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Volumn 26, Issue 4, 1997, Pages 1045-1053

Isolation and molecular characterization of hepatitis B virus X-protein from a baculovirus expression system

Author keywords

[No Author keywords available]

Indexed keywords

REGULATOR PROTEIN; VIRUS PROTEIN;

EID: 0030848423     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510260437     Document Type: Article
Times cited : (37)

References (42)
  • 1
    • 0017796073 scopus 로고
    • Hepatocellular carcinoma and the hepatitis B virus: Evidence for a causal association
    • Szmuness W. Hepatocellular carcinoma and the hepatitis B virus: evidence for a causal association. Prog Med Virol 1978;24:40-69.
    • (1978) Prog Med Virol , vol.24 , pp. 40-69
    • Szmuness, W.1
  • 2
    • 0019451351 scopus 로고
    • Hepatocellular carcinoma and hepatitis B virus. A prospective study of 22,707 men in Taiwan
    • Beasley RP, Lin CC, Hwang LY, Chien CS. Hepatocellular carcinoma and hepatitis B virus. A prospective study of 22,707 men in Taiwan. Lancet 1981;2:1129-1133.
    • (1981) Lancet , vol.2 , pp. 1129-1133
    • Beasley, R.P.1    Lin, C.C.2    Hwang, L.Y.3    Chien, C.S.4
  • 3
    • 0002590132 scopus 로고
    • Hepatitis B virus
    • Fields BN, Knipe DM, eds. New York: Raven
    • Hollinger FB: Hepatitis B virus. In: Fields BN, Knipe DM, eds. Virology. New York: Raven, 1990:2171-2238.
    • (1990) Virology , pp. 2171-2238
    • Hollinger, F.B.1
  • 4
    • 0025995441 scopus 로고
    • Hepadnaviruses and hepatocellular carcinoma
    • Sherker AH, Marion PL. Hepadnaviruses and hepatocellular carcinoma. Ann Rev Microbiol 1991;45:475-508.
    • (1991) Ann Rev Microbiol , vol.45 , pp. 475-508
    • Sherker, A.H.1    Marion, P.L.2
  • 5
    • 0023080494 scopus 로고
    • The molecular biology of the Hepatitis B viruses
    • Ganem D, Varmus HE. The molecular biology of the Hepatitis B viruses. Ann Rev Biochem 1987;56:651-693.
    • (1987) Ann Rev Biochem , vol.56 , pp. 651-693
    • Ganem, D.1    Varmus, H.E.2
  • 6
    • 0023627343 scopus 로고
    • Transcriptional trans-activating function of hepatitis B virus
    • Twu JS, Schloemer RH. Transcriptional trans-activating function of hepatitis B virus. J Virol 1987;61:3448-3453.
    • (1987) J Virol , vol.61 , pp. 3448-3453
    • Twu, J.S.1    Schloemer, R.H.2
  • 7
    • 0024240296 scopus 로고
    • A transactivating function encoded in the hepatitis B virus X gene is conserved in the integrated state
    • Wollersheim M, Debelka U, Hofschneider PH. A transactivating function encoded in the hepatitis B virus X gene is conserved in the integrated state. Oncogene 1988;3:545-552.
    • (1988) Oncogene , vol.3 , pp. 545-552
    • Wollersheim, M.1    Debelka, U.2    Hofschneider, P.H.3
  • 8
    • 0023711995 scopus 로고
    • The HBV X-ORF encodes a trans-activator: A potential factor in viral hepatocarcinogenesis
    • Zahm P, Hofschneider PH, Koshy R. The HBV X-ORF encodes a trans-activator: a potential factor in viral hepatocarcinogenesis. Oncogene 1988;3:169-177.
    • (1988) Oncogene , vol.3 , pp. 169-177
    • Zahm, P.1    Hofschneider, P.H.2    Koshy, R.3
  • 9
    • 0025231364 scopus 로고
    • A trans-activator function is generated by integration of hepatitis B virus preS/S sequences in human hepatocellular carcinoma DNA
    • Caselmann WH, Meyer M, Kekulé AS, Lauer U, Hofschneider PH, Koshy R. A trans-activator function is generated by integration of hepatitis B virus preS/S sequences in human hepatocellular carcinoma DNA. Proc Natl Acad Sci U S A 1990;87:2970-2974.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 2970-2974
