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Volumn 15, Issue 4, 1997, Pages 349-360

Western immunoblotting and enzymatic activity analysis of cathepsin D in human breast cancer cell lines of different invasive potential. Regulation by 17β-estradiol, tamoxifen and ICI 182,780

Author keywords

Antiestrogens; Breast cancer; Cathepsin D; Estrogen; Invasive potential

Indexed keywords

ANTIESTROGEN; CATHEPSIN D; ESTRADIOL; FULVESTRANT; TAMOXIFEN;

EID: 0030850908     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018489819092     Document Type: Article
Times cited : (20)

References (36)
  • 1
    • 0027400940 scopus 로고
    • Prospective study of the prognostic value of cathepsin D levels in breast cancer cytosol
    • Pujol P, Maudelonde T, Daures JP, et al. 1993, Prospective study of the prognostic value of cathepsin D levels in breast cancer cytosol. Cancer, 71, 2006-12.
    • (1993) Cancer , vol.71 , pp. 2006-2012
    • Pujol, P.1    Maudelonde, T.2    Daures, J.P.3
  • 2
    • 0024436155 scopus 로고
    • Cathepsin D: An important marker predicting metastasis in primary breast cancer
    • Spyratos F, Maudelonde T, Brouillet JP, et al. 1989, Cathepsin D: an important marker predicting metastasis in primary breast cancer. Lancet, 334, 1115-18.
    • (1989) Lancet , vol.334 , pp. 1115-1118
    • Spyratos, F.1    Maudelonde, T.2    Brouillet, J.P.3
  • 3
    • 0026779307 scopus 로고
    • Cathepsin D in breast cancer: A tissue marker associated with metastasis
    • Rochefort H, 1992, Cathepsin D in breast cancer: a tissue marker associated with metastasis. Eur J Cancer, 28A, 1780-3.
    • (1992) Eur J Cancer , vol.28 A , pp. 1780-1783
    • Rochefort, H.1
  • 4
    • 0026530280 scopus 로고
    • Cathepsin D in the malignant progression of neoplastic disease
    • Leto G, Gebbia N, Rausa L and Tumminello FM, 1992, Cathepsin D in the malignant progression of neoplastic disease (review). Anticancer Res, 12, 235-40.
    • (1992) Anticancer Res , vol.12 , pp. 235-240
    • Leto, G.1    Gebbia, N.2    Rausa, L.3    Tumminello, F.M.4
  • 5
    • 0026001074 scopus 로고
    • Estradiol down-regulates the mannose 6-phosphate/insulin-like growth factor-II receptor gene and induces cathepsin D in breast cancer cells: A receptor saturation mechanism to increase the secretion of lysosomal proenzymes
    • Mathieu M, Vignon F, Capony F and Rochefort H, 1991, Estradiol down-regulates the mannose 6-phosphate/insulin-like growth factor-II receptor gene and induces cathepsin D in breast cancer cells: a receptor saturation mechanism to increase the secretion of lysosomal proenzymes. Mol Endocr, 5, 815-22.
    • (1991) Mol Endocr , vol.5 , pp. 815-822
    • Mathieu, M.1    Vignon, F.2    Capony, F.3    Rochefort, H.4
  • 6
    • 0015841295 scopus 로고
    • Increased sialic acid density in surface glycoprotein of transformed and malignant cells: A general phenomenon?
    • Van Beek WP, Smets LA and Emmelot P, 1973, Increased sialic acid density in surface glycoprotein of transformed and malignant cells: a general phenomenon? Cancer Res, 33, 2913-22.
    • (1973) Cancer Res , vol.33 , pp. 2913-2922
    • Van Beek, W.P.1    Smets, L.A.2    Emmelot, P.3
  • 7
    • 0022348139 scopus 로고
    • Cell-mediated extracellular acidification and bone resorption: Evidence for a low pH in resorbing lacunæ and localization of a 100-KD lysosomal membrane protein at the osteoclast ruffled border
    • Baron R, Neff L, Louvard D and Courtoy PJ, 1985, Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunæ and localization of a 100-KD lysosomal membrane protein at the osteoclast ruffled border. J Cell Biol, 101, 2210-22.
    • (1985) J Cell Biol , vol.101 , pp. 2210-2222
