CQ-397 and CQ-414: Antimicrobial activity and spectrum of two fluoroquinolone-cephalosporin, dual-action compounds with carboxamido bonds

Clinical Microbiology and Infection

Volumn 3, Issue 3, 1997, Pages 335-344

  Johnson, David M ^a   Jones, Ronald N ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Dual action compounds; Enrofloxacin; Norfloxacin; Older cephalosporins

Indexed keywords

CEFAMANDOLE; CEFAMANDOLE PLUS ENROFLOXACIN; CEFAMANDOLE PLUS NORFLOXACIN; CEPHALOSPORIN DERIVATIVE; CQ 397; CQ 414; ENROFLOXACIN; NORFLOXACIN; OXACILLIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; ARTICLE; CITROBACTER FREUNDII; CONTROLLED STUDY; DILUTION; DRUG ACTIVITY; DRUG MIXTURE; ENTEROBACTERIACEAE; ENTEROCOCCUS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HAEMOPHILUS INFLUENZAE; MINIMUM INHIBITORY CONCENTRATION; MORAXELLA CATARRHALIS; NONHUMAN; PRIORITY JOURNAL; PROVIDENCIA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STENOTROPHOMONAS MALTOPHILIA;

ANIMALIA; ARACHNIS X VANDA; BACTERIA (MICROORGANISMS); CITROBACTER FREUNDII; ENTEROBACTERIACEAE; ENTEROCOCCUS; HAEMOPHILUS INFLUENZAE; MORAXELLA CATARRHALIS; NEGIBACTERIA; POSIBACTERIA; PROVIDENCIA; STAPHYLOCOCCI; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STENOTROPHOMONAS MALTOPHILIA;

EID: 0030847131     PISSN: 1198743X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-0691.1997.tb00623.x     Document Type: Article

References (7)

1. Hamilton-Miller JMT. Dual-action antibiotic hybrids. J Antimicrob Chemother 1994; 33: 197-200.
2. Georgopapadakou NH, Bertasso A, Chan KK, et al. Mode of action of the dual-action cephalosporin Ro23-9424. Antimicrob Agents Chemother 1989; 33: 1067-71.
3. Jones RN, Barry AL, Thornsberry C. Antimicrobial activity of Ro23-9424, a novel ester-linked co-drug of fleroxacin and desacerylcefotaxime. Antimicrob Agents Chemother 1989; 33: 944-50.
4. Beskid G, Fallat V, Lipschitz ER, et al. In vitro activities of a dual-action antibacterial agent Ro23-9424, and comparative agents. Antimicrob Agents Chemother 1989; 33: 1072-7.
5. Jones RN, Sanchez ML. Antimicrobial activity of a new antipseudomonal dual-action drug, Ro25-0534. Diagn Microbiol Infect Dis 1994; 18: 61-8.
6. National Committee of Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility testing. Supplemental tables, M100-S6. Villanova, PA: NCCLS, 1995.
7. National Committee for Clinical Laboratory Standards. Approved standard M7-A3: standard methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Villanova, PA: NCCLS, 1993.