-
2
-
-
0025000210
-
Clinical features and natural history of von Hippel-Lindau disease
-
Maher ER, Yates JRW, Harries R, et al. (1990) Clinical features and natural history of von Hippel-Lindau disease. Q. J. Med. 77: 1151-1163.
-
(1990)
Q. J. Med.
, vol.77
, pp. 1151-1163
-
-
Maher, E.R.1
Yates, J.R.W.2
Harries, R.3
-
3
-
-
0025314788
-
Statistical analysis of the two-stage mutation model in von Hippel-Lindau disease, and in sporadic cerebellar hemangioblastoma and renal cell carcinoma
-
Maher ER, Yates JRW, Ferguson-Smith MA (1990) Statistical analysis of the two-stage mutation model in von Hippel-Lindau disease, and in sporadic cerebellar hemangioblastoma and renal cell carcinoma. J. Med. Genet. 27: 311-314.
-
(1990)
J. Med. Genet.
, vol.27
, pp. 311-314
-
-
Maher, E.R.1
Yates, J.R.W.2
Ferguson-Smith, M.A.3
-
4
-
-
0027240519
-
Identification of the von Hippel-Lindau disease tumor suppressor gene
-
Latif F, Tory K, Gnarra J, et al. (1993) Identification of the von Hippel-Lindau disease tumor suppressor gene. Science 260: 1317-1320.
-
(1993)
Science
, vol.260
, pp. 1317-1320
-
-
Latif, F.1
Tory, K.2
Gnarra, J.3
-
5
-
-
0344330996
-
Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal cell carcinoma
-
Gnarra JR, Duan DR, Weng Y, et al. (1996) Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal cell carcinoma [review]. Biochim. Biophys. Acta 1242: 201-210.
-
(1996)
Biochim. Biophys. Acta
, vol.1242
, pp. 201-210
-
-
Gnarra, J.R.1
Duan, D.R.2
Weng, Y.3
-
6
-
-
0029090338
-
Tumor suppression by the human von Hippel-Lindau gene product
-
Iliopoulos O, Kibel A, Gray S, et al. (1995) Tumor suppression by the human von Hippel-Lindau gene product. Nat. Med. 1: 822-826.
-
(1995)
Nat. Med.
, vol.1
, pp. 822-826
-
-
Iliopoulos, O.1
Kibel, A.2
Gray, S.3
-
7
-
-
0029859624
-
Isolation and characterization of the full-length 3′ untranslated region of the human von Hippel-Lindau tumor suppressor gene
-
Renbaum P, Duh F-M, Latif F, et al. (1996) Isolation and characterization of the full-length 3′ untranslated region of the human von Hippel-Lindau tumor suppressor gene. Hum. Genet. 98: 666-671.
-
(1996)
Hum. Genet.
, vol.98
, pp. 666-671
-
-
Renbaum, P.1
Duh, F.-M.2
Latif, F.3
-
8
-
-
0029028652
-
Characterization of the VHL tumor suppressor gene product: Localization, complex formation, and the effect of natural inactivating mutations
-
Duan DR, Humphrey JS, Chen DYT, et al. (1995) Characterization of the VHL tumor suppressor gene product: Localization, complex formation, and the effect of natural inactivating mutations. Proc. Natl. Acad. Sci. U.S.A. 92: 6495-6499.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 6495-6499
-
-
Duan, D.R.1
Humphrey, J.S.2
Chen, D.Y.T.3
-
9
-
-
0028812223
-
Cloning and characterization of a mouse gene with homology to the human von Hippel-Lindau disease tumor suppressor gene: Implications for the potential organization of the human von Hippel-Lindau disease gene
-
Gao J, Naglich JG, Laidlaw J, et al. (1995) Cloning and characterization of a mouse gene with homology to the human von Hippel-Lindau disease tumor suppressor gene: Implications for the potential organization of the human von Hippel-Lindau disease gene. Cancer Res. 55: 743-747.
-
(1995)
Cancer Res.
, vol.55
, pp. 743-747
-
-
Gao, J.1
Naglich, J.G.2
Laidlaw, J.3
-
10
-
-
0028981766
-
Germ line mutations in the von Hippel-Lindau disease tumor suppressor gene: Correlations with phenotype
-
Chen F, Kishida T, Yao M, et al. (1995) Germ line mutations in the von Hippel-Lindau disease tumor suppressor gene: Correlations with phenotype. Hum. Mutat. 5: 66-75.
