Mitotic arrest and anaphase aberrations induced by vinorelbine in hamster cells in vitro

Anti-Cancer Drugs

Volumn 8, Issue 5, 1997, Pages 529-532

  González Cid, Marcela ^a   Cuello, María Teresa ^a   Larripa, Irene ^a  

^a INST DE INVEST HEMATOLOGICAS   (Argentina)

Author keywords

Abnormal anaphase telophase cells; Aneugenic effect; Spindle poison; Vinorelbine

Indexed keywords

NAVELBINE;

ANAPHASE; ANEUPLOIDY; ANIMAL CELL; ARTICLE; CHO CELL; CYTOPATHOGENIC EFFECT; DOSE RESPONSE; DRUG EFFECT; DRUG MEGADOSE; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; SISTER CHROMATID EXCHANGE;

ANAPHASE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL CYCLE; CELL DIVISION; CHO CELLS; CRICETINAE; KINETICS; MITOSIS; SISTER CHROMATID EXCHANGE; TELOPHASE; VINBLASTINE;

EID: 0030845037     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-199706000-00017     Document Type: Article

References (24)

1. Calabresi P, Parks RE. Quimioterapia de las enfermedades neoplásicas. In: Goodman Gilman A, Goodman LS, Rall TW, Murad F, eds. Las bases farmacolögicas de la terapéutica. México: Editorial Médica Panamericana 1986: 1214-7.
2. ® prototype of a new series of vinblastine derivatives. Semin Oncol 1989; 16: 2-4.
3. ®. Semin Oncol 1989; 16: 21-5.
4. ®. Semin Oncol 1989; 16: 15-20.
5. ®. Introduction. Semin Oncol 1989; 16: 1.
6. Burris HA, Fields S. Summary of data from in vitro and phase I Vinorelbine (Navelbine) studies. Semin Oncol 1994; 21: 14-20.
7. ® in phase I-II clinical studies. Semin Oncol 1989; 16: 37-40.
8. Lobert S, Vulevic B, Corrcia JJ. Interaction of Vinca alkaloids with tubulin: a comparison of vinblastine, vincristine, and vinorelbine. Biochemistry 1996; 35: 6806-14.
9. Perry P, Wolff S. New Giemsa method for the differential staining of sister chromatids. Nature 1974; 251: 156-8.
10. Schneider EL, Nakanishi Y, Lewis J, Sternberg H. Simultaneous examination of sister chromatid exchanges and cell replication kinetics in tumor and normal cells in vivo. Cancer Res 1981; 41: 4973-5.
11. Miller BM, Adler ID. Suspect spindle poisons: analysis of c-mitotic effects in mouse bone. Mutagenesis 1989; 4: 208-15.
12. Perry PE, Thomson EJ. The methodology of sister chromatid exchanges. In: Kilbey BJ, Legator M, Nichols W, Ramel C, eds. Handbook of mutagenicity test procedures. Amsterdam: Elsevier 1984: 495-529.
13. Morgan WF, Crossen PE. Mitotic spindle inhibitors and sister-chromatid exchange in human chromosomes. Mutat Res 1980; 77: 283-6.
14. Banerjee A, Benedict WF. Production of sister chromatid exchanges by various cancer chemotherapeutic agents. Cancer Res 1979; 39: 797-9.
15. Stoll C, Borgaonkar DS, Levy JM. Effect of vincristine on sister chromatid exchanges of normal human lymphocytes. Cancer Res 1976; 36: 2710-3.
16. Jordan MA, Thrower D, Wilson L. Mechanism of inhibition of cell proliferation by Vinca alkaloids. Cancer Res 1991; 51: 2212-22.
17. Pauwels O, Kiss R, Pasteels JL, Atassi G. Cytotoxicity, cell cycle kinetics and morphonuclear-induced effects of Vinca alkaloid anticancer agents. J Pharm Pharmacol 1995; 47: 870-5.
18. Pacchierotti F, Bassani B, Leopardi P, Zijno A. Origin of aneuploidy in relation to disturbances of cell-cycle progression. II: Cytogenetic analysis of various parameters in mouse bone marrow cells after colchicine or hydroquinone treatment. Mutagenesis 1991; 6: 307-11.
19. Adler ID, Kliesch U, van Hummelen P, Kirsch-Volders M. Mouse micronucleus tests with known and suspect spindle poisons: results from two laboratories. Mutagenesis 1991; 6: 47-53.
20. Dulout FN, Olivero OA. Anaphase-telophase analysis of chromosomal damage induced by chemicals. Environ Mutagen 1984; 6: 299-310.
21. Hsu TC, Liang JC, Shirley LR. Aneuploidy induction by mitotic arrestants. Effects of diazepam on diploid Chinese hamster cells. Mutat Res 1983; 122: 201-9.
22. Tucker RW, Owellen RJ, Harris SB. Correlation of cytotoxicity and mitotic spindle dissolution by vinblastine in mammalian cells. Cancer Res 1977; 37: 4346-51.
23. Bogajewski J. The anaphase test. Mutat Res 1984; 130: 189.
24. George P, Journey LJ, Goldstein MN. Effect of vincristine on the tine structure of HeLa cells during mitosis. J Natl Cancer Inst 1965; 35: 355-75.