    • Baron, R.1    Neff, L.2    Louvard, D.3    Courtoy, P.J.4
  • 8
    • 0027312933 scopus 로고
    • Estrogen and insulin modulation of intracellular insulin-like growth factor binding proteins in human breast cancer cells: Possible involvement in lysosomal hydrolases oversecretion
    • Dubois V, Couissi D, Schonne E, Schneider Y-J, Remacle C and Trouet A, 1993, Estrogen and insulin modulation of intracellular insulin-like growth factor binding proteins in human breast cancer cells: possible involvement in lysosomal hydrolases oversecretion. Biochem Biophys Res Commun, 192, 295-301.
    • (1993) Biochem Biophys Res Commun , vol.192 , pp. 295-301
    • Dubois, V.1    Couissi, D.2    Schonne, E.3    Schneider, Y.-J.4    Remacle, C.5    Trouet, A.6
  • 9
    • 0025690427 scopus 로고
    • Cathepsin D: A protease involved in breast cancer metastasis
    • Rochefort H, Capony F and Garcia M, 1990, Cathepsin D: a protease involved in breast cancer metastasis. Cancer Metastasis Rev, 9, 321-31.
    • (1990) Cancer Metastasis Rev , vol.9 , pp. 321-331
    • Rochefort, H.1    Capony, F.2    Garcia, M.3
  • 10
    • 0025848088 scopus 로고
    • Retinoid acid modulates both invasion and plasma membrane ruffling of MCF-7 human mammary carcinoma cells in vitro
    • Bracke M, Van Larebeke NA, Vyncke BM and Mareel MM, 1991, Retinoid acid modulates both invasion and plasma membrane ruffling of MCF-7 human mammary carcinoma cells in vitro. Br J Cancer, 63, 867-72.
    • (1991) Br J Cancer , vol.63 , pp. 867-872
    • Bracke, M.1    Van Larebeke, N.A.2    Vyncke, B.M.3    Mareel, M.M.4
  • 11
    • 0026249547 scopus 로고
    • Regulation of basement membrane invasiveness in human breast cancer model systems
    • Thompson EW, Lippman ME and Dickson RB, 1991, Regulation of basement membrane invasiveness in human breast cancer model systems. Mol Cell Endocr, 82, C203-C208.
    • (1991) Mol Cell Endocr , vol.82
    • Thompson, E.W.1    Lippman, M.E.2    Dickson, R.B.3
  • 12
    • 0027096659 scopus 로고
    • The nude mouse as an in vivo model for human breast cancer invasion and metastasis
    • Brünner N, Boysen B, Romer J and Spang-Thomsen M, 1993, The nude mouse as an in vivo model for human breast cancer invasion and metastasis. Breast Cancer Res Treat, 24, 257-64.
    • (1993) Breast Cancer Res Treat , vol.24 , pp. 257-264
    • Brünner, N.1    Boysen, B.2    Romer, J.3    Spang-Thomsen, M.4
  • 13
    • 0024439007 scopus 로고
    • r 52,000 cathepsin D and poor prognosis in primary human breast cancer
    • r 52,000 cathepsin D and poor prognosis in primary human breast cancer. Cancer Res, 49, 6008-14.
    • (1989) Cancer Res , vol.49 , pp. 6008-6014
    • Thorpe, S.M.1    Rochefort, H.2    Garcia, M.3
  • 15
    • 0026335139 scopus 로고
    • Prognostic value of total cathepsin D in breast tumors. A possible role in selection of chemoresistant patients
    • Namer M, Ramaioli A, Fontana X, et al. 1991, Prognostic value of total cathepsin D in breast tumors. A possible role in selection of chemoresistant patients. Breast Cancer Res Treat, 19, 85-93.
    • (1991) Breast Cancer Res Treat , vol.19 , pp. 85-93
    • Namer, M.1    Ramaioli, A.2    Fontana, X.3
  • 16
    • 0016426055 scopus 로고
    • A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasma and viruses
    • Russell WC, Newman C and Williamson DH, 1975, A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasma and viruses. Nature, 253, 461-2.
    • (1975) Nature , vol.253 , pp. 461-462
    • Russell, W.C.1    Newman, C.2    Williamson, D.H.3
  • 17
    • 0017610392 scopus 로고
    • Simple and rapid fluorimetric method for DNA microassay
    • Kapuscinski J and Skoczylas B, 1977, Simple and rapid fluorimetric method for DNA microassay. Anal Biochem, 83, 252-7.