-
(1995)
Hum. Mutat.
, vol.5
, pp. 66-75
-
-
Chen, F.1
Kishida, T.2
Yao, M.3
-
11
-
-
0028030581
-
Identification of intragenic mutations in the von Hippel-Lindau disease tumor suppressor gene and correlation with disease phenotype
-
Crossey PA, Richards FM, Foster K, et al. (1994) Identification of intragenic mutations in the von Hippel-Lindau disease tumor suppressor gene and correlation with disease phenotype. Hum. Mol. Gen. 3: 1303-1308.
-
(1994)
Hum. Mol. Gen.
, vol.3
, pp. 1303-1308
-
-
Crossey, P.A.1
Richards, F.M.2
Foster, K.3
-
12
-
-
0027986502
-
Germ-line mutations in the von Hippel-Lindau tumor suppressor gene are similar to somatic von Hippel-Lindau abberations in sporadic renal cell carcinoma
-
Whaley JM, Naglich J, Gelbert L, et al. (1994) Germ-line mutations in the von Hippel-Lindau tumor suppressor gene are similar to somatic von Hippel-Lindau abberations in sporadic renal cell carcinoma. Am. J. Hum. Genet. 55: 1092-1102.
-
(1994)
Am. J. Hum. Genet.
, vol.55
, pp. 1092-1102
-
-
Whaley, J.M.1
Naglich, J.2
Gelbert, L.3
-
13
-
-
16144365122
-
Germline mutations in the von Hippel-Lindau (VHL) gene in families from North America, Europe, and Japan
-
Zbar B, Kishida J, Chen F, et al. (1996) Germline mutations in the von Hippel-Lindau (VHL) gene in families from North America, Europe, and Japan. Hum. Mutat. 8: 348-357.
-
(1996)
Hum. Mutat.
, vol.8
, pp. 348-357
-
-
Zbar, B.1
Kishida, J.2
Chen, F.3
-
14
-
-
0029074707
-
Von Hippel-Lindau disease with pheochromocytoma in the Black Forest region in Germany: Evidence for a founder effect
-
Brauch H, Kishida T, Glavac D, et al. (1995) von Hippel-Lindau disease with pheochromocytoma in the Black Forest region in Germany: Evidence for a founder effect. Hum. Genet. 95: 551-556.
-
(1995)
Hum. Genet.
, vol.95
, pp. 551-556
-
-
Brauch, H.1
Kishida, T.2
Glavac, D.3
-
15
-
-
0025863170
-
Clustering of features of von Hippel-Lindau disease: Evidence of a complex genetic locus
-
Neumann HPH, Wiestler OD (1991) Clustering of features of von Hippel-Lindau disease: Evidence of a complex genetic locus. Lancet 337: 1052-1054.
-
(1991)
Lancet
, vol.337
, pp. 1052-1054
-
-
Neumann, H.P.H.1
Wiestler, O.D.2
-
16
-
-
9344254346
-
Mutations in the VHL tumor suppressor gene and associated lesions in families with von Hippel-Lindau disease from central Europe
-
Glavac D, Neumann HPH, Wittke C, et al. (1996) Mutations in the VHL tumor suppressor gene and associated lesions in families with von Hippel-Lindau disease from central Europe. Hum. Genet. 98: 271-280.
-
(1996)
Hum. Genet.
, vol.98
, pp. 271-280
-
-
Glavac, D.1
Neumann, H.P.H.2
Wittke, C.3
-
17
-
-
0030064811
-
Familial pheochromoccytoma associated with a novel mutation in the von Hippel-Lindau gene
-
Gross D, Avishai N, Meiner V, et al. (1996) Familial pheochromoccytoma associated with a novel mutation in the von Hippel-Lindau gene. J. Clin. Endocrinol. Metab. 81: 147-149.
-
(1996)
J. Clin. Endocrinol. Metab.
, vol.81
, pp. 147-149
-
-
Gross, D.1
Avishai, N.2
Meiner, V.3
-
18
-
-
0029864421
-
Isolated familial pheochromocytoma as a variant of von Hippel-Lindau disease
-
Ritter M, Frilling A, Crossey P, et al. (1996) Isolated familial pheochromocytoma as a variant of von Hippel-Lindau disease. J. Clin. Endocrinol. Metab. 81: 1035-1037.
