Pulmonary fungal infections in immunocompromised children

Current Opinion in Pediatrics

Volumn 9, Issue 3, 1997, Pages 213-218

  Shenep, Jerry L ^a,b   Flynn, Patricia M ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; ANTIFUNGAL AGENT; COTRIMOXAZOLE; FLUCONAZOLE; FLUCYTOSINE; ITRACONAZOLE;

CANCER; CANDIDIASIS; CRYPTOCOCCOSIS; FUSARIUM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE DEFICIENCY; INFECTION PREVENTION; LUNG ASPERGILLOSIS; LUNG INFECTION; MUCORMYCOSIS; MYCOSIS; PEDIATRICS; PHAEOHYPHOMYCOSIS; PNEUMOCYSTOSIS; PRIORITY JOURNAL; REVIEW; TRICHOSPORON;

ANTIBIOTIC PROPHYLAXIS; ANTICARCINOGENIC AGENTS; ANTIFUNGAL AGENTS; CHILD; HIV INFECTIONS; HUMANS; IMMUNOCOMPROMISED HOST; IMMUNOSUPPRESSION; LUNG DISEASES, FUNGAL; NEOPLASMS; NEUTROPENIA; OPPORTUNISTIC INFECTIONS; PEDIATRICS; PNEUMONIA;

EID: 0030851880     PISSN: 10408703     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008480-199706000-00004     Document Type: Review

References (34)