    • (1977) Anal Biochem , vol.83 , pp. 252-257
    • Kapuscinski, J.1    Skoczylas, B.2
  • 19
    • 0021710313 scopus 로고
    • A sensitive procedure for determination of cathepsin D: Activity in alveolar and peritoneal macrophages
    • Orlowski M, Orlowski R, Chang JC, Wilk E and Lesser M, 1984, A sensitive procedure for determination of cathepsin D: activity in alveolar and peritoneal macrophages. Mol Cell Biochem, 64, 155-64.
    • (1984) Mol Cell Biochem , vol.64 , pp. 155-164
    • Orlowski, M.1    Orlowski, R.2    Chang, J.C.3    Wilk, E.4    Lesser, M.5
  • 21
    • 0024511276 scopus 로고
    • Peptide mapping by CNBr fragmentation using a sodium dodecyl sulfate-polyacrylamide minigel system
    • Plaxton WC and Moorhead GBG, 1989, Peptide mapping by CNBr fragmentation using a sodium dodecyl sulfate-polyacrylamide minigel system. Anal Biochem, 178, 391-3.
    • (1989) Anal Biochem , vol.178 , pp. 391-393
    • Plaxton, W.C.1    Moorhead, G.B.G.2
  • 22
    • 0028115873 scopus 로고
    • Western blotting and enzymatic activity analysis of cathepsin D in breast tissue and sera of patients with breast cancer and benign breast disease and of normal controls
    • Schultz DC, Bazel S, Wright LM, et al. 1994, Western blotting and enzymatic activity analysis of cathepsin D in breast tissue and sera of patients with breast cancer and benign breast disease and of normal controls. Cancer Res, 54, 48-54.
    • (1994) Cancer Res , vol.54 , pp. 48-54
    • Schultz, D.C.1    Bazel, S.2    Wright, L.M.3
  • 23
    • 0028130332 scopus 로고
    • Specific mannose-6-phosphate receptor-independent sorting of procathepsin D in breast cancer cells
    • Capony F, Braulke T, Rougeot C, Roux S, Montcourrier P and Rochefort H, 1994, Specific mannose-6-phosphate receptor-independent sorting of procathepsin D in breast cancer cells. Exp Cell Res, 215, 154-63.
    • (1994) Exp Cell Res , vol.215 , pp. 154-163
    • Capony, F.1    Braulke, T.2    Rougeot, C.3    Roux, S.4    Montcourrier, P.5    Rochefort, H.6
  • 24
    • 0027476918 scopus 로고
    • The role of cathepsin D in the invasiveness of human breast cancer cells
    • Johnson MD, Torri JA, Lippman ME and Dickson RB, 1993, The role of cathepsin D in the invasiveness of human breast cancer cells. Cancer Res, 53, 873-7.
    • (1993) Cancer Res , vol.53 , pp. 873-877
    • Johnson, M.D.1    Torri, J.A.2    Lippman, M.E.3    Dickson, R.B.4
  • 25
    • 0028281477 scopus 로고
    • Cathepsin D maturation and its stimulatory effect on metastasis are prevented by addition of KDEL retention signal
    • Liaudet E, Garcia M and Rochefort H, 1994, Cathepsin D maturation and its stimulatory effect on metastasis are prevented by addition of KDEL retention signal. Oncogene, 9, 1145-54.
    • (1994) Oncogene , vol.9 , pp. 1145-1154
    • Liaudet, E.1    Garcia, M.2    Rochefort, H.3
  • 26
    • 0027401411 scopus 로고
    • The future of new pure antiestrogens in breast cancer
    • Wakeling AE, 1993, The future of new pure antiestrogens in breast cancer. Breast Cancer Res Treat, 25, 1-9.
    • (1993) Breast Cancer Res Treat , vol.25 , pp. 1-9
    • Wakeling, A.E.1
  • 27
    • 0027279120 scopus 로고
    • MCF7/LCC2 - A 4-hydroxytamoxifen resistant human breast cancer variant that retains sensitivity to the steroidal antiestrogen ICI 182,780
    • Brünner N, Frandsen TL, Holsthansen C, et al. 1993, MCF7/LCC2 - a 4-hydroxytamoxifen resistant human breast cancer variant that retains sensitivity to the steroidal antiestrogen ICI 182,780. Cancer Res, 53, 3229-32.
    • (1993) Cancer Res , vol.53 , pp. 3229-3232
    • Brünner, N.1    Frandsen, T.L.2    Holsthansen, C.3
  • 28
    • 0028267222 scopus 로고
