The effect of cholesterol in small amounts on lipid-bilayer softness in the region of the main phase transition

European Biophysics Journal

Volumn 25, Issue 4, 1997, Pages 293-304

  Lemmich, Jesper ^a   Mortensen, Kell ^a   Ipsen, John Hjort ^a   Hønger, Thomas ^a   Bauer, Rogert ^b   Mouritsen, Ole G ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Bilayer rigidity; Cholesterol; DMPC; Fluctuations; Small angle neutron scattering; Unbinding transition

Indexed keywords

CHOLESTEROL; DIMYRISTOYLPHOSPHATIDYLCHOLINE;

AQUEOUS SOLUTION; ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; GEL; GEOMETRY; HYDROPHOBICITY; LIPID BILAYER; LIQUID; NEUTRON SCATTERING; PHASE TRANSITION; TEMPERATURE; YOUNG MODULUS;

EID: 0030849774     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002490050041     Document Type: Article

References (47)

1. Bloom M, Evans E, Mouritsen OG (1991) Physical properties of the fluid-bilayer component of cell membranes: a perspective. Q Rev Biophys 24:293-397
2. Bloom M, Mouritsen OG (1995) The evolution of membranes.In: Lipowsky R, Sackmann E (eds) Handbook of Biological Physics, Vol. 1. Elsevier Science BV, pp 65-95
3. Blume M, Hillmann M (1986) Dimyristoylphosphatidicacid/cholesterol bilayers. Thermodynamic properties and kinetics of phase transitions as studied by pressure jump relaxation technique. Eur Biophys J 13:343-353
4. Bretscher MS, Munro S (1993) Cholesterol and the Golgi Apparatus. Science 261:1280-1281
5. Caillé A (1972) Remarques sur la diffusion des rayons X dans les smectiques A. CR Acad Sci Paris, Ser B 274:891-893
6. Corvera E, Mouritsen OG, Singer MA, Zuckermann MJ (1992) The permeability and the effect of acyl chain length for phospholipid bilayers containing cholesterol: theory and experiment. Biochim Biophys Acta 1107:261-270
7. Cruzeiro-Hansson L, Ipsen JH, Mouritsen OG (1989) Intrinsic molecules in lipid membranes change the lipid-domain interfacial area: cholesteral at domain boundaries. Biochim Biophys Acta 979:166-176
8. de Gier J, Noordam PC, van Echteld CAJ, Mandersloot JG, Bijleveld C, Verkleij J, Cullis PR, de Kruiff B (1979) The barrier function of membrane lipids. In: Lassen UV, Ussing HH, Wieth JO (eds) Membrane transport in erythrocytes. Alfred Benzon Symp. 14. Munksgaard, Copenhagen, pp 75-85
9. 2H-NMR. Biochim Biophys Acta 737: 117-171
10. Fernandez-Puente L, Bivas I, Mitov MD, Méléard P (1994) Temperature and chain length effects on bending elasticity of phosphatidylcholine bilayers. Europhys Lett 28:181-186
11. Finegold L (ed) (1993) Cholesterol and membrane models. CRC Press, Inc, Boca Raton, Fl pp 273
12. Genz A, Holzwarth JF, Tsong TS (1986) The influence of cholesterol on the main phase transition of unilamellar dipalmitoylphosphatidylcholine vesicles. Biophys J 50:1043-1051
13. Helfrich W (1973) Elastic properties of lipid bilayers: theory and possible experiments. Z Naturforsch 28c:693-703
14. Helfrich W (1978) Steric interactions of fluid membranes in multilayer systems. Z Naturforsch 33a:305-315
15. Hosemann R, Bagchi SN (1962) Direct analysis of diffraction by matter. North-Holland, Amsterdam, pp 408-423
16. Hønger T, Mortensen K, Ipsen JH, Lemmich J, Bauer R, Mouritsen OG (1994) Anomalous swelling of multilamellar lipid bilayers in the transition region by renormalization of curvature elasticity. Phys Rev Lett 72:3911-3914
17. Hui SW, He N-B (1983) Molecular organization in cholesterol-lecithin bilayers by X-ray and electron diffraction measurements. Biochemistry 22:1159-1164
18. Ipsen JH, Karlström G, Mouritsen OG, Wennerström H, Zuckermann MJ (1987) Phase equilibria in the phosphatidylcholine-cholesterol system. Biochim Biophys Acta 905:162-172
19. Ipsen JH, Jørgensen K, Mouritsen OG (1990a) Density fluctuations in saturated phospholipid bilayers increase as the acyl-chain length decreases. Biophys J 58:1099-1107
20. Ipsen JH, Mouritsen OG, Bloom M (1990b) Relationship between lipid membrane area, hydrophobic thickness, and acyl-chain orientational order. The effects of cholesterol. Biophys J 57: 405-412
21. Jamieson GA, Robinson DM (1977) Mammalian cell membranes, vol 2. Butterworth, London
22. Leibler S, Lipowsky R (1987) Complete unbinding and quasi-long-range order in lamellar phases. Phys Rev B 35:7004-7009
