Limitations of reverse-transcriptase polymerase chain reaction analyses for detection of micrometastatic epithelial cancer cells in bone marrow

Journal of Clinical Oncology

Volumn 15, Issue 7, 1997, Pages 2701-2708

  Zippelius, A ^a   Kufer, P ^a   Honold, G ^a   Kollermann M W ^a   Oberneder, R ^a   Schlimok, G ^a   Riethmuller G ^a   Pantel, K ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; DESMOPLAKIN; GLYCOPROTEIN; PROSTATE SPECIFIC ANTIGEN;

ARTICLE; BONE MARROW METASTASIS; BREAST CARCINOMA; CANCER CELL; CANCER LOCALIZATION; CELLULAR DISTRIBUTION; DIAGNOSTIC ACCURACY; GENE EXPRESSION REGULATION; HUMAN; MAJOR CLINICAL STUDY; MARKER GENE; PRIORITY JOURNAL; PROSTATE CARCINOMA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0030845046     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1997.15.7.2701     Document Type: Article

References (38)

1. Devesa SS, Blot WJ, Stone BJ, et al: Recent cancer trends in the United States. J Natl Cancer Inst 87:175-182, 1995
2. Frost P, Levin B: Clinical implications of metastatic process. Lancet 339:1458-1461, 1992
3. Cote RJ, Rosen PP, Lesser ML, et al: Prediction of early relapse in patients with operable breast cancer by detection of occult bone marrow micrometastases. J Clin Oncol 9:1749-1756, 1991
4. Lindemann F, Schlimok G, Dirschedl P, et al: Prognostic significance of micrometastatic tumour cells in bone marrow of colorectal cancer patients. Lancet 340:685-689, 1992
5. Jauch KW, Heiss MM, Gruetzner U: Prognostic significance of bone marrow micrometastases in patients with gastric cancer. J Clin Oncol 14:1810-1817, 1996
6. Pantel K, Aignherr C, Köllermann J, et al: Immunocytochemical detection of isolated tumor cells in bone marrow of patients with untreated stage C prostatic cancer. Eur J Cancer 31A: 1627-1632, 1995
7. Pantel K, Izbicki J, Passlick B, et al: Frequency and prognostic significance of isolated tumour cells in bone marrow of patients with non-small-cell lung cancer without overt metastases. Lancet 347:649-653, 1996
8. Seiden MV, Kantoff PW, Krithivas K, et al: Detection of circulating tumor cells in men with localized prostate cancer. J Clin Oncol 12:2634-2639, 1994
9. Israeli RS, Miller WH Jr, Su SL, et al: Sensitive nested reverse transcription polymerase chain reaction detection of circulating prostatic tumor cells: Comparison of prostate-specific membrane antigen and prostate-specific antigen-based assays. Cancer Res 54:6306-6310, 1994
10. Wood DP Jr, Banks ER, Humphreys S, et al: Sensitivity of immunohistochemistry and polymerase chain reaction in detecting prostate cancer cells in bone marrow. J Histochem Cytochem 42:505-511, 1994
11. Katz AE, deVries BS, Begg MD, et al: Enhanced reverse transcriptase-polymerase chain reaction for prostate specific antigen as an indicator of true pathologic stage in patients with prostate cancer. Cancer 75:1642-1648, 1995
12. Datta YH, Adams PT, Drobyski WR: Sensitive detection of occult breast cancer by the reverse-transcriptase polymerase chain reaction. J Clin Oncol 12:475-482, 1994
13. Gerhard M, Juhl H, Kalthoff H, et al: Specific detection of carcinoembryonic antigen-expressing tumor cells in bone marrow aspirates by polymerase chain reaction. J Clin Oncol 12:725-729, 1994
14. Raykumar T, Gullick WJ: The type I growth factor receptors in human breast cancer. Breast Cancer Res Treat 29:3-9, 1994
15. Thompson J, Zimmermann W: The carcinoembryonic antigen gene family: Structure, expression and evolution. Tumor Biol 9:63-83, 1988
