Capsaicin's effect on rat nasal mucosa substance P release: Experimental basis for vasomotor rhinitis treatment

American Journal of Rhinology

Volumn 11, Issue 4, 1997, Pages 313-316

  Kuhn, Frederick A ^a   Gonzalez, Sergio ^b   Rodriguez, Magdalena ^c   Siller, Carlos Guilty ^c   Zachariou, Venetia ^d   Goldstein, Barry D ^e  

^a Georgia Ear Institute   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^c Yale University ^*

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPHYLLINE; CAPSAICIN; SUBSTANCE P; TERBUTALINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; INTRANASAL DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NOCICEPTIVE STIMULATION; NONHUMAN; NOSE MUCOSA; NOSE SECRETION; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; VASOMOTOR RHINITIS;

EID: 0030848628     PISSN: 10506586     EISSN: None     Source Type: Journal    
DOI: 10.2500/105065897781446649     Document Type: Article

References (6)

1. Hokfelt T, Kellerth JP, Nilsson G, Pernow B. Substance P: Localization in the central nervous system and in some primary sensory neurons. Science 190:889-890, 1975.
2. Uddman R, Malm L, Sundler F. Substance P containing nerve fibers in the nasal mucosa. Arch Oto Rhino Laryngol 238:9-16, 1983.
3. Saria A, Wolf G. Beneficial effect of topically applied capsaicin in the treatment of hyperreactive neuropathy. Regul Pept 22:167, 1988.
4. Marabini S, Ciabatti G, Polli G, et al. Effect of topical nasal treatment with capsaicin in vasomotor rhinitis. Regul Pept 22:121, 1988.
5. Marsh SJ, Stansfeld CE, Brown DA, et al. The mechanism of action of capsaicin on sensory C-type neurons and their axons in vitro. Neuroscience 23:275-289, 1987.
6. Wood JN, Winter J, James IF, et al. Capsaicin induced ion fluxes in dorsal root ganglion cells in culture. J Neurosci 8:3207-3220, 1988.