    • Anti-proliferative and antiestrogenic effects of ICI 164,384 and ICI 182,780 in 4-OH-tamoxifen-resistant human breast-cancer cells
    • Coopman P, Garcia M, Brünner N, Derocq D, Clarke R and Rochefort H, 1994, Anti-proliferative and antiestrogenic effects of ICI 164,384 and ICI 182,780 in 4-OH-tamoxifen-resistant human breast-cancer cells. Int J Cancer, 56, 295-300.
    • (1994) Int J Cancer , vol.56 , pp. 295-300
    • Coopman, P.1    Garcia, M.2    Brünner, N.3    Derocq, D.4    Clarke, R.5    Rochefort, H.6
  • 29
    • 0028084758 scopus 로고
    • Investigation of a new pure antiestrogen (ICI 182780) in women with primary breast cancer
    • DeFriend DJ, Howell A, Nicholson RI, et al. 1994, Investigation of a new pure antiestrogen (ICI 182780) in women with primary breast cancer. Cancer Res, 54, 408-14.
    • (1994) Cancer Res , vol.54 , pp. 408-414
    • DeFriend, D.J.1    Howell, A.2    Nicholson, R.I.3
  • 30
    • 0028578217 scopus 로고
    • In vivo stimulation by tamoxifen of cathepsin D RNA level in breast cancer
    • Maudelonde T, Escot C, Pujol P, et al. 1994, In vivo stimulation by tamoxifen of cathepsin D RNA level in breast cancer. Eur J Cancer, 30A, 2049-53.
    • (1994) Eur J Cancer , vol.30 A , pp. 2049-2053
    • Maudelonde, T.1    Escot, C.2    Pujol, P.3
  • 31
    • 0029129987 scopus 로고
    • Intracellular levels and secretion of insulin-like growth factor binding proteins in MCF-7/6, MCF-7/AZ and MDA-MB-231 breast cancer cells. Differential modulation by estrogens in serum-free medium
    • Dubois V, Couissi D, Schonne E, Remacle C and Trouet A, 1995, Intracellular levels and secretion of insulin-like growth factor binding proteins in MCF-7/6, MCF-7/AZ and MDA-MB-231 breast cancer cells. Differential modulation by estrogens in serum-free medium. Eur J Biochem, 232, 47-53.
    • (1995) Eur J Biochem , vol.232 , pp. 47-53
    • Dubois, V.1    Couissi, D.2    Schonne, E.3    Remacle, C.4    Trouet, A.5
  • 32
    • 0029026592 scopus 로고
    • Coexpression of multiple estrogen receptor variant messenger RNAs in normal and neoplastic breast tissues and in MCF-7 cells
    • Pfeffer U, Fecarotta E and Vidali G, 1995, Coexpression of multiple estrogen receptor variant messenger RNAs in normal and neoplastic breast tissues and in MCF-7 cells. Cancer Res, 55, 2158-65.
    • (1995) Cancer Res , vol.55 , pp. 2158-2165
    • Pfeffer, U.1    Fecarotta, E.2    Vidali, G.3
  • 33
    • 0029073127 scopus 로고
    • Specific mutations in the estrogen receptor change the properties of antiestrogens to full agonists
    • Mahfoudi A, Roulet E, Dauvois S, Parker MG and Wahli W, 1995, Specific mutations in the estrogen receptor change the properties of antiestrogens to full agonists. Proc Natl Acad Sci, USA, 92, 4206-10.
    • (1995) Proc Natl Acad Sci, USA , vol.92 , pp. 4206-4210
    • Mahfoudi, A.1    Roulet, E.2    Dauvois, S.3    Parker, M.G.4    Wahli, W.5
  • 34
    • 0027530694 scopus 로고
    • Procathepsin-D cannot autoactivate to cathepsin-D at acid pH
    • Larsen LB, Boisen A and Petersen TE, 1993, Procathepsin-D cannot autoactivate to cathepsin-D at acid pH. FEBS Lett, 319, 54-8.
    • (1993) FEBS Lett , vol.319 , pp. 54-58
    • Larsen, L.B.1    Boisen, A.2    Petersen, T.E.3
  • 35
    • 0026608412 scopus 로고
    • Isolation and characterization of a stable activation intermediate of the lysosomal apartyl protease cathepsin D
    • Conner GE and Richo G, 1992, Isolation and characterization of a stable activation intermediate of the lysosomal apartyl protease cathepsin D. Biochemistry 31, 1142-47.
    • (1992) Biochemistry , vol.31 , pp. 1142-1147
    • Conner, G.E.1    Richo, G.2


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