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Volumn 38, Issue 7, 1997, Pages 1496-1500

Prolonged inhibition of cholesterol synthesis explains the efficacy of atorvastatin

Author keywords

HMG CoA reductase; Low density lipoprotein; Mevalonic acid; Simvastatin

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; ATORVASTATIN; SIMVASTATIN;

EID: 0030843232     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (80)

References (24)
  • 2
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Scandinavian Simvastatin Survival Study Group. 1994. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet. 344: 1383-1389.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 4
    • 0029099549 scopus 로고
    • Angiographic trials of lipid-lowering therapy: End of an era?
    • Thompson, G. R. 1995. Angiographic trials of lipid-lowering therapy: end of an era? Br. Heart J. 74: 343-347.
    • (1995) Br. Heart J. , vol.74 , pp. 343-347
    • Thompson, G.R.1
  • 5
    • 0029563359 scopus 로고
    • Percentage change rather than plasma level of LDL-cholesterol determines therapeutic response in coronary heart disease
    • Thompson, G. R., J. Hollyer, and D. D. Waters. 1995. Percentage change rather than plasma level of LDL-cholesterol determines therapeutic response in coronary heart disease. Curr. Opin. Lipidol. 6: 386-388.
    • (1995) Curr. Opin. Lipidol. , vol.6 , pp. 386-388
    • Thompson, G.R.1    Hollyer, J.2    Waters, D.D.3
  • 8
    • 0344219472 scopus 로고    scopus 로고
    • Atorvastatin augments therapy of homozygous familial hypercholesterolemia by inhibiting up-regulation of cholesterol synthesis after apheresis and bile acid sequestrants
    • Naoumova, R. P., D. Marais, J. C. Firth, C. K. Y. Neuwirth, G. W. Taylor, and G. R. Thompson. 1996. Atorvastatin augments therapy of homozygous familial hypercholesterolemia by inhibiting up-regulation of cholesterol synthesis after apheresis and bile acid sequestrants. Circulation. 94: I-583.
    • (1996) Circulation , vol.94
    • Naoumova, R.P.1    Marais, D.2    Firth, J.C.3    Neuwirth, C.K.Y.4    Taylor, G.W.5    Thompson, G.R.6
  • 9
    • 0030050055 scopus 로고    scopus 로고
    • Plasma mevalonic acid, an index of cholesterol synthesis in vivo, and responsiveness to HMG-CoA reductase inhibitors in familial hypercholesterolaemia
    • Naoumova, R. P., A. D. Marais, J. Mountney, J. C. Firth, N. B. Rendell, G. W. Taylor, and G. R. Thompson. 1996. Plasma mevalonic acid, an index of cholesterol synthesis in vivo, and responsiveness to HMG-CoA reductase inhibitors in familial hypercholesterolaemia. Atherosclerosis. 119: 203-213.
    • (1996) Atherosclerosis , vol.119 , pp. 203-213
    • Naoumova, R.P.1    Marais, A.D.2    Mountney, J.3    Firth, J.C.4    Rendell, N.B.5    Taylor, G.W.6    Thompson, G.R.7
  • 10
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald, W. T., R. I. Levy, and D. S. Fredrickson. 1972. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 18: 499-502.
    • (1972) Clin. Chem. , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 11
    • 0001921101 scopus 로고
    • Atorvastatin: A step ahead for HMG-CoA reductase inhibitors
    • X. F. P. Woodward, J. Davignon, and A. Sniderman, editors. Elsevier Science Publishers BV, Amsterdam
    • Black, D. M. 1995. Atorvastatin: a step ahead for HMG-CoA reductase inhibitors. In Atherosclerosis X. F. P. Woodward, J. Davignon, and A. Sniderman, editors. Elsevier Science Publishers BV, Amsterdam. 307-310.
    • (1995) Atherosclerosis , pp. 307-310
    • Black, D.M.1
  • 13
    • 0027404607 scopus 로고
    • Simultaneous determination of mevalonate and 7 alpha-hydroxycholesterol in human plasma by gas chromatography-mass spectrometry as indices of cholesterol and bile acid biosynthesis
    • Yoshida, T., A. Honda, N. Tanaka, Y. Matsuzaki, B. He, T. Osuga, N. Kobayashi, K. Ozawa, and H. Miyazaki. 1993. Simultaneous determination of mevalonate and 7 alpha-hydroxycholesterol in human plasma by gas chromatography-mass spectrometry as indices of cholesterol and bile acid biosynthesis. J. Chromatogr. 613: 185-193.
    • (1993) J. Chromatogr. , vol.613 , pp. 185-193
    • Yoshida, T.1    Honda, A.2    Tanaka, N.3    Matsuzaki, Y.4    He, B.5    Osuga, T.6    Kobayashi, N.7    Ozawa, K.8    Miyazaki, H.9
  • 14
