Distinct agonist-mediated endocytosis of cloned rat somatostatin receptor subtypes expressed in insulinoma cells

Journal of Neuroendocrinology

Volumn 9, Issue 10, 1997, Pages 741-751

  Roosterman, Dirk ^a   Roth, Adelheid ^b   Kreienkamp, Hans Jürgen ^b   Richter, Dietmar ^b   Meyerhof, Wolfgang ^b,c  

^a Deutsches Inst F E   (Germany)

^b UNIVERSITY OF POTSDAM   (Germany)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Desensitization; Endocytosis; Internalization; Neuropeptide receptor; Somatostatin

Indexed keywords

ARSENOSOBENZENE; BAFILOMYCIN A1; BREFELDIN A; CELL SURFACE RECEPTOR; CLATHRIN; COMPLEMENTARY DNA; CYCLOHEXIMIDE; LIGAND; MONENSIN; OCTREOTIDE; PEPTIDE; RECEPTOR SUBTYPE; SOMATOSTATIN 14; SOMATOSTATIN 28; SOMATOSTATIN RECEPTOR; SUCROSE;

ANIMAL CELL; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL SURFACE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOCYTOSIS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INSULINOMA; MEMBRANE VESICLE; MOLECULAR CLONING; NEUROENDOCRINE TUMOR; NONHUMAN; PALLIATIVE THERAPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION; TEMPERATURE; TUMOR CELL;

EID: 0030845776     PISSN: 09538194     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2826.1997.00632.x     Document Type: Article

References (45)

