Normal immunologic response to a neoantigen, bacteriophage ΦX-174, in baboons with long-term lymphohematopoietic reconstitution from highly purified CD34+ Lin- allogeneic marrow cells

Blood

Volumn 90, Issue 4, 1997, Pages 1701-1708

  Andrews, Robert G ^a   Winkler, Aaron ^b   Potter, Jennifer ^b   Bryant, Eileen ^b   Knitter, Glenn H ^b   Bernstein, Irwin D ^b   Ochs, Hans D ^b  

^a Fred Hutchinson Cancer Research Center   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CD34 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; IMMUNOGLOBULIN;

ALLOGENIC BONE MARROW TRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BABOON; BACTERIOPHAGE PHI X 174; BURST FORMING UNIT E; CELL TRANSPLANTATION; CHIMERA; COLONY FORMING CELL; COLONY FORMING UNIT GM; CONTROLLED STUDY; FEMALE; GENE REARRANGEMENT; HEMATOPOIESIS; IMMUNIZATION; IMMUNOGLOBULIN BLOOD LEVEL; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0030843273     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v90.4.1701     Document Type: Article

References (48)

1. Spangrude GJ: Biological and clinical aspects of hematopoietic stem cells. Annu Rev Med 45:39, 1994
2. Bertoncello I, Hodgson GS, Bradley TR: Multiparameter analysis of transplantable stem cells. I. The separation and enrichment of stem cell homing to marrow and spleen on the basis of rhodamine-123 fluorescence. Exp Hematol 13:999, 1985
3. Hodgson GS, Bradley TR: Properties of haematopoietic stem cells surviving 5-fluorouracil treatment: Evidence for a pre-CFU-S cell? Nature 281:381, 1979
4. Berenson RJ, Andrews RG, Bensinger WI, Kalamasz D, Knitter G, Buckner CD, Bernstein ID: CD34+ marrow cells engraft lethally irradiated baboons. J Clin Invest 81:951, 1988
5. + marrow cells, devoid of T and B lymphocytes, reconstitute stable lymphopoiesis and myelopoiesis in lethally irradiated allogeneic baboons. Blood 80:1693, 1992
6. + marrow cells in patients with breast cancer and neuroblastoma. Blood 77:1717, 1991
7. Kamel-Reid S, Dick JE: Engraftment of immune-deficient mice with human hematopoietic stem cells. Science 242:1706, 1988
8. Baum CM, Weissman IL, Tsukamoto AS, Buckle AM, Peault B: Isolation of a candidate human hematopoietic stem-cell population. Proc Natl Acad Sci USA 89:2804, 1992
9. Srour EF, Zanjani ED, Cornetta K, Traycoff CM, Flake AW, Hedrick M, Brandt JE, Leemhuis T, Huffman R: Persistence of human multilineage, self-renewing lymphohematopoietic stem cells in chimeric sheep. Blood 82:3333, 1993
10. Ochs HD, Buckley RH, Kobayashi RH, Kobayashi AL, Sorensen RU, Douglas SD, Hamilton BL. Hershfield MS: Antibody responses to bacteriophage phi X174 in patients with adenosine deaminase deficiency. Blood 80:1163, 1992
11. Ochs HD, Nonoyama S, Zhu Q. Farrington M, Wedgwood RJ: Regulation of antibody responses: The role of complement and adhesion molecules. Clin Immunol Immunopathol 67:S33, 1993
12. Loeffel S, Chang CH, Heyn R, Harada S, Lipscomb H, Sinangil F, Volsky DJ, McClain K, Ochs H, Purtilo DT: Necrotizing lymphoid vasculitis in X-linked lymphoproliferative syndrome. Arch Pathol Lab Med 109:546, 1985
13. Witherspoon RP, Deeg HJ, Lum LG, Ochs HD, Hansen JA, Thomas ED, Storb R: Immunologic recovery in human marrow graft recipients given cyclosporine or methotrexate for the prevention of graft-versus-host disease. Transplantation 37:456, 1984