1. Hughes WT: Fatal infections in childhood leukemia. Am J Dis Child 1971, 122:283-287.
2. Heurlin N, Bergström S-E, Winiarski J, Ringden O, Ljungman P, Lönnqvist B, Andersson J: Fungal pneumonia: the predominant lung infection causing death in children undergoing bone marrow transplantation. Acta Paediatr 1996, 85:168-172. An analysis of pulmonary infections in 20 children undergoing bone marrow transplantation. This study included analysis of the diagnostic value of fiberoptic bronchoscopy.
3. Stover DE, Kaner RJ: Pulmonary complications in cancer patients. CA Cancer J Clin 1996, 46:303-320. This review of pulmonary complications in patients with cancer provides a summary of the available information and decision-making trees for the management of pneumonia in this population.
4. Davies SF: Fungal pneumonia. Med Clin North Am 1994, 78:1049-1065.
5. Edman JC, Kovacs JA, Masur H, Santi DV, Elwood HJ, Sogin ML: Ribosomal RNA sequence shows Pneumocystis carinii to be a member of the fungi. Nature 1988, 334:519-522.
6. Ypman-Wong MF, Fonzi WA, Sypherd PS: Fungus-specific translation elongation factor-3 gene in Pneumocystis carinii. Infect Immun 1992, 60:4140-4145.
7. Bradsher RW: Histoplasmosis and blastomycosis. Clin Infect Dis 1996, 22(suppl 2):S102-S111.
8. Walsh TJ, Gonzalez C, Lyman CA, Chanock SJ, Pizzo PA: Invasive fungal infections in children: recent advances in diagnosis and treatment Adv Pediatr Infect Dis 1995, 11:187-290. A comprehensive review of fungal infections in children with emphasis on the immunocompromised host. This review contains 418 references.
9. Flynn PM, Marina NM, Rivera GK, Hughes WT: Candida tropicalis infections in children with leukemia. Leuk Lymphoma 1993, 10:369-376.
10. Flynn PM, Shenep JL, Crawford R, Hughes WT: Use of abdominal computed tomography for identifying disseminated fungal infection in pediatric cancer patients. Clin Infect Dis 1995, 20:964-970.
11. Murray JF: Pulmonary complications of HIV infection. Annu Rev Med 1996, 47:117-126.
12. Su TH, Martin WJ II: Pathogenesis and host response in Pneumocystis carinii pneumonia. Annu Rev Med 1994, 45:261-272.
13. Beyer J, Schwartz S, Heinemann V, Siegert W: Strategies in prevention of invasive pulmonary aspergillosis in immunosuppressed or neutropenic patients. Antimicrob Agents Chemother 1994, 38:911-917.
14. Meyer RO, Rosen P, Armstrong D: Phycomycosis complicating leukemia and lymphoma. Ann Intern Med 1972, 77:871-679.
15. Tashiro T, Nagai H, Nagaoka H, Goto Y, Kamberi P, Nasu M: Trichosporon beigelii pneumonia in patients with hematologic malignancies. Chest 1995, 108:190-195.
16. Brown MJ, Miller RR, Müller NL: Acute lung disease in the immunocompromised host: CT and pathologic examination findings. Radiology 1994, 190:247-254.
17. Yu VL, Muder RR, Poorsattar A: Significance of isolation of Aspergillus from the respiratory tract in diagnosis of invasive pulmonary aspergillosis: results of a three-year prospective study. Am J Med 1986, 81:249-254.
18. Stokes DC, Shenep JL, Parham D, Bozeman PM, Marienchek W, Mackert PW: Role of flexible bronchoscopy in the diagnosis of pulmonary infiltrates in pediatric patients with cancer. J Pediatr 1989, 115:561-567.
19. Frankel LR, Smith DW, Lewiston NJ: Bronchoalveolar lavage for diagnosis of pneumonia in the immunocompromised child, Pediatr 1988, 81:785-788.
20. Janzen DL, Adler BD, Padley SP, Müller NL: Diagnostic success of bronchoscopic biopsy in immunocompromised patients with acute pulmonary disease: predictive value of disease distribution as shown on CT. AJR Am J Roentgenol 1993, 160:21-24.
21. Ratjen F, Costabel U, Havers W: Differential cytology of bronchoalveolar lavage fluid in immunosuppressed children with pulmonary infiltrates. Arch Dis Child 1996, 74:507-511.
22. Shorter NA, Ross III AJ, August C, Schnaufer L, Zeigler M, Templeton, Jr JM, Bishop H, O'Neill Jr JA: The usefulness of open-lung biopsy in the pediatric bone marrow transplant population. J Pediatr Surg 1988, 23:533-537.
23. Early GL, Williams TE, Kilman JW: Open lung biopsy. Its effects on therapy in the pediatric patient Chest 1985, 87:467-469.
24. Ellis ME, Spence D, Bouchama A, Antonius J, Bazarbashi M, Khougeer F, DeVol EB: Open lung biopsy provides a higher and more specific diagnostic yield compared to bronchoalveolar lavage in immunocompromised patients. Scand J Infect Dis 1995, 27:157-162.
25. Young VK, Maghur HA, Luke DA, McGovern EM: Operation for cavitating invasive pulmonary aspergillosis in immunocompromised patients. Ann Thorac Surg 1992, 53:621-624.
26. Temeck BK, Venzon DJ, Moskaluk CA, Pass HI: Thoracotomy for pulmonary mycoses in non-HIV-immunosuppressed patients. Ann Thorac Surg 1994: 58:333-338.
27. Wong K, Waters CM, Walesby RK: Surgical management of invasive pulmonary aspergillosis in immunocompromised patients. Eur J Cardiothorac Surg 1992, 6:138-142.
28. McWhinney PH, Kibbler CC, Hamon MD, Smith OP, Gandhi L, Berger LA, Walesby RK, Hoffbrand AV, Prentice HG: Progress in the diagnosis and management of aspergillosis in bone marrow transplantation: 13 years experience. Clin Infect Dis 1993, 17:397-404.
29. Martino R, Nomdedeu J, Altes A, Sureda A, Brunet S, Martinez C, Domingo-Albos A: Successful bone marrow transplantation in patients with previous invasive fungal infections: report of four cases. Bone Marrow Transplant 1994, 13:265-269.
30. Goodman JL, Winston DJ, Greenfield RA, Chandrasekar PH, Fox B, Kaizer H, Shadduck RK, Shea TC, Stiff P, Friedman DJ, et al.: A controlled trial of fluconazole to prevent fungal infections in patients undergoing bone marrow transplantation. N Engl J Med 1992, 326:845-851.
31. Slavin MA, Osborne B, Adams R, Levenstein MJ, Schoch HG, Feldman AR, Meyers JD, Bowden RA: Efficacy and safety of fluconazole prophylaxis for fungal infections after marrow transplantation: a prospective, randomized, double-blind study. J Infect Dis 1995, 171:1545-1552.
32. Winston DJ, Pakrasi A, Busuttil RW: Fluconazole prophylaxis of fungal infections in liver transplant recipients: results of a placebo-controlled, double-blind trial. Assis, Italy: 9th International Symposium on Infections in the Immunocompromised Host; 1996: abstract #146.
33. Winston DJ, Chandrasekar PH, Lazarus HM, Goodman JL, Silber JL, Horowitz H, Shadduck RK, Rosenfeld CS, Ho WG, Islam MZ, Buell DN: Fluconazole prophylaxis of fungal infections in patients with acute leukemia: results of a randomized placebo-controlled, double-blind, multicenter trial. Ann Intern Med 1993, 118:495-503.
34. Flynn PM, Patrick CC, Baker D, Hughes WT: Fluconazole prophylaxis in pediatric bone marrow transplant recipients: a randomized, blinded trial. Assisi, Italy: 9th International Symposium on Infections in the Immunocompromised Host; 1996: abstract #166.