The role of a-melanocyte-stimulating hormone in cutaneous biology

Journal of Investigative Dermatology Symposium Proceedings

Volumn 2, Issue 1, 1997, Pages 87-93

  Lugcr, Thomas A ^a   Scholzen, Thomas ^a   Grabbe, Stephan ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Ittflamtnationlneuropep ; Tidelneuroimmunomodulationlepidermis

Indexed keywords

ALPHA INTERMEDIN;

CELL PROLIFERATION; CONFERENCE PAPER; DOWN REGULATION; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOMODULATION; KERATINOCYTE; MELANOCYTE; SKIN INFLAMMATION;

EID: 0030843370     PISSN: 10870024     EISSN: None     Source Type: Journal    
DOI: 10.1038/jidsymp.1997.17     Document Type: Article

References (90)

1. Aebischer I, Stämpfli MR, Zürcher A, Miescher S, Unvyler A, Frey B, Luger TA, White RR, Stadier DM: Neuropeptides are potent modulators of human in vitro immunoglobulin E s>-nthesis. EtirJ Immunol 24:1903-1913, 1994
2. Aebischer I, Stämpfli M, Micsciicr S, Hon M, Zürcher AW, Stadier BM: Neuropeptides accentuate interleukin-4 induced human immunoglobulin E synthesis in vitro. Exp Dcrmatol 4:418-423, 1995
3. Armstrong CA, Anscl JC, Luger TA: Melanocytic cell cytokincs. In: Luger TA, Schwarz T (eds.). Epidermal Growth Factors and Cytokines. Marcel Dekker, Inc. New York, 1994, pp 433-450
4. Autelitano DJ, Blum M, Lopingco M, Allen RG, Roberts JL: Corticotropin-releasing factor differentially regulates anterior and intermediate pituitary lobe proopiomelanocortin gene transcripdon, nuclear precursor RNA and mature mRNA m vivo. NciirocndocTitiology 51:123-130, 1990
5. Autelitano DJ, Lundblad JR, Blum M, Roberts JL: Hormonal regulation of POMC gene expression. Anna Ret' Physio! 51:715-726, 1989
6. Benjannet S, Rondeau N, Day R, Chrétien M, Seidah NG: PCI and.PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues. Proc Natl Acad SciUSA 88:3564-3568, 1991
7. Bhardwaj RS, Becher E, Mahnke K, Hartmeyer M, Schwarz T. Scholzen T, Luger TA: Evidence for the differential expression of the functional alpha melanocyte stimulating hormone receptor MC-1 on human monocytes.J Immunol 158:33783384, 1997
8. Bhardwaj RS, Luger TA: Proopiomelanocortin production by epidermal cells: evidence for an immune neuro-endocrine network in the epidermis. Arch Dermatol Res 287:85-90, 1994
9. Bhardwaj RS, Schwarz A, Becher E, Mahnke K, Riemann H, Aragane Y, Schwarz T, Luger TA: Pro-opîomelanocortïn-derived peptides induce IL-10 production in human monocytes. J Immimol 156:2517-2521, 1996
10. Blalock JE: The syntax of immune-ncuroendocrine communication. Immunol Today 15:504-511, 1994
11. Boston BA, Cone RD: Characterization of melanocortin receptor subtype expression in murine adipose tissues and in the 3T3-L1 cell line. Endocrinology 137:20432050, 1996
12. Burbach JPH, Wiegant VM: Gene expression, biosynthesis and processing of proopiomelanocortin peptides and vasopressin. In: de Wied D (ed.). Nenropcptide$;Ba$ics and Perspectives. Elsevicr, Amsterdam, 1990, pp 45-103
13. Cannon JG, Tatro JB, Reichlin S, Dinarello CA: Alpha melanocyte stimulating hormone inhibits immunostimulatory and inflammatory actions of interleukin 1. J Immunol 137:2232-2236, 1986
14. Catania A, Airaghi L, Manfredi MG, Vivirito MC, Milazzo F, Lipton JM, Zanussi C: Proopiomelanocortin-derived peptides and cytokiiics: relations in patients with acquired immunodeficiency syndrome. Clin Immunol Immnnopathol 66:73-79, 1993
