate dehydrogenase (I) properties of the enzymes, (II) oxidation and reduction of cytochrome C. Journal of Biological Chemistry, 240, 1453-1465.
12. NELSON, C. A. and HANDLER, P., 1968, Preparation of bovine xanthine oxidase and the subunit structures of some iron flavoproteins. Journal of Biological Chemistry, 243, 5368-5373.
13. SAHA, A., MANDAL, P. C. and BHATTACHARYYA, S. N., 1991, Radiation-induced changes in flavin fluorescence of dihydroorotate dehydrogenase. International Journal of Radiation Biology, 60, 769-778.
14. SAHA, A., MANDAL, P. C. and BHATTACHARYYA, S. N., 1992, Radiation-induced inactivation of dihydroorotate dehydrogenase in dilute aqueous solution. Radiation Research, 132, 7-12.
15. SAHA, A., MANDAL, P. C. and BHATTACHARYYA, S. N., 1993, Tyrosine residues in unirradiated and γ-irradiated dihydroorotate dehydrogenase: fluorimetric and second-derivative absorption spectrophotometric studies. International Journal of Radiation Biology, 63, 557-564.
16. SAHA, A., MANDAL, P. C. and BHATTACHARYYA, S. N., 1995, Radiation-induced inactivation of enzymes - A review. Radialion Physics and Chemistry, 46, 123-145.
17. SHIMIZU, O. and IMAKUVO, K., 1977, New emission hand of tyrosine induced by interaction with phosphate ions. Photochemistry and Photobiology, 26, 541-543.
18. TOLLIN, G. and HAZZARD, J. T., 1991, Intra- and intermolecular electron transfer processes in redox proteins. Archives of Biochemistry and Biophysics, 287, 1-7.
19. TU, S. C. and MCCORMICK, D., 1973, Photoinactivation of porcine D-amino acid oxidase with flavin adenine dinucleotide. The Journal of Biological Chemistry, 248, 6339-6347.
20. VILJOEN, B., DUBERY, I. A. and SCHABORT, J. C., 1987, The effect of γ-radiation on the NADP-malic enzyme from mango fruit, Mangifera indica. II. Kinetic and regulatory properties. International Journal of Biochemistry, 19, 837-841.
21. VISSER, A. J. W. G., MULLER, F. and VAN VOORST, J. D. W., 1977, Laser flash photolysis of flavins and some flavoproteins. Biochemical and Biophysical Research Communication, 77, 1135-1142.
22. WALSH, C., 1984, Biochemistry of naturally occurring deazaflavin coenzymes. In Flarins and Flavoproteins, edited by R. C. Bray, P. C. Engel, and S. G. Mayhew (New York: de Gruyter), pp. 723-735.