    • Caselmann, W.H.1    Meyer, M.2    Kekulé, A.S.3    Lauer, U.4    Hofschneider, P.H.5    Koshy, R.6
  • 10
    • 0025098651 scopus 로고
    • The preS2/S region of integrated hepatitis B virus DNA encodes a transcriptional transactivator
    • Kekulé AS, Lauer U, Meyer M, Caselmann WH, Hofschneider PH, Koshy R. The preS2/S region of integrated hepatitis B virus DNA encodes a transcriptional transactivator. Nature 1990;343:457-461.
    • (1990) Nature , vol.343 , pp. 457-461
    • Kekulé, A.S.1    Lauer, U.2    Meyer, M.3    Caselmann, W.H.4    Hofschneider, P.H.5    Koshy, R.6
  • 11
    • 0030267994 scopus 로고    scopus 로고
    • The role of hepatitis B virus (HBV) in the development of hepatocellular carcinoma
    • Hildt E, Hofschneider PH, Urban S. The role of hepatitis B virus (HBV) in the development of hepatocellular carcinoma. Semin Virol 1996;7: 333-347.
    • (1996) Semin Virol , vol.7 , pp. 333-347
    • Hildt, E.1    Hofschneider, P.H.2    Urban, S.3
  • 12
    • 0030041821 scopus 로고    scopus 로고
    • Hepadnaviral X protein: Review of recent progress
    • Yen TSB. Hepadnaviral X protein: review of recent progress. J Biomed Sci 1996;3:20-30.
    • (1996) J Biomed Sci , vol.3 , pp. 20-30
    • Yen, T.S.B.1
  • 13
    • 0027305913 scopus 로고
    • Transactivation by hepatitis B virus X protein is promiscuous and dependent on mitogen-activated cellular serin/threonin kinases
    • Cross JC, Wen P, Rutter WJ. Transactivation by hepatitis B virus X protein is promiscuous and dependent on mitogen-activated cellular serin/threonin kinases. Proc Natl Acad Sci U S A 1993;90:8078-8082.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 8078-8082
    • Cross, J.C.1    Wen, P.2    Rutter, W.J.3
  • 14
    • 12644292253 scopus 로고
    • Activation of the transcription factor C-Jun/Apl by the hepatitis-B virus transactivator Px occurs through a Ras-dependent and Raf-dependent signaling pathway
    • Natoli G, Chirillo P, Avantaggiati ML, Costanzo A, Ianni A, Demarzio E, Puri, P. et al. Activation of the transcription factor C-Jun/Apl by the hepatitis-B virus transactivator Px occurs through a Ras-dependent and Raf-dependent signaling pathway. J Cell Biochem 1994;S18C:215-215.
    • (1994) J Cell Biochem , vol.S18C , pp. 215-215
    • Natoli, G.1    Chirillo, P.2    Avantaggiati, M.L.3    Costanzo, A.4    Ianni, A.5    Demarzio, E.6    Puri, P.7
  • 15
    • 0028135497 scopus 로고
    • Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade
    • Benn J, Schneider RJ. Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade. Proc Natl Acad Sci U S A 1994;91:10350-10354.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 10350-10354
    • Benn, J.1    Schneider, R.J.2
  • 16
    • 0027409855 scopus 로고
    • Hepatitis B virus transactivator HBx uses a tumour promoter signaling pathway
    • Kekulé AS, Lauer U, Weiss L, Luber B, Hofschneider PH. Hepatitis B virus transactivator HBx uses a tumour promoter signaling pathway. Nature 1993;361:742-745.
    • (1993) Nature , vol.361 , pp. 742-745
    • Kekulé, A.S.1    Lauer, U.2    Weiss, L.3    Luber, B.4    Hofschneider, P.H.5
  • 17
    • 0028878098 scopus 로고
    • Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation
    • Cheong JH, Yi MK, Lin Y, Murakami S. Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation. EMBO J 1995;14: 143-150.
    • (1995) EMBO J , vol.14 , pp. 143-150
    • Cheong, J.H.1    Yi, M.K.2    Lin, Y.3    Murakami, S.4
  • 18
    • 0028890351 scopus 로고
    • Hepatitis B virus transactivator protein X interacts with the TATA-binding protein
