Double-positive T cell receptor(high) thymocytes are resistant to peptide/major histocompatibility complex ligand-induced negative selection

European Journal of Immunology

Volumn 27, Issue 9, 1997, Pages 2279-2289

  Ghendler, Yoseph ^a,c   Hussey, Rebecca E ^a,c   Witte, Torsten ^a,c   Mizoguchi, Emiko ^b,c   Clayton, Linda K ^a,c   Bhan, Atul K ^b,c   Koyasu, Shigeo ^a,c   Chang, Hsiu Chiang ^a,c   Reinherz, Ellis L ^a,c  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Differentiation; T cell receptor; Thymic selection

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; OCTAPEPTIDE; T LYMPHOCYTE RECEPTOR; VIRUS PROTEIN;

APOPTOSIS; ARTICLE; CYTOTOXIC T LYMPHOCYTE; LYMPHOCYTE DIFFERENTIATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; ONTOGENY; PRIORITY JOURNAL; THYMOCYTE; TRANSGENIC MOUSE; VESICULAR STOMATITIS VIRUS;

ANIMALS; ANTIGENS, VIRAL; APOPTOSIS; CD8-POSITIVE T-LYMPHOCYTES; DNA-BINDING PROTEINS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DEPLETION; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PEPTIDES; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, CYTOTOXIC; THYMUS GLAND; VESICULAR STOMATITIS-INDIANA VIRUS;

EID: 0030846580     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830270923     Document Type: Article

References (69)