1. Reichlin S. Somatostatin. New Engl J Med 1983; 309: 1495-1501.
2. Epelbaum J, Dournaud P, Fodor M, Violett C. The neurobiology of somatostatin. Crit Ret Neurobiol 1994; 8: 25-44.
3. Bell GI, Reisine T. Molecular biology of somatostatin receptors. Trends Neurosci 1993; 16: 34-38.
4. Hoyer D, Lübbert H, Bruns C. Molecular pharmacology of somatostatin receptors. NS Arch Pharmacol 1994; 350: 441-453.
5. Wulfsen I, Meyerhof W, Fehr S, Richter D. Expression patterns of rat somatostatin receptor genes in pre-and postnatal brain and pituitary. J Neurochem 1993; 61: 1549-1552.
6. Reisine T, Bell GI. Molecular biology of somatostatin receptors. Endocrinology 1995; 16: 427-442.
7. Hartmann D, Fehr S, Meyerhof W, Richter D. Distribution of somatostatin receptor subtype 1 mRNA in the developing cerebral hemispheres of the rat. Dev Neurosci 1995; 17: 246-255.
8. Vanetti M, Kouba M, Wang X, Vogt G, Höllt V. Cloning and expression of a novel mouse somatostatin receptor (SSTR2B). FEBS Lett 1992; 311: 290-294.
9. Lamberts SWJ, Koper JW, Reubi J-C. Potential role of somatostatin analogues in the treatment of cancer. Eur J Clin Invest 1987; 17: 281-287.
10. De Herder WW, Lamberts SW. Imagine of pituitary tumours. Baillieres J Clin Endocr Metab 1995; 9: 367-389.
11. Krenning EP, Bakker WH, Kooij PP, et al. Somatostatin receptor scintigraphy with indium-111-DTPA-D-Phe-1-octreotide in man: metabolism, dosimetry and comparison with iodine-123-Tyr-3-octreotide. J Nucl Med 1992; 33: 652-658.
12. Hofland LJ, Visser Wisselaar HA, Lamberts SW. Somatostatin analogs: clinical application in relation to human somatostatin receptor subtypes. Biochem Pharmacol 1995; 50: 287-297.
13. Yang IM, Woo JT, Kim SW, Kim JW, Kim YS, Choi YK. Characteristics of acromegalic patients with a good response to octreotide, a somatostatin analogue. Clin Endocrinol 1995; 42: 295-301.
14. Weckbecker G, Raulf F, Stolz B, Bruns C. Somatostatin analogs for diagnosis and treatment of cancer. Pharmacol Therapeut 1993; 60: 245-264.
15. Scherübl H, Bäder M, Fett U, Hamm B, Schmidt-Sayk H, Koppenhagen K, Dop M, Riecken EO, Wiedenmann B. Somatostatin-receptor imaging of neuroendocrine gastroentero-pancreatic tumors. Gastroenterology 1993; 105: 1705-1709.
16. Bruns C, Stolz B, Albert R, Marbach P, Pless J. OctreoScan 111 for imaging of a somatostatin receptor-positive islet cell tumor in rat. Horm Metab Res Suppl 1993; 27: 5-11.
17. Bakker WH, Albert R, Bruns C, Breeman WA, Hofland LJ, Marbach P, Pless J, Pralet D, Stolz B, Koper JW, Lamberts SWJ, Kisser TJ, Krenning EP. [111In-DTPA-D-Phe1]-octreotide, a potential radiopharmaceutical for imaging of somatostatin receptorpositive tumors: synthesis, radiolabeling and in vitro validation. Life Sci 1991; 49: 1583-1591.
18. Haraguchi K, Ohtaka M, Takazawa K, Endo T, Onaya T. Desensitization to somatostatin analogue (Octreotide) observed in a patient with acromegaly. Endocr J 1995; 42: 295-300.
19. Bertherat J, Chanson P, Dewailly D, Enjalbert A, Juquet P, Kordon C, Peillon F, Timsit J, Epelbaum J. Resistance to somatostatin (SRIH) analog therapy in acromegaly. Re-evaluation of the correlation between the SRIH receptor status of the pituitary tumor and the in vivo inhibition of GH secretion in response to SRIH analog. Horm Res 1992; 38: 94-99.
20. Wang H-L, Dichter M, Reisine T. Lack of cross-desensitization of somatostatin-14 and somatostatin-28 receptors coupled to potassium channels in rat neocortical neurons. Mol Pharmacol 1990; 38: 357-361.
21. Reisine T, Axelrod J. Prolonged somatostatin pretreatment desensitizes somatostatin inhibition of receptor-mediated release of adrenocorticotropin and sensitizes adenylyl cyclase. Endocrinology 1983; 113: 811-813.
22. Reisine T. Somatostatin desensitization: loss of the ability of somatostatin to inhibit cAMP accumulation and adrenocorticotropin release. J Pharmacol Exp Therapeut 1984; 229: 14-20.
23. 1 pituitary cells and does not reduce cellular responsiveness to somatostatin. J Biol Chem 1988; 263: 714-723.
24. Reisine T, Kong H, Raynor K, Yano H, Takeda J, Yasuda K, Bell GI. Splice variant of the somatostatin receptor 2 subtype, somatostatin receptor 2B, couples to adenylyl cyclase. Mol Pharmacol 1993; 44: 1016-1020.