14. Wilherspoon RP, Storb R, Ochs HD, Fluornoy N, Kopecky KJ, Sullivan KM, Deeg JH, Sosa R, Noel DR, Atkinson K, Thomas ED: Recovery of antibody production in human allogeneic marrow graft recipients: Influence of time posttransplantation, the presence 1708 or absence of chronic graft-versus-host disease, and antithymocyte globulin treatment. Blood 58:360, 1981
15. Ochs HD, Lum LG, Johnson FL, Schiffman G, Wedgwood RJ, Storb R: Bone marrow transplantation in the Wiskott-Aldrich syndrome. Complete hematological and immunological reconstitution. Transplantation 34:284, 1982
16. Noel DR, Witherspoon RP, Storb R, Atkinson K, Doney K, Mickelson EM, Ochs HD, Warren RP, Weiden PL, Thomas ED: Does graft-versus-host disease influence the tempo of immunologic recovery after allogeneic human marrow transplantation? An observation on 56 long-term survivors. Blood 51:1087, 1978
17. Witherspoon RP, Kopecky K, Storb RF, Floumoy N, Sullivan KM, Sosa R. Deeg HJ, Ochs HD, Cheever MA, Fefer A, Thomas ED: Immunological recovery in 48 patients following syngeneic marrow transplantation for hematological malignancy. Transplantation 33:143, 1982
18. Nonoyama S, Farrington M, Ishida H, Howard M, Ochs HD: Activated B cells from patients with common variable immune deficiency proliferate and synthesize immunoglobulin. J Clin Invest 92:1282, 1993
19. Ochs HD, Davis SD, Wedgwood RJ: Immunologic responses to bacteriophage øX-174 in immunodeficiency diseases. J Clin Invest 50:2559, 1971
20. Wedgwood RJ, Ochs HD, Davis SD: The recognition and classification of immunodeficiency diseases with bacteriophage øX-174, in Bergsma D (ed): Immunodificiency in Man and Animals. March of Dimes Birth Defects Original Article Series, vol 11. Sunderland, MA, Sinauer Assoc, 1975, p 331
21. Ochs HD, Slichter SJ, Harker LA, Von Behrens WE, Clark RA, Wedgwood RJ: The Wiskott-Aldrich syndrome: Studies of lymphocytes, granulocytes, and platelets. Blood 55:243, 1980
22. + colony-forming cell types in blood and marrow of baboons. Blood 80:920, 1992
23. Manning CH, Heise ER: Establishment and characterization of Macaca fascicularis lymphoblastoid cell lines. J Med Primatol 21:15, 1992
24. Reitsma MJ, Palavicini M, Harrison MR: Detection of a malespecific sequence in non-hurnan primates through use of the polymerase chain reaction. Cytogenet Cell Genet 64:213, 1993
25. Tsai CC, Giddens WE Jr, Ochs HD, Morton WR, Knitter GH, Blakley GA, Benveniste RE: Retroperitoneal fibromatosis and acquired immunodeficiency syndrome in macaques: Clinical and immunologic studies. Lab Animal Sci 36:119, 1986
26. Grubb R, Swahn B: Destruction of some aglutinins, but not of others by two sulfhydryl compounds. Acta Pathol Microbiol Scand 43:305, 1958
27. Molgaard HV, Spurr NK, Greaves MF: The hemopoietic stem cell antigen, CD34, is encoded by a gene located on chromosome 1. Leukemia 3:773, 1989
28. Brown J, Greaves MF, Molgaard HV: The gene encoding the stem cell antigen, CD34, is conserved in mouse and expressed in haemopoietic progenitor cell lines, brain, and embryonic fibroblasts. Int Immunol 3:175, 1991
29. Simmons DL, Satterthwaite AB, Tenen DG, Seed B: Molecular cloning of a cDNA encoding CD34, a sialomucin of human hematopoietic stem cells. J Immunol 148:267, 1992
30. He X-Y, Antao VP, Basila D, Marx JC, Davis BR: Isolation and molecular characterization of the human CD34 gene. Blood 79:2296, 1992