15. Catania A, Gcrloni V, Procaccia S, Airaghi L, Manfredi MG, Lomater C, Grossi L, Lipton JM: The anticytokine neuropeptide alpha-melanocyte-stimularing hormone in synovial fluid of patients with rheumatic diseases: comparisons with other anticytokine molecules. Keuroimmunomodulation 1:321-328, 1994a
16. Catania A, Lipton JM: Alpha-melanocyte stimulating hormone in the modulation of host reactions. Endocr Rev 14:564-576, 1993
17. Catania A, Manfredi MG, Airaglu L, Vivirito MC, Capetti A, Milazzo F, Lipton JM, Zanussi C: Plasma concentration of eytokinc antagonists in patients with HIV infection. Xeiiroimmunomoditlation 1:42-49, 1994b
18. Ceriani G, Diaz J, Murphree S, Catania A, Lipton JM: The neuropeptide alphanielanocyte-stimulating hormone inhibits experimental arthritis in rats. AVuromiininwnwdiilathii 1:28-32, 1994
19. Chakraborty AK, Orlow SJ, Pawelek JM: Stimulation of the receptor for melanocytestimulating hormone by retinoîc acid. FEBS Lett 276:205-208, 1990
20. Chakraborty A, Pawelek J: MSH receptors in immortalized human epidermal keratinocytes: a potential mechanism for coordinate regulation of the epidermalmelanin unit.J Cell PhyshI 157:344-350, 1993
21. Chakraborty A, Slominski A, Ermak G, Hwang J, Pawelek J: Ultraviolet B and melanocyte-stimulating hormone (MSH) stimulate mRNA production for alpha MSH receptors and proopiomelanocortin-derived peptides in mouse melanoma cells and transformed keratinocytcs. J Invest Dcrmatol 105:655-659, 1995
22. Chhajlani V, Muceniece R, Wikberg JE: Molecular cloning of a novel human melanocortin receptor. Biochem Biophys Res Commun 195:866-873, 1993
23. Chhajlani V, Wikberg JE: Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA. FEES Lett 309:417-420, 1992
24. Chiao H, Foster S, Thomas R, Lipton J, Star RA: Alpha-melanocyte-stimularing hormone reduces endotoxin-induced liver inflammation. J Clin Invest 97:2038 -2044, 1996
25. Cone RD, Lu D, Koppula S, Vage DI, Klungland H, Boston B, Chen W, Orth DN, Pouton C, Kesterson RA: The melanocortin receptors: agonists, antagonists, and the hormonal control of pigmentation. Recent Prog Honn Res 51:287-317, 1996
26. Cone RD, Mountjoy KG: Cloning and functional characterization of human adrenocorticotropin receptor. In: Capponi A, Chambaz EM, Mantero F (eds): Cellular and Molecular Biologf of the Adrenal Cortex. ). Libbey Eurotext, Paris, 1992, pp 27-40
27. De Luca M, Siegrist W, Bondanza S, Mathor M, Cancedda R, Ebcrle AN: Alpha melanocyte stimulating hormone (alpha MSH) stimulates normal human melanocyte growth by binding to high-affinity receptors. J Cell Set 105:1079-1084, 1993
28. Duvaux Miret O, Stefano GB, Smith EM, Dissous C, Capron A: Immunosuppression in the definitive and intermediate hosts of the human parasite Schistosoma tnansoni by release of immunoactive neuropeptides. Prof Hall Acad SciUSA 89:778-781, 1992
29. Eberle AN: Tlie Melanotropins. Karger, Basel, 1988
30. Eberle AN, Siegrist W, Bagutti C, Chluba De TapiaJ, Solca F, Wikberg JE, Chhajlani V: Receptors for melanocyte-stimuladng hormone on melanoma cells. Ann NY Acad Sa 680:320-341, 1993
31. Eller MS, Ostrom K, Gilchrcst BA: DNA damage enhances melanogenesis. Proc Natl Acad SciUSA 93:1087-1092, 1996
32. Englaro W, Rezzonico R, Durand Clement M, Lallemand D, Ortonne JP, Ballotti R: Mitogen-activated protein kinasë pathway and AP-1 are activated during cAMPinduced melanogenesis in B-16 melanoma cells. J Biol Chem 270:24315-24320, 1995
33. Ermak G, Slominski A: Production of POMC, CRH-R1, MCI- and MC2-receptor mRNA and expression of tyrosinase gene in relation to hair cycle and dexamethasone treatment in C57BL/6 mouse skin. J Infest Dcrmatol 108:160-165, 1997