23. Lemmich J, Mortensen K, Ipsen JH, Hønger T, Bauer R, Mouritsen OG (1995) Pseudocritical behavior and unbinding of phospholipid bilayers. Phys Rev Lett 75:3958-3961
24. Lemmich J (1996) Lipid bilayers studied by small-angle neutron scattering. Ph D Thesis, Technical University of Denmark, Lyngby, Denmark, pp 136
25. Lemmich J, Mortensen K, Ipsen JH, Hønger T, Bauer R, Mouritsen OG (1996a) Small-angle neutron scattering from multilamellar lipid bilayers: theory, model and experiment. Phys Rev E 53:5169-5180
26. Lemmich J, Hønger T, Mortensen K, Ipsen JH, Bauer R, Mouritsen OG (1996b) Solutes in small amounts provide for lipid-bilayer softness: cholesterol, short-chain lipids, and bola lipids. Eur Biophys J 25:61-65
27. Lipowsky R, Leibler S (1986) Unbinding transitions of interacting membranes. Phys Rev Lett 56:2541-2542
28. Lipowsky R (1988) Lines of renormalization group fixed points for fluid and crystalline membranes. Europhys Lett 7:255-261
29. Matuoka S, Kato S, Akiyama M, Amemiya Y, Hatta I (1990) Temperature dependence of the ripple structure in dimyristoylphosphatidylcholine studied by synchrotron X-ray small-angle diffraction. Biochim Biophys Acta 1028:103-109
30. Matuoka S, Kato S, Hatta I (1994) Temperature change of the ripple structure in fully hydrated dimyristoylphosphatidylcholine/cholesterol multilayers. Biophys J 67:728-736
31. Michels B, Fazel N, Cerf R (1989) Enhanced fluctuations in small phospholipid bilayer vesicles containing cholesterol. Eur Biophys J 17:187-190
32. Mortensen K, Pfeiffer W, Sackmann E, Knoll W (1988) Structural properties of a phosphatidylcholine-cholesterol system as studies by small-angle neutron scattering: ripple structure and phase diagram. Biochim Biophys Acta 945:221-245
33. Mouritsen OG, Jørgensen K (1994) Dynamical order and disorder in lipid bilayers. Chem Phys Lipids 73:3-25
34. Munro S (1995) A comparison of the membrane domains of Golgi and plasma membrane proteins. Biochem Soc Trans 23:527-530
35. Nallet F, Laversanne R, Roux D (1993) Modelling X-ray or neutron scattering spectra of lyotropic lamellar phases: interplay between form and structure factors. J Phys II France 3:487-502
36. Needham D, Evans E (1988) Structure and mechanical properties of giant lipid (DMPC) vesicles from 20 °C below to 10 °C above the liquid crystal-crystalline transition at 24 °C. Biochemistry 27:8261-8269
37. Needham D, McIntosh TJ, Evans E (1988) Thermomechanical and transition properties of dimyristoylphosphatidylcholine/cholesterol bilayers. Biochemistry 27:4668-4673
38. Pelham HRB, Munro S (1993) Sorting of membrane proteins in the secretory pathway. Cell 75:603-605
39. Schindler H, Seelig J (1975) Deuterium order parameters in relation to thermodynamic properties of a phospholipid bilayer. A statistical mechanical interpretation. Biochemistry 14:2283-2287
40. Seelig A, Seelig J (1974) The dynamic structure of fatty acyl chains in a phospholipid bilayer measured by deuterium magnetic resonance. Biochemistry 13:4839-4845
41. Spink CH, Manley S, Breed M (1996) Thermodynamics of transfer of cholesterol from gel to fluid phases of phospholipid bilayers. Biochim Biophys Acta 1279:190-196
42. Vist MR (1984) Partial phase behavior of perdeuterated dipalmitoylphosphatidylcholine-cholesterol model membranes. M Sc Thesis, University of Guelph, Ontario, Canada, pp 103
43. 2H NMR and differential scanning calorimetry. Biochemistry 29:451-464
44. Yeagle PL (1988) Cholesterol and the cell membrane. In: Yeagle PL (ed) Biology of cholesterol. CRC Press, Inc, Boca Raton, FL, pp 121-145
45. Zhang R, Suter RM, Nagle JF (1994) Theory of the structure factor of lipid bilayers. Phys Rev E 50:5047-5060
46. Zhang R, Tristram-Nagle S, Sun W, Headrick RL, Irving TC, Suter RM, Nagle JF (1996) Small-angle X-ray scattering from lipid bilayers is well described by modified Caillé theory but not by paracrystalline theory. Biophys J 70:349-357
47. Zuckermann MJ, Ipsen JH, Mouritsen OG (1993) Theoretical studies of the phase behavior of lipid bilayers containing cholesterol. In: Finegold L (ed) Cholesterol and membrane models. CRC Press, Inc, Boca Raton, FL, pp 223-257