31. Andrews RG, Singer JW, Bernstein ID: Monoclonal antibody 12.8 recognizes a 115-kD molecule present on both unipotent and multipotent colony-forming cells and their precursors. Blood 67:842, 1986
32. Shpall EJ, Jones RB, Bearman SI. Purdy MH, Franklin WA, Heimfeld S, Berenson RJ: Transplantation of CD34+ hematopoietic progenitor cells. J Hematother 3:145, 1994
33. Pyun KH, Ochs HD, Wedgwood RJ, Yang XQ, Heller SR, Reimer CB: Human antibody responses to bacteriophage øX-174: Sequential induction of IgM and IgG subclass antibody. Clin Immunol Immunopathol 51:252, 1989
34. Ochs HD, Sullivan JL, Wedgwood RJ, Seeley JK, Sakamoto K, Purtilo DT: X-linked lymphoproliferative syndrome: Abnormal antibody responses to bacteriophage øX-174. Birth Defects 19:321, 1983
35. Junker AK, Ochs HD, Clark EA, Puterman ML, Wedgwood RJ: Transient immune deficiency in patients with acute Epstein-Barr virus infection. Clin lmmunol Immunopathol 40:436, 1986
36. Bernstein LJ, Ochs HD, Wedgwood RJ, Rubenstein A: Defective humoral immunity in pediatric acquired immune deficiency syndrome. J Pediatr 107:352, 1985
37. Ochs HD, Nonoyama S, Farrington ML, Fischer SH, Aruffo A: The role of adhesion molecules in the regulation of antibody responses. Semin Hematol 30:72, 1993 (suppl 4)
38. Price TH, Ochs HD, Gershoni-Baruch R, Harlan JM, Etzioni A: In vivo neutrophil and lymphocyte function studies in a patient with leukocyte adhesion deficiency type II. Blood 84:1635, 1994
39. Witherspoon RP, Sullivan KM, Lum LG, Goehle S, Atkinson MK, Ochs HD, Doney KC, Hansen JA, Sanders JE, Storb R: Use of thymic grafts or thymic factors to augment immunologic recovery after bone marrow transplantation: Brief report with 2 to 12 years' follow-up. Bone Marrow Transplant 3:425, 1988
40. Witherspoon R, Noel D, Storb R, Ochs HD, Thomas ED: The effect of graft-versus-host disease on reconstitution of the immune system following marrow transplantation for aplastic anemia or leukemia. Transplant Proc 10:233, 1978
41. Hamilton BL, Ochs HD: Immune dysfunction associated with graft-versus-host reaction in mice transplanted across minor histocompatibility barriers. I. Depressed antigen-specific antibody responses to bacteriophage øX-174. Transplantation 47:1061, 1989
42. Eberle R, Black DH, Lipper S, Hilliard JK: Herpesvirus papio 2, SA-8 like alpha-herpesvirus of baboons. Arch Virol 140:539, 1995
43. Mone J, Whitehead E, Leland M, Hubbard G, Allan JS: Simian T-cell leukemia virus type I infection in captive baboons. AIDS Res Hum Retroviruses 8:1653, 1992
44. Suda J, Sudo T, Ito M, Ohno N, Yamaguchi Y, Suda T: Two types of murine CD34 mRNA generated by alternative splicing. Blood 79:2288, 1992
45. Krause DS, Ito T, Fackler MJ, Smith OM, Collector MI, Sharkis SJ, May WS: Characterization of murine CD34, a marker for hematopoietic progenitor and stem cells. Blood 84:691, 1994
46. Baumhueter S, Dybdal N, Kyle C, Lasky LA: Global vascular expression of murine CD34, a sialomucin-like endothelial ligand for L-selectin. Blood 84:2554, 1994
47. Osawa M, Hanada K, Hamada H, Nakauchi H: Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 273:242, 1996
48. McSweeney PA, Rouleau KA, Storb R, Bolles L, Wallace PM, Beauchamp M, Krizanac-Bengez L, Moore P, Sale G, Sandmaier B, de Revel T, Appelbaum FR, Nash RA: Canine CD34: Cloning of the cDNA and evaluation of an antiserum to recombinant protein. Blood 88:1992, 1996