16. Litvinov SV, Velders MP, Bakker HAM, et al: Ep-CAM: A human epithelial antigen is a homophilic cell-cell adhesion molecule. J Cell Biol 125:437-446, 1994
17. Garrod DR: Desmosomes and cancer. Cancer Surv 24:97-111, 1995
18. Israeli RS, Powell T, Corr JG, et al: Expression of prostate-specific membrane antigen. Cancer Res 54:1807-1811, 1994
19. Brawer MK: Prostate-specific antigen. Acta Oncol 30:161-168, 1991
20. Schlimok G, Funke I, Holzmann B, et al: Micrometastatic cancer cells in bone marrow: In vitro detection with anti-cytokeratin and in vivo labeling with anti-17-1A monoclonal antibodies. Proc Natl Acad Sci USA 84:8672-8676, 1987
21. Debus E, Weber K, Osborn M: Monoclonal cytokeratin antibodies that distinguish simple from stratified squamous epithelia. EMBO J 1:1641-1647, 1982
22. Gallee MPW, van Vroonhoven CCJ, van der Korput HAGM, et al: Characterization of monoclonal antibodies raised against prostatic cell line PC-82. Prostate 9:33-45, 1986
23. Chomczynski P, Sacchi N: Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159, 1987
24. Schulz P, Stuck R, Feldmann H: Sequence of a cDNA clone encompassing the complete mature human prostate specific antigen (PSA) and an unspliced leader sequence. Nucleic Acids Res 16:6226, 1988
25. Israeli RS, Powell CT, Fair WR, et al: Molecular cloning of a cDNA encoding a prostate-specific membrane antigen. Cancer Res 53:227-230, 1993
26. Riegman PHJ, Klaassen P, van der Korput JAGM, et al: Molecular cloning and characterization of novel prostate antigen cDNAs. Biochem Biophys Res Commun 155:181-188, 1988
27. Shuldiner AR, Nivula A, Roth J: RNA-template specific PCR: A novel strategy to reduce dramatically false positives. Genes 91:139-142, 1990
28. Heston WDW: Detection of hematogenous dissemination of prostatic cancer by RT-PCR with primers specific for prostate-specific membrane antigen. Clin Chem 41:1687-1688, 1995
29. Riesenberg R, Oberneder R, Kriegmair M, et al: Immunocytochemical double staining of cytokeratin and prostate specific antigen in individual prostatic tumor cells. Histochem J 99:61-66, 1993
30. Yu H, Diamandis EP, Sutherland DJA: Immunoreactive prostate-specific antigen levels in female and male breast tumors and its association with steroid hormone receptors and patient age. Clin Biochem 27:75-79, 1994
31. Foretova L, Garber JE, Sadowsky NI, et al: Prostate-specific antigen in nipple aspirate. Lancet 347:1631, 1996
32. Monne M, Croce CM, Yu H, et al: Molecular characterization of prostate-specific antigen messenger RNA expressed in breast tumors. Cancer Res 54:6344-6347, 1994
33. Liotta LA, Kleinerman J, Saidel GM: Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation. Cancer Res 34:997-1004, 1974
34. Chelly J, Concordet J-P, Kaplan J-C, et al: Illegitimate transcription: Transcription of any gene in any cell type. Proc Natl Acad Sci USA 86:2617-2621, 1989
35. Pantel K, Schlimok G, Angstwurm M, et al: Methodological analysis of immunocytochemical screening for disseminated epithelial tumor cells in bone marrow. J Hematother 3:165-173, 1994
36. Schoenfeld A, Luqmani Y, Smith D, et al: Detection of breast cancer micrometastases in axillary lymph nodes by using polymerase chain reaction. Cancer Res 54:2986-2990, 1994
37. Krismann M, Todt B, Schröder J, et al: Low specificity of cytokeratin 19 reverse transcriptase-polymerase chain reaction analyses for detection of hematogenous lung cancer dissemination. J Clin Oncol 13:2769-2775, 1995
38. Pantel K, Schlimok G, Braun S, et al: Differential expression of proliferation-associated molecules in individual micrometastatic carcinoma cells. J Natl Cancer Inst 85:1419-1424, 1993