-
(1996)
J. Clin. Endocrinol. Metab.
, vol.81
, pp. 1035-1037
-
-
Ritter, M.1
Frilling, A.2
Crossey, P.3
-
19
-
-
0027508442
-
Pheochromocytomas, multiple endocrine neoplasia type 2, and von Hippel-Lindau disease
-
Neumann HPH, Berger DP, Sigmund G, et al. (1993) Pheochromocytomas, multiple endocrine neoplasia type 2, and von Hippel-Lindau disease. N. Engl. J. Med. 329: 1531-1538.
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 1531-1538
-
-
Neumann, H.P.H.1
Berger, D.P.2
Sigmund, G.3
-
20
-
-
0027954044
-
Mutations of the VHL tumour suppressor gene in renal carcinoma
-
Gnarra JR, Tory K, Weng Y, et al. (1994) Mutations of the VHL tumour suppressor gene in renal carcinoma. Nat. Genet. 7: 85-90.
-
(1994)
Nat. Genet.
, vol.7
, pp. 85-90
-
-
Gnarra, J.R.1
Tory, K.2
Weng, Y.3
-
21
-
-
0028235907
-
Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas
-
Shuin T, Kondo K, Torigoe S, et al. (1994) Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas. Cancer Res. 54: 2852-2855.
-
(1994)
Cancer Res.
, vol.54
, pp. 2852-2855
-
-
Shuin, T.1
Kondo, K.2
Torigoe, S.3
-
22
-
-
0028072991
-
Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma
-
Herman JG, Latif F, Weng Y, et al. (1994) Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. Proc. Natl. Acad. Sci. U.S.A. 91: 9700-9704.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 9700-9704
-
-
Herman, J.G.1
Latif, F.2
Weng, Y.3
-
23
-
-
0028587585
-
Somatic mutations of the von Hippel-Lindau disease tumor suppressor gene in non-familial clear cell renal carcinoma
-
Foster K, Prowse A, van den Berg A, et al. (1994) Somatic mutations of the von Hippel-Lindau disease tumor suppressor gene in non-familial clear cell renal carcinoma. Hum. Mol. Genet. 3: 2169-2173.
-
(1994)
Hum. Mol. Genet.
, vol.3
, pp. 2169-2173
-
-
Foster, K.1
Prowse, A.2
Van Den Berg, A.3
-
24
-
-
0027938458
-
Somatic mutations of the von Hippel-Lindau Tumor suppressor gene in sporadic central nervous systems hemangioblastomas
-
Kanno H, Kondo K, Ito S, et al. (1994) Somatic mutations of the von Hippel-Lindau Tumor suppressor gene in sporadic central nervous systems hemangioblastomas. Cancer Res. 54: 4845-4847.
-
(1994)
Cancer Res.
, vol.54
, pp. 4845-4847
-
-
Kanno, H.1
Kondo, K.2
Ito, S.3
-
25
-
-
0029847090
-
Allelic deletions of the VHL gene detected in multiple microscopic clear cell renal lesions in von Hippel-Lindau disease patients
-
Lubensky IA, Gnarra JR, Bertheau P, et al. (1996) Allelic deletions of the VHL gene detected in multiple microscopic clear cell renal lesions in von Hippel-Lindau disease patients. Am. J. Pathol. 149: 2089-2094.
-
(1996)
Am. J. Pathol.
, vol.149
, pp. 2089-2094
-
-
Lubensky, I.A.1
Gnarra, J.R.2
Bertheau, P.3
-
26
-
-
0028954688
-
A microscopic dissection technique for archival DNA analysis of specific cell populations in lesions <1 mm in size
-
Zhuang Z, Bertheau P, Emmert-Buck M, et al. (1995) A microscopic dissection technique for archival DNA analysis of specific cell populations in lesions <1 mm in size. Am. J. Pathol. 146: 620-625.
-
(1995)
Am. J. Pathol.