34. Fan W, Boston BA, Kesterson RA, Hruby VJ, Cone RD: Role of melanocholinergic neurons in feeding and the obesity syndrome. Nature 385:165-168, 1997
35. Farooqiii JZ, Medrano EE, Abdel Malek Z, Nordlund J: The expression of proopiomelanocortin and various POMC-derived peptides in mouse and human skin. Ann NY Acad Sci680:508-510, 1993
36. Farooqui JZ, Medrano EE, Boissy RE, Tigelaar RE, Nordlund JJ: Thy-l + dendritic cells express truncated form of POMC mRNA. Exp Dermatol 4:297-301, 1995
37. Gantz I, Konda Y, Tashiro T, Shimoto Y, Miwa H, Munzert G, Watson SJ, DelValle J, Yamada T: Molecular cloning of a novel melanocortin receptor. J Biol Chem 268:8246-8250, 1993a
38. Gantz I, Miwa H, Konda Y, Shimoto Y, Tashiro T, Watson SJ, DelValle J, Yamada T: Molecular cloning, expression, and gene localization of a fourth melanocortin receptor. J Biol Chem 268:15174-15179, 1993b
39. Gantz I, Shimoto Y, Konda Y, Miwa H, Dickinson CJ, Yamada T: Molecular cloning, expression, and characterization of a fifth melanocortin receptor. Biochem Biophys Res Commun 200:1214-1220, 1994
40. Gantz I, Tashiro T, Barcroft C, Konda Y, Shimoto Y, Miwa H, Glover T, Munzert G, Yamada T: Localization of the genes encoding the melanocortin-2 (adrenocorticotropic hormone) and melanocortin-3 receptors to chromosomes 18pll.2 and 20ql3.2-ql3.3 by fluorescence in situ hybridization. Cenomics 18:166-167, 1993c
41. Glinski W, Brodecfca H, Glinska-Ferenz M, Kowalski D: Increased concentration of beta-endorphin in the sera of patients with severe atopic dermatitis. Acta Derm Venereal 75:9-11, 1995
42. Grabbe S, Bhardwaj RS, Steinen M, Mahnke K, Simon MM, Schwarz T, Luger TA: Alpha-melanocyte stimulating hormone induces hapten-specific tolerance in mice.Jimmunol 156:473-478, 1996
43. Halaban R, Pomerantz SH, Marshall S, Lambert DT, Lemer AB: Regulation of tyrosinase in human melanocytes grown in culture., / Cell Biol 97:480-488, 1983
44. Hartmeyer M, Schclzen T, Becher E, Bhardwaj RS, Fastrich M, Schwarz T, Lugcr TA: Human microvascular endothelial cells (HMEC-1) express the melanocortin receptor type 1 and produce increased levels of IL-8 upon stimulation with aMSH. J Immunol 159: in press, 1997
45. Herlyn M, Mancianti ML, Jambrosic J, Bolen JB, Koprowski H: Regulatory factors diat determine growtii and phenotype of normal human melanocytes. Exp Cell Res 179:322-331, 1988
46. Hirobe T: Control of melanocyte proliferation and differentiation in the mouse epidermis. Pigment Cell Res 5:1-11, 1992
47. Holzmann A, Altmeyer P, Stohr L, Chilf GN: Beeinflussung des Alpha-MSH durch UVA-Bestrahlung der Haut-ein Funktionstest. Hautarzt 34:294-297, 1983
48. Hunt G, Donatien PD, Cresswell JE, Thody AJ: The effect of alpha-MSH on the attachment of human melanocytes to laminin and fibronectin. Evidence for specific alpha-MSH receptors on these cells. Ann NY Acad Sci680:549-551, 1993
49. Hunt G, Thody AJ: Agouti protein can act independently of melanocyte-stimulating hormone to inhibit melanogenesis. J Enâocrinol 147:R1-R4, 1995
50. Huszar D, Lynch CA, Fairchild-Huntress V, Dunmore JH, Fang Q, Berkerneier LR, Gu W, Kesterson RA, Boston BA, Cone RD, Smith FJ, Campfield MA, Burn P, Lee F: Targeted disruption of die melanocortin-4 receptor results in obesity in mice. Cell 68:131-141, 1997
51. JiangJ, Sharma SD, Hruby VJ, FinkJL, Hadley ME: Human epidermal melanocyte and keratinocyte mclanotropin receptors: visualization by melanotropic peptide conjugated macrospheres (polyamide beads). Exp Dermatol 5:325-333, 1996
52. Kiss M, Wlaschek M, Brenneisen P, Michel G, Hommel C, Lange TS, Peus D,