    • Qadri I, Maguire HF, Siddiqui A. Hepatitis B virus transactivator protein X interacts with the TATA-binding protein. Proc Natl Acad Sci U S A 1995;92:1003-1007.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 1003-1007
    • Qadri, I.1    Maguire, H.F.2    Siddiqui, A.3
  • 19
    • 0029034231 scopus 로고
    • HBx protein of hepatitis B virus interacts with the C-terminal portion of a novel human proteasome alpha-subunit
    • Fischer M, Runkel L, Schaller H. HBx protein of hepatitis B virus interacts with the C-terminal portion of a novel human proteasome alpha-subunit. Virus Genomes 1995;10:99-102.
    • (1995) Virus Genomes , vol.10 , pp. 99-102
    • Fischer, M.1    Runkel, L.2    Schaller, H.3
  • 20
    • 0028853994 scopus 로고
    • Hepatitis B virus X protein interacts with a probable cellular DNA repair protein
    • Lee TH, Elledge SJ, Butel JS. Hepatitis B virus X protein interacts with a probable cellular DNA repair protein. J Virol 1995;69:1107-1114.
    • (1995) J Virol , vol.69 , pp. 1107-1114
    • Lee, T.H.1    Elledge, S.J.2    Butel, J.S.3
  • 21
    • 0025890116 scopus 로고
    • Expression of the X protein of hepatitis B virus in insect cells using recombinant baculoviruses
    • Klein R, Schröder CH, Zentgraf H. Expression of the X protein of hepatitis B virus in insect cells using recombinant baculoviruses. Virus Genes 1991;5:157-174.
    • (1991) Virus Genes , vol.5 , pp. 157-174
    • Klein, R.1    Schröder, C.H.2    Zentgraf, H.3
  • 22
    • 0026349959 scopus 로고
    • A functional hepatitis B virus X protein produced in insect cells
    • Spandau DF, Wang HGH, Fraser M, Lee CH. A functional hepatitis B virus X protein produced in insect cells. Virology 1991;185:938-941.
    • (1991) Virology , vol.185 , pp. 938-941
    • Spandau, D.F.1    Wang, H.G.H.2    Fraser, M.3    Lee, C.H.4
  • 23
    • 0026005668 scopus 로고
    • Phosphorylation and rapid turnover of hepatitis B virus X-protein expressed in HepG2 cells from a recombinant vaccinia virus
    • Schek N, Bartenschlager R, Kuhn C, Schaller H. Phosphorylation and rapid turnover of hepatitis B virus X-protein expressed in HepG2 cells from a recombinant vaccinia virus. Oncogene 1991;6:1735-1744.
    • (1991) Oncogene , vol.6 , pp. 1735-1744
    • Schek, N.1    Bartenschlager, R.2    Kuhn, C.3    Schaller, H.4
  • 24
    • 12644280178 scopus 로고    scopus 로고
    • Cytoplasm is the prime compartment of hepatitis B virus X protein where it associates selectively with proteasomes
    • submitted
    • Sirma H, Rosmorduc O, Urban S, Kremsdorf D, Bréchot C. Cytoplasm is the prime compartment of hepatitis B virus X protein where it associates selectively with proteasomes. Mol Cell Biol 1997; (submitted).
    • (1997) Mol Cell Biol
    • Sirma, H.1    Rosmorduc, O.2    Urban, S.3    Kremsdorf, D.4    Bréchot, C.5
  • 29
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam JP, LeBovitz RM, Roeder RG. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acid Res 1983;11:1475-1489.
    • (1983) Nucleic Acid Res , vol.11 , pp. 1475-1489
    • Dignam, J.P.1    LeBovitz, R.M.2    Roeder, R.G.3
  • 30
    • 0023472472 scopus 로고
    • Tricine-sodium dodecyl sulfate polyacrylamide gel electrophoresis for the separation of proteins in the range from 1-100 kDa
    • Schägger H, v. Jagow G. Tricine-sodium dodecyl sulfate polyacrylamide gel electrophoresis for the separation of proteins in the range from 1-100 kDa. Anal Biochem 1987;166:368-379.
    • (1987) Anal Biochem , vol.166 , pp. 368-379
    • Schägger, H.1    V. Jagow, G.2
  • 31
    • 0021988172 scopus 로고