, vol.146
, pp. 620-625
-
-
Zhuang, Z.1
Bertheau, P.2
Emmert-Buck, M.3
-
27
-
-
10144242640
-
Extensive mutation scanning of RET in sporadic medullary thyroid carcinoma and of RET and VHL in sporadic pheochromocytoma reveals involvement of these genes in only a minority of cases
-
Hofstra RMW, Stelwagen T, Stulp RP, et al. (1996) Extensive mutation scanning of RET in sporadic medullary thyroid carcinoma and of RET and VHL in sporadic pheochromocytoma reveals involvement of these genes in only a minority of cases. J. Clin. Endocrinol. Metab. 81: 2881-2884.
-
(1996)
J. Clin. Endocrinol. Metab.
, vol.81
, pp. 2881-2884
-
-
Hofstra, R.M.W.1
Stelwagen, T.2
Stulp, R.P.3
-
28
-
-
10544244175
-
Von Hippel-Lindau tumor suppressor gene. Localization of expression by in situ hybridization
-
Nagashima Y, Miyagi Y, Udagawa K, et al. (1996) von Hippel-Lindau tumor suppressor gene. Localization of expression by in situ hybridization. J. Pathol. 180: 271-274.
-
(1996)
J. Pathol.
, vol.180
, pp. 271-274
-
-
Nagashima, Y.1
Miyagi, Y.2
Udagawa, K.3
-
29
-
-
0029772338
-
Expression pattern of the von Hippel-Lindau protein in human tissues
-
Los M, Jansen GH, Kaelin WG, et al. (1996) Expression pattern of the von Hippel-Lindau protein in human tissues. Lab. Invest. 75: 231-238.
-
(1996)
Lab. Invest.
, vol.75
, pp. 231-238
-
-
Los, M.1
Jansen, G.H.2
Kaelin, W.G.3
-
30
-
-
0030948396
-
Immunostaining of the von Hippel-Lindau gene product (pVHL) in normal and neoplastic human tissues
-
Corless CL, Kibel A, Iliopoulos O, et al. (1997) Immunostaining of the von Hippel-Lindau gene product (pVHL) in normal and neoplastic human tissues. Hum. Pathol. 28: 459-464.
-
(1997)
Hum. Pathol.
, vol.28
, pp. 459-464
-
-
Corless, C.L.1
Kibel, A.2
Iliopoulos, O.3
-
31
-
-
0029946004
-
Nuclear/cytoplasmic localization of the von Hippel-Lindau tumor suppressor gene product is determined by cell density
-
Lee S, Chen DYT, Humphrey JS, et al. (1996) Nuclear/cytoplasmic localization of the von Hippel-Lindau tumor suppressor gene product is determined by cell density. Proc. Natl. Acad. Sci. U.S.A. 93: 1770-1775.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 1770-1775
-
-
Lee, S.1
Chen, D.Y.T.2
Humphrey, J.S.3
-
32
-
-
0029785838
-
Post-transcriptional regulation of vascular endothelial growth factor mRNA by the VHL tumor suppressor gene product
-
Gnarra JR, Zhou S, Merrill MJ, et al. (1996) Post-transcriptional regulation of vascular endothelial growth factor mRNA by the VHL tumor suppressor gene product. Proc. Natl. Acad. Sci. U.S.A. 93: 10589-10594.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 10589-10594
-
-
Gnarra, J.R.1
Zhou, S.2
Merrill, M.J.3
-
33
-
-
0028805059
-
Suppression of growth of renal carcinoma cells by the von Hippel-Lindau tumor suppressor gene
-
Chen F, Kishida T, Dun F-M, et al. (1995) Suppression of growth of renal carcinoma cells by the von Hippel-Lindau tumor suppressor gene. Cancer Res. 55: 4804-4807.
-
(1995)
Cancer Res.
, vol.55
, pp. 4804-4807
-
-
Chen, F.1
Kishida, T.2
Dun, F.-M.3
-
34
-
-
0029147430
-
Binding of the von Hippel-Lindau tumor suppressor protein to elongin B and C
-
Kibel A, Iliopoulos O, DeCaprio JD, et al. (1995) Binding of the von Hippel-Lindau tumor suppressor protein to elongin B and C. Science 269: 1444-1446.
-
(1995)
Science
, vol.269
, pp. 1444-1446
-
-
Kibel, A.1
Iliopoulos, O.2
DeCaprio, J.D.3
-
35
-
-
0029126892
-
Inhibition of transcription elongation by the VHL tumor suppressor protein
-
Duan DR, Pause A, Burgress W, et al. (1995) Inhibition of transcription elongation by the VHL tumor suppressor protein. Science 269: 1402-1406.