25. Vanetti M, Vogt G, Höllt V. The two isoforms of the mouse somatostatin receptor (mSSTR2A and mSSTR2B) differ in coupling efficiency to adenylate cyclase and in agonist-induced receptor desensitization. FEBS Lett 1993; 331: 260-266.
26. Yasuda K, Rens-Domiano S, Breder CD et al. Cloning of a novel somatostatin receptor, SSTR3, coupled to adenylyl cyclase. J Biol Chem 1992; 267: 20422-20428.
27. Raynor K, O'Carroll A-M, Kong H, Yasuda K, Mahan LC, Bell GI, Reisine T. Characterization of cloned comatostatin receptors SSRT4 and SSTR5. Mol Pharmacol 1993; 44: 385-392.
28. Hukovic N, Panetta R, Kumar U, Patel YC. Agonist-dependent regulation of cloned human somatostatin receptor types 1-5 (hSSTR1-5): subtype selective internalization or upregulation. Endocrinology 1996; 137: 4046-4049.
29. Nouel D, Gaudriault G, Houle M et al. Differential internalization of somatostatin in COS-7 cells transfected with SST1 and SST2 receptor subtypes: a confocal microscopic study using novel fluorescent somatostatin derivatives. Endocrinology 1997; 188: 1-11.
30. Roth A, Kreienkamp H-J, Nehring RB, Roosterman D, Meyerhof W, Richter D. Endocytosis of the rat somatostatin receptors: subtype discrimination, ligand specificity, and delineation of carboxyl terminal positive and negative sequence motifs. DNA Cell Biol 1997; 16: 111-119.
31. Klausner RD, Donaldson JG, Lippincott-Schwartz J, Brefeldin A. Insiahts into the control of membrane traffic and organelle structure. J Cell Biol 1992; 116: 1071-1080.
32. John M, Meyerhof W, Richter D, Waser B, Schaer JC, Scherubl H, Boese Landgraf J, Neuhans P, Ziske C, Molling K, Riecken EO, Reubi JC, Wiedenmann B. Positive somatostatin receptor scintigraphy correlates with the presence of somatostatin receptor subtype 2. Gut 1996; 38: 33-39.
33. 3) octreotide by mouse and human pituitary tumor cells: increase by unlabeled octreotide. Endocrinulogy 1995; 136: 3698-3706.
34. Epelbaum J, Bertherat J, Prevost G, Kordon C, Meyerhof W, Wulfsen I, Richter D, Plouin P-F. Molecular and pharmacological characterization of somatostatin receptor subtypes in adrenal, extraadrenal, and malignant pheochromocytomas. J Clin Endocr Metab 1995; 80: 1837-1844.
35. Invitti C, De Martin I, Bolla GB, Pecori Giraldi F, Maestri E, Leonetti G, Cavagnini F. Effect of octreotide on catecholamine plasma levels in patients with chromaffin cell tumors. Horm Res 1993; 40: 156-160.
36. Plouin PF, Bertherat J, Chatellier G, Billaud E, Azizi M, Grouzmann E, Epelbaum J. Short-term effects of octreotide on blood pressure and plasma catecholamines and neuropeptide Y levels in patients with phaeochromocytoma: a placebo-controlled trial. Clin Endocrinol 1995; 42: 289-294.
37. Breder CD, Yamada Y, Yasuda K, Seino S, Saper CB, Bell GI. Differential expression of somatostatin receptor subtypes in brain. J Neurosci 1992; 12: 3920-3934.
38. Raulf F, Ferez J, Hoyer D, Bruns C. Differential expression of five somatostatin receptor subtypes, SSTR 1-5, in the CNS and peripheral tissue. Digestion 1994; 3: 46-53.
39. 2A in rat brain using a specific anti-peptide antibody. J Neurosci 1996; 16: 4468-4478.
40. Meyerhof W, Paust HJ, Schonrock C, Richter D. Cloning of a cDNA encoding a novel putative G-protein-coupled receptor expressed in specific rat brain regions. DNA Cell Biol 1991; 10: 689-694.
41. Kluxen FW, Bruns C, Lübbert H. Expression cloning of a rat brain somalostatin receptor cDNA. Proc Natl Acda Sci USA 1992; 89: 4618-4622.
42. Meyerhof W, Wulfsen I, Schönrock C, Fehr S, Richter D. Molecular cloning of a somatostatin-28 receptor and comparison of its expression pattern with that of a somatostatin-14 receptor in rat brain. Proc Natl Acad Sci USA 1992; 89: 10267-10271.
43. Bruno JF, Xu Y, Song J, Berelowitz M. Molecular cloning and functional expression of a brain-specific somatostatin receptor. Proc Natl Acad Sci USA 1992; 89: 11151-11155.
44. O'Carroll A-M, Lolait SJ, König M, Hahan LC, Molecular cloning and expression of a pituitary somatostatin receptor with preferential affinity for somatostatin-28. Mol Pharmacol 1992; 42: 939-946.
45. Grady EF, Slices LW, Brant WO, Walsh JH, Payan DG, Bunnett NW. Direct observation of endocytosis of gastrin releasing peptide and its receptor. J Biol Chem 1995; 270: 4603-4611.