53. Kemeny L, Dobozy A, Scharffetter Kochanck K, Ruzicka T: Alpha-melanocyte stimulating hormone induces coll age nasc/matrix metalloproteinase-1 in human dermal fibroblasts. Biol Client Hoppe Seyler 376:425-430, 1995
54. Köck A, Schauer E, Schwarz T, Luger TA: Human keratinocytcs synthesize and release neuropeptides such as er-MSH and ACTH. In; Mcltzer M, Mantovani A (eds.). Cellular and Cytokine Networks in Tissue Immunity. John Wiley &: Sons, Inc. New York, 1991, pp 105-110
55. Lamacz M, Tonon MC, Louïset E, Cazïn L, Vaudry H: The intermediate lobe of the pituitary, model of neurocndocrine communication. Arch Int Physiol Biochim 99:205-219, 1991
56. Lipton JM, Catania A: Antiinflammatory actions of the neuroimmunomodulator a-MSH. Immunol Today 18:140-145. 1997
57. Lipton JM, Ceriani GT Macaluso A, McCoy D, Garnes K, Biltz J, Catania A: Andinflammatory effects of the neuropeptide alpha-MSH in acute, chronic, and systemic inflammation. Ann NY Acad Sci741:137-148, 1994
58. Lu D, Willard D, Patel IR, Kadwell S. Overton L, Kost T, Luther M, Chen W, Woychik RP, Wilkison WO, Cone RD: Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor. Nature 371:799-802, 1994
59. Luger TA, Schauer E, Trautinger F, Krutmann J, Ansei J, Schwarz A, Schwarz T: Production of immunosuppressing melanotropins by kcratînocytes. Ann NY Acad Sci680:567-570, 1993
60. Lunec J, Pieron C, Sherbet GV, Thody AJ: Alpha-melanocyte-stimulating hormone immunorcacrivity in melanoma cells. Pathobfology 58:193-197, -1990
61. Lyons PD, Blalock JE: The kinetics of ACTH.expression in rat leukocyte subpopulations. J Keuroimmimol 63:103-112, 1995
62. Morhenn VB: The physiology of scratching: involvement of proopiomelanocortin gene-coded proteins in Langerhans cells. Prog Neiiro Endo Immun 4:265-267, 1991
63. Mountjoy KG, Mortrud MT, Low MJ, Simcrly RB, Cone RD: Localization of the mcIanocortin-4 receptor (MC4-R) in neuroendocrine and autonomie control circuits in the brain. Mol Endocnnol 8:1298-1308, 1994
64. Mountjoy KG, Robbîns LS, Mortrud MT, Cone PvD: The cloning of a family of genes that encode the melanocortin receptors. Science 257:1248-1251, 1992
65. Oka M, Icliihaslii M, Chakraborty AK: Enhanced expression of protein kinase C subspecies in melanogcnic compartments in B16 melanoma cells by UVB or MSH [letter]. J Invest Dennatol 106:377-378. 1996
66. Orel L, Simon MM, Karlseder J, Bhardwaj RS, Trautinger F, Schwarz T, Luger TA: Alpha-melanocyte stimulating hormone downregulates differentiation driven heat shock protein 70 expression in keratinocytes. J Invest Dcrmatol 108:401-405, 1997
67. Park HY, Gilchrest BA: Protein kinase C: biochemical characteristics and role in melanocyte biology. J Dennatol Set 6:185-193, 1993
68. Pawelek JM: Studies on the Cloudman melanoma cell line as a model for the action of MSH. YaleJ Biol Met 58:571-578, 1985
69. Rajora N, Ceriani G, Catania A, Star RA, Murphy MT, Lipton JM: alpha-MSH production, receptors, and influence on neopterin în a human monocyte/ macrophage cell line. J Leiikoe Biol 59:248-253, 1996
70. RJheins LA, Cotleur AL, Kleier RS, Hoppenjans WB, Sauder DN, Nordlund JJ: Alpha-melanocyte stimulating hormone modulates contact hypersensïtîvity responsiveness in C57/BL6 mice.J Invest Dennatol 93:511-517, 1989
71. Robbins LS, Nadeau JH, Johnson KR, Kelly MA, Roselli Rehfuss L, Baack E, Mountjoy KG, Cone RD: Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function. Cell 72:827-834. 1993
