A new T-lymphocyte cloning assay for detection of in vivo mutations in the human hypoxanthine-guanine phosphoribosyltransferase gene

Environmental and Molecular Mutagenesis

Volumn 30, Issue 1, 1997, Pages 31-39

  Uematsu, Kazutsugu ^a,c   Yasuda, Jun ^a   Sekine, Teruaki ^a   Sugano, Kokichi ^b   Kudoh, Shoji ^c   Sekiya, Takao ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b NATIONAL CANCER CENTER HOSPITAL   (Japan)

^c NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Anti CDB monoclonal antibody; Hereditary nonpolyposis colon cancer (HNPCC); Hypoxanthine guanine phosphoribosyltransferase (hprt) gene; In viva mutation frequency; Single strand conformation polymorphism nonpolyposis (HNPCC) (SSCP) analysis

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MONOCLONAL ANTIBODY CD3;

ARTICLE; CLINICAL ARTICLE; COLON CANCER; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; MALE; MOLECULAR CLONING; MUTAGEN TESTING; MUTATION RATE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; SINGLE STRAND CONFORMATION POLYMORPHISM; T LYMPHOCYTE;

ADULT; CLONING, MOLECULAR; COLONIC NEOPLASMS; DNA MUTATIONAL ANALYSIS; FEMALE; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; RNA, MESSENGER; RNA-DIRECTED DNA POLYMERASE; T-LYMPHOCYTES; TUMOR CELLS, CULTURED;

EID: 0030845549     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2280(1997)30:1<31::AID-EM5>3.0.CO;2-F     Document Type: Article

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