-
(1995)
Science
, vol.269
, pp. 1402-1406
-
-
Duan, D.R.1
Pause, A.2
Burgress, W.3
-
36
-
-
0029941650
-
Identification of a novel protein (VBP-1) binding to the von Hippel-Lindau (VHL) tumor suppressor gene product
-
Tsuchiya H, Iseda T, Hino O (1996) Identification of a novel protein (VBP-1) binding to the von Hippel-Lindau (VHL) tumor suppressor gene product. Cancer Res. 56: 2881-2885.
-
(1996)
Cancer Res.
, vol.56
, pp. 2881-2885
-
-
Tsuchiya, H.1
Iseda, T.2
Hino, O.3
-
37
-
-
0028826589
-
Cellular proteins that bind the von Hippel-Lindau disease gene product: Mapping of binding domains and the effect of missense mutations
-
Kishida T, Stackhouse TM, Chen F, et al. (1995) Cellular proteins that bind the von Hippel-Lindau disease gene product: Mapping of binding domains and the effect of missense mutations. Cancer Res. 55: 4544-4548.
-
(1995)
Cancer Res.
, vol.55
, pp. 4544-4548
-
-
Kishida, T.1
Stackhouse, T.M.2
Chen, F.3
-
38
-
-
0029084914
-
Elongin (SIII): A multisubunit regulator of elongation by RNA polymerase II
-
Aso T, Lane WS, Conaway JW, et al. (1995) Elongin (SIII): A multisubunit regulator of elongation by RNA polymerase II. Science 269: 1439-1443.
-
(1995)
Science
, vol.269
, pp. 1439-1443
-
-
Aso, T.1
Lane, W.S.2
Conaway, J.W.3
-
39
-
-
0029785321
-
Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein
-
Iliopoulos O, Jiang C, Levy AP, et al. (1996) Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein. Proc. Natl. Acad. Sci. U.S.A. 93: 10595-10599.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 10595-10599
-
-
Iliopoulos, O.1
Jiang, C.2
Levy, A.P.3
-
40
-
-
0029920054
-
Reversion of deregulated expression of vascular endothelial growth factor in human renal carcinoma cells by von Hippel-Lindau tumor suppressor protein
-
Siemeister G, Weindel K, Mohrs K, et al. (1996) Reversion of deregulated expression of vascular endothelial growth factor in human renal carcinoma cells by von Hippel-Lindau tumor suppressor protein. Cancer Res. 56: 2299-2301.
-
(1996)
Cancer Res.
, vol.56
, pp. 2299-2301
-
-
Siemeister, G.1
Weindel, K.2
Mohrs, K.3
-
41
-
-
0029166443
-
Regulation of the expression of the VEGF/VPS and its receptors: Role in tumor angiogenesis
-
Kolch W, Martiny-Baron G, Kieser A, et al. (1995) Regulation of the expression of the VEGF/VPS and its receptors: Role in tumor angiogenesis. Breast Cancer Res. Treat. 36: 139-155.
-
(1995)
Breast Cancer Res. Treat.
, vol.36
, pp. 139-155
-
-
Kolch, W.1
Martiny-Baron, G.2
Kieser, A.3
-
42
-
-
0031027287
-
Regulation of vascular endothelial growth factor by hypoxia and its modulation by the von Hippel-Lindau tumor suppressor gene
-
Levy AP, Levy NS, Iliopoulos O, et al. (1997) Regulation of vascular endothelial growth factor by hypoxia and its modulation by the von Hippel-Lindau tumor suppressor gene. Kidney Int. 51: 575-578.
-
(1997)
Kidney Int.
, vol.51
, pp. 575-578
-
-
Levy, A.P.1
Levy, N.S.2
Iliopoulos, O.3
-
43
-
-
0029795584
-
Hypoxia-inducible protein binding to vascular endothelial growth factor mRNA and its modulation by the von Hippel-Lindau protein
-
Levy AP, Levy NS, Goldberg MA (1996) Hypoxia-inducible protein binding to vascular endothelial growth factor mRNA and its modulation by the von Hippel-Lindau protein. J. Biol. Chem. 271: 25492-25497.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 25492-25497
-
-
Levy, A.P.1
Levy, N.S.2
Goldberg, M.A.3
|