72. Schauer E, Trautinger F, Köck A, Bhardwaj RS, Simon M, Schwarz A, Ansei JC, Schwarz T, Luger TA: Proopiomelanocortin derived peptides are synthesized and released by human keratinocytes. J Clin Invest 93:2258-2262, 1994 Schwartze G, Fiedler H: Zur diagnostischen Bedeutung des α-MSH beim malignen Melanom des Menschen. Hautarzt 45:468-470, 1994
73. Seidah NG, Day R, Benjannet S, Rondeau N, Boudreault A, Reudelhubcr T, Schafer MK, Watson SJ, Chrétien M: The prohormone and proprotein processing enzymes PCI and PC2: structure, selective cleavage of mouse POMC and human renin at pairs of basic residues, cellular expression, tissue distribution, and mRNA regulation. NIDA Res Monogr 126:132-150, 1992
74. Siegrist W, Stutz S, Eberle AN: Homologous and heterologous regulation of alpha-melanocytc-stimulating hormone receptors in human and mouse melanoma cell lines. Cancer Res 54:2604-2610, 1994
75. Slominski A: POMC gene expression in mouse and hamster melanoma cells. FEBS Lett 291:165-168, 1991
76. Slominski A, Ermak G, Hwang J, Mazurkiewicz J, Corliss D, Eastman A: The expression of proopiomelanocortin (POMC) and of corticotropin releasing hormone receptor (CRH-R) genes in mouse skin. Biochim Biophys Acta 1289: 247-251, 1996
77. Slominski A, Paus R, Mazurkiewicz J: Proopiomelanocortin expression in the skin during induced hair growth in mice. Experientia 48:50-54, 1992
78. Slominski A, Paus R, Wortsman J: On the potential role of proopiomelanocortin in skin physiology and pathology. Mol Cell Endocrinol 93:C1-C6, 1993a
79. Slominski A, Wortsman J, Mazurkiewicz JE, Matsuoka L, Dietrich J, Lawrence K, Gorbani A, Paus R: Detection of proopiomelanocortin-derived antigens in normal and pathologic human skin. J Lab Clin Med 122:658-666, 1993b
80. Smith AI, Funder JW: Proopiomelanocortin processing in the pituitary, central nervous system, and peripheral tissues. Endocr Rev 9:159-179, 1988
81. Spiro J, Parker S, Oliver I, Fraser C, Marks JM, Thody AJ: Effect of PUVA on plasma and skin immunoreactive alpha-melanocyte stimulating hormone concentrations. BrJ Dennatol 117:703-707, 1987
82. Star RA, Rajora N, HuangJ, Chavez R, Catania A, Lipton JM: Evidence of autocrine modulation of macrophage nitric oxide s yn t ha se by alplia-MSH. Prof Natl Acad Sa USA 92:8016-8020, 1995
83. Stricter RM, Polverini PJ, Arenberg DA, Kunkel SL: The role of CXC chemokines äs regulators of angiogcnesis. Shock 4:155-160, 1995a
84. Stricter RM, Polverini PJ, Arenberg DA, Walz A, Opdenakker G, Van Damme J, Kunkel SL: Role of C-X-C chemokines as regulators of angiogenesis in lung cancer. J Lenkoc Biol 57:752-762, 1995b
85. Suzuki I, Cone RD, Im S, Nordlund J, Abdel Malek ZA: Binding of mclanotropic hormones to the melanocortin receptor MC1R on human melanocytes stimulates proliferation and melanogenesis. Endocrinology 137:1627-1633, 1996 Taylor AW, Streïleïn JW, Cousins SW: Alpha-melanocyte-stimulating hormone
86. suppresses antigen-stimulated T cell production of gamma-interferon. Nfuroimmunomodulaion 1:188-194, 1994
87. Teofoli P, Motoki K, Lotti TM, Uitto J, Mauviel A: Proopiomclanocortin (POMC) gene expression by normal skin and keloid fibroblasts in culture: modulation by cytokines. Exp Dematal 6:111-115, 1997
88. Thody AJ, PJdley K, Penny RJ, Chalmers R, Fisher C, Shuster S: MSH peptides are present in mammalian skin. Peptides 4:813-816, 1983
89. Tonon MC, Desrues L, Lamacz M, Charnel N, Jenks B, Vaudry H: Multihormonal regulation of pituitary melanotrophs. Ann NY Acad Sci680:175-187, 1993
90. Wintzen M, Gilchrest BA: Proopiomelanocorrin, its derived peprides, and the skin. J Invest Dermatol 106:3-10, 1996