    • 0026698745 scopus 로고
    • Correspondence between plasma mevalonic acid levels and deuterium uptake in measuring human cholesterol synthesis
    • Jones, P. J., A. S. Pappu, D. R. Illingworth, and C. A. Leitch. 1992. Correspondence between plasma mevalonic acid levels and deuterium uptake in measuring human cholesterol synthesis. Eur. J. Clin. Invest. 22: 609-613.
    • (1992) Eur. J. Clin. Invest. , vol.22 , pp. 609-613
    • Jones, P.J.1    Pappu, A.S.2    Illingworth, D.R.3    Leitch, C.A.4
  • 15
    • 0024440343 scopus 로고
    • Apolipoprotein E phenotype determined by agarose gel electrofocusing and immunoblotting
    • McDowell, I. F., G. B. Wisdom, and E. R. Trimble. 1989. Apolipoprotein E phenotype determined by agarose gel electrofocusing and immunoblotting. Clin. Chem. 35: 2070-2073.
    • (1989) Clin. Chem. , vol.35 , pp. 2070-2073
    • McDowell, I.F.1    Wisdom, G.B.2    Trimble, E.R.3
  • 16
    • 0029924138 scopus 로고    scopus 로고
    • Role of cholesterol in regulating apolipoprotein B secretion by the liver
    • Thompson, G. R., R. P. Naoumova, and G. F. Watts. 1996. Role of cholesterol in regulating apolipoprotein B secretion by the liver. J. Lipid Res. 37: 439-447.
    • (1996) J. Lipid Res. , vol.37 , pp. 439-447
    • Thompson, G.R.1    Naoumova, R.P.2    Watts, G.F.3
  • 18
    • 0025866394 scopus 로고
    • Comparison between morning and evening doses of simvastatin in hyperlipidemic subjects. A double-blind comparative study
    • Saito, Y., S. Yoshida, N. Nakaya, Y. Hata, and Y. Goto. 1991. Comparison between morning and evening doses of simvastatin in hyperlipidemic subjects. A double-blind comparative study. Arterioscler. Thromb. 11: 816-826.
    • (1991) Arterioscler. Thromb. , vol.11 , pp. 816-826
    • Saito, Y.1    Yoshida, S.2    Nakaya, N.3    Hata, Y.4    Goto, Y.5
  • 19
    • 0023876839 scopus 로고
    • HMG-CoA reductase inhibitors for treatment of hypercholesterolemia
    • Grundy, S. M. 1988. HMG-CoA reductase inhibitors for treatment of hypercholesterolemia. N. Engl. J. Med. 319: 24-33.
    • (1988) N. Engl. J. Med. , vol.319 , pp. 24-33
    • Grundy, S.M.1
  • 20
    • 0029113047 scopus 로고
    • Lipid-lowering activity of atorvastatin and lovastatin in rodent species: Triglyceride-lowering in rats correlates with efficacy in LDL animal models
    • Krause, B. R., and R. S. Newton. 1995. Lipid-lowering activity of atorvastatin and lovastatin in rodent species: triglyceride-lowering in rats correlates with efficacy in LDL animal models. Atherosclerosis. 117: 237-244.
    • (1995) Atherosclerosis , vol.117 , pp. 237-244
    • Krause, B.R.1    Newton, R.S.2
  • 21
    • 0026567257 scopus 로고
    • Hepatic and non-hepatic sterol synthesis and tissue distribution following administration of a liver selective HMG-CoA reductase inhibitor, CI-981: Comparison with selected HMG-CoA reductase inhibitors
    • Bocan, T. M., E. Ferguson, W. McNally, P. D. Uhlendorf, S. Bak Mueller, P. Dehart, D. R. Sliskovic, B. D. Roth, B. R. Krause, and R. S. Newton. 1992. Hepatic and non-hepatic sterol synthesis and tissue distribution following administration of a liver selective HMG-CoA reductase inhibitor, CI-981: comparison with selected HMG-CoA reductase inhibitors. Biochim. Biophys. Acta. 1123: 133-144.
    • (1992) Biochim. Biophys. Acta , vol.1123 , pp. 133-144
    • Bocan, T.M.1    Ferguson, E.2    McNally, W.3    Uhlendorf, P.D.4    Bak Mueller, S.5    Dehart, P.6    Sliskovic, D.R.7    Roth, B.D.8    Krause, B.R.9    Newton, R.S.10
  • 23
    • 0344376485 scopus 로고    scopus 로고
    • Stable isotope turnover studies of apolipoprotein B in combined hyperlipidaemia before and after treatment with atorvastatin, a new HMG-CoA reductase inhibitor
    • Forster, L. F., G. Stewart, D. K. Bedford, J. P. Stewart, M. J. Caslake, C. J. Packard, J. Shepherd, and D. M. Black. 1996. Stable isotope turnover studies of apolipoprotein B in combined hyperlipidaemia before and after treatment with atorvastatin, a new HMG-CoA reductase inhibitor. Circulation. 94: 1-583.
    • (1996) Circulation , vol.94 , pp. 1-583
    • Forster, L.F.1    Stewart, G.2    Bedford, D.K.3    Stewart, J.P.4    Caslake, M.J.5    Packard, C.J.6    Shepherd, J.7    Black, D.M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.