The treatment of febrile neutropenia: From the dark ages to the present

Supportive Care in Cancer

Volumn 5, Issue 5, 1997, Pages 351-357

  Bodey, Gerald P ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Antibiotics; Infection; Neutropenia; Pathogens

Indexed keywords

AMIKACIN; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; CARBENICILLIN; CEFALOTIN; CEFTAZIDIME; COLISTIN; GENTAMICIN; METICILLIN; MEZLOCILLIN; PIPERACILLIN; POLYMYXIN B; SISOMICIN; TICARCILLIN; TOBRAMYCIN;

ANTIBIOTIC THERAPY; CANCER PATIENT; CLINICAL TRIAL; DRUG RESPONSE; ESCHERICHIA COLI; FEVER; GRAM NEGATIVE INFECTION; HUMAN; INFECTION; KLEBSIELLA; NEUTROPENIA; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; REVIEW; SEPTICEMIA; STAPHYLOCOCCUS INFECTION; SURVIVAL;

ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; CLINICAL TRIALS; FEVER; HISTORY, 20TH CENTURY; HUMANS; NEUTROPENIA; PROGNOSIS;

EID: 0030848701     PISSN: 09414355     EISSN: None     Source Type: Journal    
DOI: 10.1007/s005200050091     Document Type: Review

References (33)