1. Chein, Y., Becker, D. M., Lindsten, T., Okamura, M., Cohen, D. I. and Davis, M. M., Nature 1984. 312: 31.
2. Hedrick, S. M., Cohen, D. I., Nielsen, E. A. and Davis, M. M., Nature 1984. 308: 149.
3. Saito, H., Kranz, D. M., Takagaki, Y., Hayday, A. C., Eisen, H. N. and Tonegawa, S., Nature 1984. 312: 36.
4. Yoshikai, Y., Anatonioui, D., Clark, S. P., Yanagi, Y., Sangster, R., van den Elsen, P., Terhorst, C. and Mak, T. W., Nature 1984. 312: 521.
5. Davis, M. M. and Bjorkman, P. J., Nature 1988. 334: 395.
6. Fowlkes, B. J. and Pardoll, D. M., Adv. Immunol. 1989. 44: 207.
7. Nossal, G. J. V., Cell 1994. 76: 229.
8. Bevan, M. J., Nature 1977. 269: 417.
9. Zinkernagel, R. M., Callahan, G. N., Althage, A., Cooper, S., Klein, P. A. and Klein, J., J. Exp. Med. 1978. 147: 882.
10. Berg, L. J., Pullen, A. M., Fazekas de St. Groth, B., Mathis, D., Benoist, C. and Davis, M. M., Cell 1989. 58: 1035.
11. von Boehmer, H., Cell 1994. 76: 219.
12. Fowlkes, B. J. and Schweighoffer, E., Curr. Opin. Immunol. 1995. 7: 188.
13. Jameson, S. C., Hogquist, K. A. and Bevan, M. J., Annu. Rev. Immunol. 1995. 13: 93.
14. Ramarli, D., Fox, D. A. and Reinherz, E. L., Proc. Natl. Acad. Sci. USA 1987. 84: 8598.
15. Kappler, J. W., Roehm, N. and Marrack, P., Cell 1987. 49: 273.
16. Fowlkes, B. J., Schwartz, R. H. and Pardoll, D. M., Nature 1988. 334: 620.
17. Kisielow, P., Bluthmann, H., Staerz, U. D., Steinmetz, M. and von Boehmer, H., Nature 1988. 333: 742.
18. Murphy, K. M., Heimberger, A. B. and Loh, D. Y., Science 1990. 250: 1720.
19. Vasquez, N. J., Kaye, J. and Hedrick, S. M., J. Exp. Med. 1992. 175: 1307.
20. Sebzda, E., Wallace, V. A., Mayer, J., Yeung, R. S. M., Mak, T. W. and Ohashi, P. S., Science 1994. 263: 1615.
21. Ashton-Rickardt, P. G., Bandeira, A., Delaney, J. R., Van Kaer, L., Pircher, H.-P., Zinkernagel, R. M. and Tonegawa, S., Cell 1994. 76: 651.
22. Hogquist, K. A., Jameson, S. C., Heath, W. R., Howard, J. L., Bevan, M. J. and Carbone, F. R., Cell 1994. 76: 17.
23. Mamalaki, C., Norton, T., Tanaka, Y., Townsend, A. R., Chandler, P., Simpson, E. and Kioussis, D., Proc. Natl. Acad. Sci. USA 1992. 89: 11342.
24. Berg, L. J., Frank, G. D. and Davis, M. M., Cell 1990. 60: 1043.
25. Koller, B. H., Marrack, P., Kappler, J. W. and Smithies, O., Science 1990. 248: 1227.
26. Huesmann, M., Scott, B., Kisielow, P. and von Boehmer, H., Cell 1991. 66: 533.
27. Ohashi, P. S., Pircher, H., Burki, K., Zinkernagel, R. M. and Hengartner, H., Nature 1990. 346: 861.
28. Borgulya, P., Kishi, H., Muller, U., Kirberg, J. and von Boehmer, H., EMBO J. 1991. 10: 913.
29. Chan, A. C., Kadlecek, T. A., Elder, M. E., Filipovich, A. H., Kuo, W. L., Iwashima, M., Parslow, T. G. and Weiss, A., Science 1994. 264: 1599.
30. Shortman, K., Vremec, D. and Egerton, M., J. Exp. Med. 1991. 173: 323.
31. Lucas, B., Vasseur, F. and Penit, C., J. Immunol. 1993. 151: 4574.
32. Lucas, B., Vasseur, F. and Penit, C., J. Immunol. 1994. 153: 53.
33. Petrie, H. T., Strasser, A., Harris, A. W., Hugo, P. and Shortman, K., J. Immunol. 1993. 151: 1273.
34. Kisielow, P. and Miazek, A., J. Exp. Med. 1995. 181: 1975.
35. Shibata, K.-I., Imarai, M., van Bleek, G. M., Joyce, S. and Nathenson, S. G., Proc. Natl. Acad. Sci. USA 1992. 89: 3135.
36. Shinkai, Y., Rathbun, G., Lam, K.-P., Oltz, E. M., Stewart, V., Mendelsohn, M., Charron, J., Datta, M., Young, F., Stall, A. M. and Alt, F. W., Cell 1992. 68: 855.
