Cysteine protease CPP32, but not Ich1-L, is expressed in germinal center B cells and their neoplastic counterparts

Human Pathology

Volumn 28, Issue 8, 1997, Pages 912-921

  Xerri, Luc ^a   Devilard, Elisabeth ^b   Ayello, Corinne ^b   Brousset, Pierre ^b   Reed, John C ^b   Emile, Jean François ^b   Hassoun, Jacques ^b   Parmentier, Sophie ^b   Birg, Françoise ^b  

^a INSTITUT PAOLI CALMETTES   (France)

^b NONE

Author keywords

Apoptosis; CPP92; Hodgkin's disease; Ich 1L; Immunohistochemistry; Non Hodgkin's lymphoma

Indexed keywords

CYSTEINE PROTEINASE; CYSTEINE PROTEINASE CPP 32; CYSTEINE PROTEINASE ICH 1 L; UNCLASSIFIED DRUG;

ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; GERMINAL CENTER; HODGKIN DISEASE; HUMAN; HUMAN TISSUE; IMMUNOBLAST; IMMUNOHISTOCHEMISTRY; LYMPHOID ORGAN; MAJOR CLINICAL STUDY; NONHODGKIN LYMPHOMA; PLASMA CELL; PROTEIN EXPRESSION; REED STERNBERG CELL;

EID: 0030843291     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0046-8177(97)90006-X     Document Type: Article

References (44)

