Formulation and evaluation of a two-components lyophilized kit for Tc- sestamibi: Transchelation preparation of Tc-99m-sestamibi

Nuclear Medicine and Biology

Volumn 24, Issue 7, 1997, Pages 697-700

  Pandey, P M ^a   Sachdev, S S ^a   Ramamoorthy, N ^a,c   Lal, R ^a   Ranganatha, D K ^a   Narasimhan, S ^b   Oommen, R ^b   Gunasekaran, S ^b   Nair, N A ^b  

^a Bd of Radiat/Isotope Technology   (India)

^b CHRISTIAN MEDICAL COLLEGE   (India)

^c DEPARTMENT OF ATOMIC ENERGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CITRATE SODIUM; GLUCOHEPTONIC ACID; MANNITOL; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; PERTECHNETIC ACID TC 99M; STANNOUS CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; CHELATION; CONTROLLED STUDY; DOG; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG PURITY; DRUG SCREENING; DRUG SYNTHESIS; FREEZE DRYING; HEART SCINTISCANNING; IMAGE QUALITY; INTRAVENOUS DRUG ADMINISTRATION; MONKEY; NONHUMAN; RABBIT; RAT;

ANIMALS; CHELATING AGENTS; DOGS; DRUG STABILITY; FREEZE DRYING; HAPLORHINI; HEART; LIGANDS; RABBITS; RADIOPHARMACEUTICALS; RATS; RATS, WISTAR; REAGENT KITS, DIAGNOSTIC; TECHNETIUM TC 99M SESTAMIBI;

EID: 0030847914     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(97)00082-6     Document Type: Article

References (12)

1. 99mTc-MIBI. Nucl. Med. Biol. 22, 585-588.
2. Cardiolite product literature, The Dupont Merck Pharmaceutical Co., USA.
3. 3 as a hippuran replacement. J. Nucl. Med. 27, 111-116.
4. Hoffman P., Gokel G., Marquarding D. and Ugi I. (1971) Isonitrile syntheses. In: Isonitrile Chemistry (Edited by Ugi I.), pp. 9-40, Academic Press, New York.
5. 99mTc-TBI): Initial experience in human. J. Nucl. Med. 25, 1350-1355.
6. Okada R. D., Grover D., Gaffney T. B. S. and Williams S. (1988) Myocardial kinetics of technetium-99m hexakis 2-methoxy-2-methyl-propyl isonitrile. Circulation 77, 491-498.
7. Pandey P. M., Sachdev S. S., Ramamoorthy N., Lal R. and Ranganatha D. K. (1995) Formulation and evaluation of a two-components kit for Tc-99m-MIBI. Ind. J. Nucl. Med. 9,(4), 210 (Abstract).
8. Production of Tc-99m radiopharmaceuticals for brain, heart and kidney imaging (1995). IAEA Technical Document 805.
9. 99mTc-2-Methoxy isobutyl isonitrile (Tc-MIBI) for myocardial imaging: Process development experience at BRIT. Ind. J. Nucl. Med. 9(1), 63 (Abstract).
10. 99mTc-TBI) for myocardial imaging: Kit for hospital radiopharmacy. Nucl. Med. Biol. 17, 543-552.
11. 99mTc Ethoxymethylpropyl isonitrile: A radioactive tracer for myocardial perfusion imaging. Nucl. Med. Biol. 16, 455-459.
12. Wackers F. J. T., Berman D. S., Maddahi J., Watson D. D., Beller G. A., Strauss H. W. et al. (1989) Technetium-99m hexakis 2-methoxy isobutyl isonitrile: Human biodistribution, dosimetry, safety and preliminary comparison to thallium-201 for myocardial perfusion imaging. J. Nucl. Med. 30, 301-311.