Relation between blood pH and ionized calcium during acute metabolic alteration of the acid-base balance in vivo

Scandinavian Journal of Clinical and Laboratory Investigation

Volumn 57, Issue 4, 1997, Pages 317-323

  Gaiter, A M ^a,b   Bonfant, G ^a   Manes, M ^a   Belfanti, P ^a   Alloatti, S ^a  

^a Aosta Hospital   (Italy)

^b General Hospital   (Italy)

Author keywords

Acid base imbalance; Bicarbonate; Blood pH; Ionized calcium; Metabolic acidosis; Metabolic alcalosis

Indexed keywords

AMMONIUM CHLORIDE;

ACID BASE BALANCE; ACIDOSIS; ADULT; ALKALOSIS; ARTICLE; BLOOD PH; CALCIUM CELL LEVEL; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; MALE; NORMAL HUMAN; PRIORITY JOURNAL;

EID: 0030851328     PISSN: 00365513     EISSN: None     Source Type: Journal    
DOI: 10.3109/00365519709099405     Document Type: Article

References (19)

1. Siggaard-Andersen O, Thode J, Fogh-Andersen N. What is "ionized calcium"? Scand J Clin Lab Invest 1983; 43 Suppl 165: 11-6.
2. Forman DT, Lorenzo L. Ionized calcium: its significance and clinical usefulness. Ann Clin Lab Sci 1991; 21: 297-304.
3. Fogh-Andersen N, Frederiksen PS, Andersen EA, Thode J. Relation between ionised calcium and pH in infants with acute acid base disturbances. Clin Chim Acta 1983; 130: 357-361.
4. Thode J. Ionized calcium and cyclic AMP in plasma and urine. Biochemical evaluation in calcium metabolic disease. Scand J Clin Lab Invest 1990; 50 Suppl 197: 1-45.
5. Siggaard-Andersen O, Thode J, Wandrup J. The concentration of free calcium ions in the blood plasma: "ionized calcium". In: Siggaard-Andersen O, editor Blood pH, carbon dioxide, oxygen, and calcium-ion. Proc. 5th meeting IFCC EPpH. Copenhagen Denmark, 1981.
6. Bonfant G, Gaiter AM, Belfanti P, Ratibondi S, Alloatti S. La determinazione del calcio libero in nefrologia: aspetti metodologici. Biochimica Clinica 1993; 17: 704-10.
7. Lemann J Jr, Lennon EJ, Goodman ED, Litzow JR, Relman AS. The net balance of acid in subjects given large loads of acid or alkali. J Clin Invest 1965; 44: 507-17.
8. Lemann J Jr, Litzow JR, Lennon EJ. The effects of chronic acid loads in normal man: further evidence for the participation of hone mineral in the defense against chronic metabolic acidosis. J Clin Invest 1966; 45: 1608-14.
9. Lemann J Jr, Litzow JR, Lennon EJ, Kelly OA. Study of the mechanism by which chronic metabolic acidosis augments urinary calcium escretion in man. J Clin Invest 1967; 46: 1318-28.
10. Seamonds B, Towfighi J, Arvan DA. Determination of ionized calcium in serum by use of an ion selective electrode. I Determination of normal values under physiologic conditions, with comments on the effects of food ingestion and hyperventilation. Clin Chem 1972; 18: 155-60.
11. Hugues W, Cohen S, Arvan D, Seamonds B. The effect of the alkaline tide on serum-ionised calcium concentration in man. Digestion 1977; 15: 175-81.
12. Thode J, Fogh-Andersen N, Wimberley PD, Møller Sørensen A, Siggaard-Andersen O. Relation between pH and ionized calcium in vitro and in vivo in man. Scand J Clin Lab Invest 1983; 43 Suppl 165: 79-82.
13. Boink AB, Buckley BM, Christiansen TF, et al. International Federation of Clinical Chemistry (IFCC) scientific division TFCC recommendation. Recommendation on sampling, transport and storage for the determination of the concentration of ionized calcium in whole blood, plasma and serum. Ann Biol Clin 1991; 49: 434-8.
14. Hood VL, Keller U, Haymond MW, Kury D. Systemic pH modifies ketone body production rates and lipolysis in humans. Am J Physiol 1990; 259 (Endocrinol Metab 22): E327-E334.
15. Waugh W. Utility of expressing serum sodium per unit of water in assessing hyponatremia. Metabolism 1969; 18: 706-12.
16. Davenport HW. L'ABC dell'equilibrio acido-base. Piccin Ed Padova Italy. 1973: 43-5.
17. Fogh-Andersen N, Christiansen TF, Komarmy L, Siggaard-Andersen O. Measurement of free calcium ion in capillary blood and serum. Clin Chem 1978; 24: 1545-52.
18. Davenport HW. L'ABC dell'equilibrio acido-base. Padova: Piccin Ed, 1973: 75.
19. Davenport HW. L'ABC dell'equilibrio acido-base. Padova: Piccin Ed, 1973: 73-4.