1. Martin SJ, Green DR: Protease activation during apoptosis: Death by a thousand cuts? Cell 82:349-352,1995
2. Whyte M: ICE/CED-3 proteases in apoptosis. Trends Cell Biol 6:245-247, 1996
3. Henkart PA: ICE family proteases: Mediators of all apoptotic cell death? Immunity 4:195-201, 1996
4. Ellis RE, Yuan J, Horvitz HR: Mechanisms and function of cell death. Ann Rev Cell Biol 7:663-698, 1991
5. Elis HM, Horvitz HR: Genetic control of programmed cell death in the nematod Caenorhabditis elegans. Cell 44:817-829, 1986
6. Yuan J, Horvitz HR: Genetic mosaic analysis of ced-3 and ced-4, two genes that control programmed cell death in the nematode C. elegans. Dev Biol 138:33-41, 1990
7. Yuan J, Shaham S, Ledoux S, et al: The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell 75:641-752, 1993
8. Cerretti DP, Koslosky CJ, Mosley B, et al: Molecular cloning of the interleukin-1β-converting enzyme. Science 256:97-100, 1995
9. Thornberry NA, Bull HG, Calaycay JR, et al: A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes. Nature 356:768-774, 1992
10. Wang L, Miura M, Bergeron L, et al: Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell 78:739-750, 1994
11. Fernandes-Alnemri T, Litwach G, Alnemri ES: CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1β-converting enzyme. J Biol Chem 269:30761-30764, 1994
12. Kamens J, Paskind M, Hugunin M. et al: Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases. J Biol Chem 270:15250-15256, 1995
13. Fernandes-Alnemri T, Litwack G, Alnemri ES: Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family. Cancer Res 55:2737-2742, 1995
14. Faucheu C, Diu A, Chan AW, et al: A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells. EMBO J 14:1914-1922, 1995
15. Miura M, Zhu H, Rotello R, et al: Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell 75:653-660, 1993
16. Schwartz SM, Bennett MR: Death by any other name. Am J Pathol 147:229-234, 1995
17. Brancolini C, Benedetti M, Schneider C: Microfilament reorganization during apoptosis: The role of Gas2, a possible substrate for ICE-like proteases. EMBO J 14:5179-5190, 1995
18. Neamati N, Fernandez A, Wright S, et al: Degradation of lamin BI precedes oligonucleosomal DNA fragmentation in apoptotic thymocytes and isolated thymocyte nuclei. J Immunol 154:3788-3795, 1995
19. Kaufmann SH, Desnoyers S, Ottaviano Y, et al: Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis. Cancer Res 53:3976-3985, 1993
20. Lazebnik YA, Kaufmann SH, Desnoyers S, et al: Cleavage of poly (ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 371:346-347, 1994
21. Tewari M, Quan LT, O'Rourke K, et al: Yama/CPP32b, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly (ADP-ribose) polymerase. Cell 81:801-809, 1995
22. Gu Y, Sarnecki C, Aldape RA, et al: Cleavage of poly(ADP-ribose) polymerase by interleukin-1 beta converting enzyme and its homologs TX and Nedd-2. J Biol Chem 270:18715-18718, 1995
23. Nicholson DW, Ali A, Thornberry NA, et al: Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376:37-43, 1995
24. Enari M, Talanian RV, Wong WW, et al: Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature 380:723-726, 1996
25. Casciola-Rosen L, Nicholson DW, Cong T, et al: Apopain/ CPP32 cleaves proteins that are essential for cellular repair: A fundamental principle of apoptotic death. J Exp Med 183:1957-1964, 1996
26. + T cells from human immunodeficiency virus-infected asymptomatic individuals. J Exp Med 175:331-340, 1992
27. Fisher GH, Rosenberg FJ, Straus SE, et al: Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 81:935-946, 1995
28. Rieux-Laucat F, Le Deist F, Hivroz C, et al: Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 268:1347-1349, 1995
29. Lee Harris N, Jaffe ES, Stein H, et al: A revised europeanamerican classification of lymphoid neoplasms: A proposal from the International Lymphoma Study Group. Blood 84:1361-1392, 1994
30. Mason DY, Cordell JL, Abdulaziz Z, et al: Preparation of peroxidase antiperoxidase (PAP) complexes for immunohistological labeling of monoclonal antibodies. J Histochem Cytochem 30:1114-1122, 1982
31. Cordell JL, Falini B, Erber WN, et al: Immunoenzymatic labelling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP) complexes. J Histochem Cytochem 32:219-229, 1984
32. Falini B, Abdulaziz Z, Gerdes J, et al: Description of a sequential staining procedure for double immunoenzymatic staining of pairs of antigens using monoclonal antibodies. J Immunol Methods 93:265-272, 1986
33. Xerri L, Parc P, Brousset P, et al: Predominant expression of the long isoform of Bcl-x (Bcl-xL) in human lymphomas. Br J Haematol 92:900-906, 1996
34. Brousset P, Benharroch D, Krajewski S, et al: Frequent expression of the cell death-inducing gene Bax in Reed Sternberg cells of Hodgkin's disease. Blood 87:2470-2475, 1996
35. McLennan ICM: Germinal centers. Ann Rev Immunol 12:117-120, 1994
36. Xerri L, Carbuccia N, Parc P, et al: Frequent expression of FAS-APO-1 in Hodgkin's disease and anaplastic large cell lymphomas. Histopathology 104:424-430, 1995
37. Enari M, Hase A, Nagata S: Apoptosis by a cytosolic extract from Fas-activated cells. EMBO J 14:5201-5208, 1995
38. Enari M, Hug H, Nagata S: Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature 375:78-81, 1995
39. Los M, Van de Craen M, Penning LC, et al: Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis. Nature 375:81-83, 1995
40. Li P, Alien H, Banerjee S, et al: Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock. Cell 80:401-411, 1995
41. Kerr JFR, Willye AH, Curie AR: Apoptosis: A basic biologic phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257, 1972
42. Obeid LM, Linardic CM, Karolak LA, et al: Programmed cell death induced by ceramide. Science 259:1767-1771, 1993
43. Martin SJ, Newmeyer DD, Mathias S, et al: Cell-free reconstitution of Fas-, UV radiation- and ceramide-induced apoptosis. EMBO J 14:5191-5200, 1995
44. Krajewski S, Gascoyne RD, Zapata JM, et al: Immunolocalization of the ICE/Ced-3 - family protease, CPP32 (caspase-3), in non-Hodgkin's lymphomas, chronic lymphocytic leukemias, and reactive lymph nodes. Blood 89:3817-3825, 1997.