    • Simplified method for silver staining of proteins in polyacrylamide gels and the mechanism of silver staining
    • Heukeshoven J, Dernick R. Simplified method for silver staining of proteins in polyacrylamide gels and the mechanism of silver staining. Electrophoresis 1985;6:103-112.
    • (1985) Electrophoresis , vol.6 , pp. 103-112
    • Heukeshoven, J.1    Dernick, R.2
  • 35
    • 0029815105 scopus 로고    scopus 로고
    • Isolation of highly purified, functional carboxy-terminally truncated hepatitis B virus middle surface protein activators from eucaryotic expression systems
    • Hildt E, Urban S, Eckerskorn C, Hofschneider PH. Isolation of highly purified, functional carboxy-terminally truncated hepatitis B virus middle surface protein activators from eucaryotic expression systems. HEPATOLOGY 1996;24:502-507.
    • (1996) Hepatology , vol.24 , pp. 502-507
    • Hildt, E.1    Urban, S.2    Eckerskorn, C.3    Hofschneider, P.H.4
  • 36
    • 0026625616 scopus 로고
    • Alternate translation initiation on hepatitis B virus X mRNA produces multiple polypeptides that differentially transactivate class II and III promoters
    • Kwee L, Lucito R, Aufiero B, Schneider RJ. Alternate translation initiation on hepatitis B virus X mRNA produces multiple polypeptides that differentially transactivate class II and III promoters. J Virol 1992;66(7): 4382-4389.
    • (1992) J Virol , vol.66 , Issue.7 , pp. 4382-4389
    • Kwee, L.1    Lucito, R.2    Aufiero, B.3    Schneider, R.J.4
  • 37
    • 0029147911 scopus 로고
    • The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of ras and nuclear activator of transcription factors
    • Doria M, Klein N, Lucito R, Schneider RJ. The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of ras and nuclear activator of transcription factors. EMBO J 1995;14:4747-4757.
    • (1995) EMBO J , vol.14 , pp. 4747-4757
    • Doria, M.1    Klein, N.2    Lucito, R.3    Schneider, R.J.4
  • 38
    • 0029087168 scopus 로고
    • Assignment of disulfide bonds in the X protein (HBx) of hepatitis B virus
    • Gupta A, Mal TK, Jayasuryan N, Chauhan VS. Assignment of disulfide bonds in the X protein (HBx) of hepatitis B virus. Biochem Biophys Res Comm 1995;212:919-924.
    • (1995) Biochem Biophys Res Comm , vol.212 , pp. 919-924
    • Gupta, A.1    Mal, T.K.2    Jayasuryan, N.3    Chauhan, V.S.4
  • 40
    • 0026549687 scopus 로고
    • Identification of three essential regions of Hepatitis B virus X protein for transactivation function
    • Arii M, Takada S, Koike K. Identification of three essential regions of Hepatitis B virus X protein for transactivation function. Oncogene 1992; 7:397-403.
    • (1992) Oncogene , vol.7 , pp. 397-403
    • Arii, M.1    Takada, S.2    Koike, K.3
  • 41
    • 0347483867 scopus 로고
    • Expression of the hepatitis B virus X gene in mammalian cells
    • Siddiqui A, Jameel S, Mapoles J. Expression of the hepatitis B virus X gene in mammalian cells. Proc Natl Acad Sci U S A 1987;84:2513-2517.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 2513-2517
    • Siddiqui, A.1    Jameel, S.2    Mapoles, J.3
  • 42
    • 0025070345 scopus 로고
    • Hepatitis B virus (HBV) X gene expression in human cells and anti-HBx antibodies detected in chronic HBV infection
    • Levrero M, Jean-Jean O, Balsano C, Will H, Perricaudett M. Hepatitis B virus (HBV) X gene expression in human cells and anti-HBx antibodies detected in chronic HBV infection. Virology 1990;174:299-304.
    • (1990) Virology , vol.174 , pp. 299-304
    • Levrero, M.1    Jean-Jean, O.2    Balsano, C.3    Will, H.4    Perricaudett, M.5


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