37. Shinkai, Y., Koyasu, S., Nakayama, K., Murphy, K. M., Loh, D. Y., Reinherz, E. L. and Alt, F. W., Science 1993. 259: 822.
38. Chang, H.-C., Bao, Z.-Z., Yao, Y., Tse, A. G. D., Goyarts, E. C., Madsen, M., Kawasaki, E., Brauer, P. P., Sacchettini, J. C., Nathenson, S. G. and Reinherz, E. L., Proc. Natl. Acad. Sci. USA 1994. 91: 11408.
39. Patten, P. A., Rock, E. P., Sonoda, T., Fazekas de St. Groth, B., Jorgensen, J. L. and Davis, M. M., J. Immunol. 1993. 150: 2281.
40. Hogan, B., Beddington, R., Costantini, F. and Lacy, E., Manipulating the mouse embryo. A laboratory manual, 2nd Edn., Cold Spring Harbor Laboratory Press, Cold Spring Harbor 1994.
41. Mombaerts, P., Mizoguchi, E., Grusby, M. J., Glimcher, L. H., Bhan, A. K. and Tonegawa, S., Cell 1993. 75: 275.
42. Gavrieli, Y., Sherman, Y. and Ben-Sasson, S. A., J. Cell. Biol. 1992. 119: 493.
43. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. C., Smith, J. A. and Struhl, K., Current Protocols in Molecular Biology, Wiley, New York 1989.
44. Liu, Z.-G., Smith, S. W., Mclaughlin, K. A., Schwartz, L. M. and Osborne, B. A., Nature 1994. 367: 281.
45. Woronicz, J. D., Calnan, B., Ngo, V. and Winoto, A., Nature 1994. 367: 277.
46. Surh, C. D. and Sprent, J., Nature 1994. 372: 100.
47. Kraal, G., Breel, M., Janse, M. and Bruin, G., J. Exp. Med. 1986. 163: 981.
48. Jameson, S. C., Hogquist, K. A. and Bevan, M. J., Nature 1994. 369: 750.
49. Hogquist, K. A., Jameson, S. C. and Bevan, M. J., Immunity 1995. 3: 79.
50. Sebzda, E., Kundig, T. M., Thomson, C. T., Aoki, K., Mak, S.-Y., Mayer, J. P., Zamborelli, T., Nathenson, S. G. and Ohashi, P. S., J. Exp. Med. 1996. 183: 1093.
51. Swat, W., Ignatowicz, L., von Boehmer, H. and Kisielow, P., Nature 1991. 351: 150.
52. Iwabuchi, K., Nakayama, K.-I., McCoy, R. L., Wang, F., Nishimura, T., Habu, S., Murphy, K. M. and Loh, D. Y., Proc. Natl. Acad. Sci. USA 1992. 89: 9000.
53. Jameson, S. C., Hogquist, K. A. and Bevan, M. J., Annu. Rev. Immunol. 1995. 13: 93.
54. Janeway, C. A., Immunol. Today 1995. 16: 223.
55. Janeway, C. A., Medhzhitov, R., Pfeiffer, C., Tao, X. and Bottomly, K., The Immunologist 1995. 3/2: 41.
56. Jameson, S. C. and Bevan, M. J., Immunity 1995. 2: 1.
57. Ashton-Rickardt, P. G., Van Kaer, L., Schumacher, T. N. M., Ploegh, H. L. and Tonegawa, S., Cell 1993. 73: 1041.
58. Ignatowicz, L., Kappler, J. and Marrack, P., Cell 1996. 84: 521.
59. Munir Alam, S., Travers, P. J., Wung, J. L., Nasholds, W., Redpath, S., Jameson, S. C. and Gascoigne, R. J., Nature 1996. 381: 616.
60. Takahama, Y., Shores, E. W. and Singer, A., Science 1992. 258: 653.
61. Spain, L. M. and Berg, L. J., J. Exp. Med. 1992. 176: 213.
62. Choi, Y., Herman, A., DiGiusto, D., Wade, T., Marrack, P. and Kappler, J., Nature 1990. 346: 471.
63. Pullen, A., Wade, T., Marrack, P. and Kappler, J. W., Cell 1990. 61: 1365.
64. Malchiodi, E. L., Eisenstein, E., Fields, B. A., Ohlendorf, D. H., Schlievert, P. M., Karjalainen, K. and Mariuzza, R. A., J. Exp. Med. 1995. 182: 1833.
65. O'Rourke, A. M., Mescher, M. F. and Webb, S. R., Science 1990. 249: 171.
66. Calnan, B. J., Szychowski, S., Chan, F. K.-M., Cado, D. and Winoto, A., Immunity 1995. 3: 273.
67. Lee, S. L., Wesselschmidt, R. L., Linette, G. P., Kanagawa, O., Russel, J. H. and Milbrandt, J., Science 1995. 269: 532.
68. Singer, G. G. and Abbas, A. K., Immunity 1994. 1: 365.
69. Henkart, P. A., Immunity 1996. 4: 195.