1. Anaissie EJ, Fainstein V, Bodey GP, et al (1988) Randomized trial of beta-lactam regimens in febrile neutropenic cancer patients. Am J Med 84:581-589
2. Bochud PY, Calandra T, Francioli P (1994) Bacteremia due to viridans streptococci in neutropenic patients: a review. Am J Med 97:256-264
3. Bodey GP (1984) Antibiotics in patients with neutropenia. Arch Intern Med 144:1845-1851
4. Bodey GP, Nies BA, Mohberg NR, et al (1964) Use of gamma globulin in infection in acute leukemia patients. JAMA 190:1099-1102
5. Bodey GP, Nies BA, Mohberg NR, et al (1965) The effect of adrenal corticosteroid therapy on infections in acute leukemia. Am J Med Sci 250:162-167
6. Bodey GP, Buckley M, Sathe YS, et al (1966) Quantitative relationships between circulating leukocytes and infection in patients with acute leukemia. Ann Intern Med 64:328-340
7. Bodey GP, Whitecar JP Jr, Middleman E, et al (1971) Carbenicillin therapy of pseudomonas infections. JAMA 218:62-66
8. Bodey GP, Middleman E, Umsawasdi T, et al (1972) Infections in cancer patients - results with gentamicin sulfate therapy. Cancer 29:1697-1701
9. Curtin JA, Marshall BD Jr (1962) Use of antibiotics in cancer and leukemia. J Chronic Dis 15:713-718
10. DePauw BE, Deresinski SC, Feld R, et al (1994) Ceftazidime compared with piperacillin and tobramycin for the empiric treatment of fever in neutropenic patients with cancer. A multicenter randomized trial. Ann Intern Med 120:834-844
11. EORTC International Antimicrobial Therapy Cooperative Group (1987) Ceftazidime combined with a short or long course of amikacin for empirical therapy of gram-negative bacteremia in cancer patients with granulocytopema. N Engl J Med 317:1692-1698
12. EORTC International Antimicrobial Therapy Cooperative Group (1993) Efficacy and toxicity of single daily doses of amikacin and ceftriaxone versus multiple daily doses of amikacin and ceftazidime for infection in patients with cancer and granulocytopenia. Ann Intern Med 119:584-593
13. EORTC International Antimicrobial Therapy Cooperative Group and the National Cancer Institute of Canada - Clinical Trials Group (1991) Vancomyin added to empirical combination antibiotic therapy for fever in granulocytopenic cancer patients. J Infect Dis 163:951-958
14. EORTC International Antimicrobial Therapy Project Group (1978) Three antibiotic regimens in the treatment of infection in febrile granulocytopenic patients with cancer. J Infect Dis 137:14-29
15. Fainstein V, Bodey GP, Elting L, et al (1983) A randomized study of ceftazidime compared to ceftazidime and tobramycin for the treatment of infections in cancer patients. J Antimicrob Chemother 12 [Suppl A]: 101-110
16. Fainstein V, Bodey GP, Bolivar R, et al (1984) Moxalactam plus ticarcillin or tobramycin in the treatment of febrile episodes in granulocytopenic cancer patients. Arch Intern Med 144:1766-1770
17. Hersh EM, Bodey GP, Nies BA, et al (1965) Causes of death in acute leukemia. A ten year study of 414 patients from 1954-1963. JAMA 193:105-109
18. Jones PG, Rolston KVI, Fainstein V, et al (1986) Aztreonam therapy in neutropenic cancer patients. Am J Med 81 :243-248
19. Klastersky J, Cappel R, Daneau, D (1972) Clinical significance of in vitro synergism between antibiotics in gram-negative infections. Antimicrob Agents Chemother 2:470-475
20. Klastersky J, Glauser MP, Schimpff SC, et al (1986) Prospective randomized comparison of three antibiotic regimens for empirical therapy of suspected bacteremic infection in febrile granulocytopenic patients. Antimicrob Agents Chemother 29:263-270
21. Klastersky J, Zinner SH, Calandra T, et al (1988) Empiric antimicrobial therapy for febrile granulocytopenic cancer patients: Lessons from four EORTC trials. Eur J Cancer Clin Oncol 24:S35-S45
22. Middleman EA, Watanabe A, Kaizer H, et al (1972) Antibiotic combinations for infections in neutropenic patients. Evaluation of carbenicillin plus either cephalothin or kanamycin. Cancer 30:573-579
23. Montecalvo MA, Horowitz H, Gedris C, et al (1994) Outbreak of vancomycyin-, ampicillin-, and aminoglycoside-resistant Enterococcus faecium bacteremia in an adult oncology unit. Antimicrob Agents Chemother 38:1363-1367
24. Piccart M, Klastersky J, Meunier F, et al (1984) Single-drug versus combination empirical therapy for gram-negative bacillary infections in febrile cancer patients with and without granulocytopenia. Antimicrob Agents Chemother 26:870-875
25. Pizzo PA, Hathorn JW, Hiemenz J, et al (1986) A randomized trial comparing ceftazidime alone with combination antibiotic therapy in cancer patients with fever and neutropenia. N Engl J Med 315:552-558
26. Rolston VKI, Berkey P, Bodey GP, et al (1992) A comparison of imipenem to ceftazidime with or without amikacin as empiric therapy in febrile neutropenic patients. Arch Intern Med 152:283-291
27. Rubenstein EB, Rolston K, Benjamin RS, et al (1993) Out patient treatment of febrile episodes in low risk neutropenic cancer patients. Cancer 71:3640-3646
28. Schimpff S, Satterlee W, Young VM, et al (1971) Empiric therapy with carbenicillin and gentamicin for febrile patients with cancer and granulocytopenia. N Engl J Med 284:1061-1065
29. Silver RT (1963) Infection, fever and host resistance in neoplastic disease. J Chronic Dis 16:677-681
30. Talcott JA, Finberg R, Mayer RJ, et al. (1988) The medical course of cancer patients with fever and neutropenia. Clinical identification of a low-risk subgroup at presentation. Arch Intern Med 148:2561-2568
31. Valdivieso M, Horikoshi N, Rodriguez V, et al (1974) Therapeutic trials with tobramycin. Am J Med Sci 268:149-156
32. Whitecar JP Jr, Bodey GP, Luna M (1970) Pseudomonas bacteremia in cancer patients. Am J Med Sci 260:216-223
33. Winston DJ, Barnes RC, Ho WG, et al (1984) Moxalactam plus piperacillin versus moxalactam plus amikacin in febrile granulocytopenic patients. Am J Med 77:442-450