Effects of CP-060S on membrane channels in vascular smooth muscle cells from guinea pig

European Journal of Pharmacology

Volumn 330, Issue 1, 1997, Pages 93-99

  Ohya, Yusuke ^a   Adachi, Natsuko ^a   Setoguchi, Motoko ^a   Abe, Isao ^a   Fujishima, Masatoshi ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Ca2+ channel; Ca2+ channel antagonist; CP 060S; Electrophysiology; Smooth muscle; vascular; Voltage clamp

Indexed keywords

2 (3,5 DI TERT BUTYL 4 HYDROXYPHENYL) 3 [3 [N METHYL N [2 (3,4 METHYLENEDIOXYPHENOXY)ETHYL]AMINO]PROPYL] 4 THIAZOLIDINONE; 2 [3,5 BIS(1,1 DIMETHYLETHYL) 4 HYDROXYPHENYL] 3 [3 [N METHYL N [2 (3,4 METHYLENEDIOXYPHENOXY) ETHYL] AMINO] PROPYL] 1,3 THIAZOLIDIN 4 ONE HYDROGEN; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; DILTIAZEM; GALLOPAMIL; NIFEDIPINE; POTASSIUM CHANNEL; SODIUM CHANNEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; FEMALE; GUINEA PIG; MEMBRANE CHANNEL; MESENTERIC ARTERY; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; VASCULAR SMOOTH MUSCLE;

ANIMALS; CALCIUM CHANNELS; FEMALE; GUINEA PIGS; ION CHANNELS; MEMBRANE POTENTIALS; MESENTERIC ARTERIES; MUSCLE, SMOOTH, VASCULAR; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; SODIUM CHANNELS; THIAZOLES; THIAZOLIDINES;

EID: 0030844608     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)00173-8     Document Type: Article

References (16)

1. Bean, B.P., 1984. Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state. Proc. Natl. Acad. Sci. USA 81, 6388-6392.
2. Bustamane, J.O., 1985. Block of sodium currents by the calcium antagonist D600 in human heart cell segments. Pflüg. Arch. 403, 225-227.
3. Fleckenstein, A., 1983. History of calcium antagonists. Circ. Res. 52 (I 3-1), 16.
4. + channels. J. Pharmacol. Exp. Ther. 234, 134-140.
5. Koga, T., Akima, M., Tamura, K., Suzuki, Y., Kato, T., Nabata, H., 1996. The inhibitory effects of CP-060S on ischemia- and reperfusion-induced arrhythmias in anesthetized rats. Jpn. J. Pharmacol. 71 (Suppl. I), 321p.
6. 2+ channels in rat aorta smooth muscle cells in primary culture. Circ. Res. 67, 469-480.
7. Lee, K.S., Tsien, R.W., 1983. Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialyzed heart cells. Nature 302, 790-794.
8. Ohya, Y., Sperelakis, N., 1989a. ATP regulation of the slow calcium channels in vascular smooth muscle cells of guinea pig mesenteric artery. Circ. Res. 64, 145-154.
9. Ohya, Y., Sperelakis, N., 1989b. Fast Na and slow Ca channels in single uterine muscle cells from pregnant rats. Am. J. Physiol. 257, C408-C412.
10. Ohya, Y., Sperelakis, N., 1991. Involvement of a GTP-binding protein in stimulating action of angiotensin-II on calcium channels in vascular smooth muscle. Circ. Res. 68, 763-777.
11. 2+ channels in resistance arteries from spontaneously hypertensive rats. Circ. Res. 73, 703-710.
12. Okabe, K., Terada, K., Kitamura, K., Kuriyama, H., 1987. Selective and long-lasting inhibitory actions of the dihydropyridine derivative, CV-4093, on calcium currents in smooth muscle cells of the rabbit pulmonary artery. J. Pharmacol. Exp. Ther. 243, 378-383.
13. 1-selective adrenoceptor antagonist, on voltage-dependent calcium channels in guinea-pig artery and vein. Br. J. Pharmacol. 115, 198-202.
14. 2+ overload in cardiomyocytes and mechanical activities in vascular strips. Eur. J. Pharmacol. 312, 195-202.
15. 2+ channels in the smooth muscle cell membrane of rabbit small intestine. Pflüg. Arch. 408, 552-557.
16. 2+ antagonists in the smooth muscle cell membrane of rabbit small intestine. Pflüg. Arch. 408, 558-564.