Nonsteroidal Anti-inflammatory drugs, traditional opioids, and tramadol: Contrasting therapies for the treatment of chronic pain

Clinical Therapeutics

Volumn 19, Issue 3, 1997, Pages 420-432

  Aronson, Mark D ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Analgesics; Chronic pain; Pain management; Tramadol

Indexed keywords

ANALGESIC AGENT; DICLOFENAC; KETOPROFEN; MU OPIATE RECEPTOR; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; TRAMADOL;

ARTICLE; CATECHOLAMINE UPTAKE; CHRONIC PAIN; CLINICAL PRACTICE; CONSTIPATION; DRUG CHOICE; DRUG DEPENDENCE; DRUG EFFICACY; DRUG INDICATION; DRUG MECHANISM; DRUG RECEPTOR BINDING; GASTROINTESTINAL TOXICITY; HUMAN; NAUSEA; NEPHROTOXICITY; NEUROTOXICITY; PHYSICIAN; RESPIRATION DEPRESSION; SEIZURE; SEROTONIN UPTAKE; VERTIGO;

EID: 0030842909     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/S0149-2918(97)80127-0     Document Type: Review

References (38)

1. Wall RT III. Use of analgesics in the elderly. Clin Geriatr Med. 1990;6:345-364.
2. Frymoyer JW. Predicting disability from low back pain. Clin Orthop. 1992;279: 101-109.
3. Hiraga K, Mizugachi T, Takeda F. The incidence of chronic pain and improvement in pain management in Japan. Postgrad Med J. 1991:67:514-525.
4. Egbert AM. Help for the hurting elderly: Safe use of drugs to relieve pain. Postgrad Med. 1991;89:217-228.
5. Magni G. The use of antidepressants in the treatment of chronic pain. A review of the current evidence. Drugs. 1991;42: 730-748.
6. Whelton A, Hamilton CW. Nonsteroidal anti-inflammatory drugs: Effects on kidney function. J Clin Pharmacol. 1991; 31:588-598.
7. Murray MD, Brater DC. Nonsteroidal anti-inflammatory drugs. Clin Geriatr Med. 1990;6:365-397.
8. Amadio P Jr, Cummings DM, Amadio O. Nonsteroidal anti-inflammatory drugs: Tailoring therapy to achieve results and avoid toxicity. Postgrad Med. 1993;93: 73-88.
9. Portenoy RK. Cancer pain management. Semin Oncol. 1993;20:19-35.
10. Jaffe JH, Martin JH. Opioid analgesics and antagonists. In: Gilman AG, Rail TW, Nies AS, Taylor P, eds. Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York: Pergamon Press; 1990:485-521.
11. Ultram®. Physicians' Desk Reference®. Montvale, NJ: Medical Economics Company, Inc; 1997:1594-1596.
12. Whitcomb DC, Block GD. Association of acetaminophen hepatotoxicity with fasting and ethanol use. JAMA. 1994;272: 1845-1850.
13. Barkin RL. Alternative dosing for tramadol aids effectiveness. Formulary. 1995;30:542-543. Letter.
14. Gabriel SE, Jaakkimainen L, Bombardier C. Risk for serious gastrointestinal complications related to use of nonsteroidal anti-inflammatory drugs. Ann Intern Med. 1991;115:787-796.
15. Griffin MR, Piper JM, Daugherty JS, et al. Nonsteroidal anti-inflammatory drug use and increased risk of peptic ulcer disease in elderly persons. Ann Intern Med. 1991;1114:251-263.
16. Roth SH. NSAID gastropathy: A new understanding. Arch Intern Med. 1996;156: 1623-1628.
17. Fries JF, Miller SR, Spitz PW, et al. Toward an epidemiology of gastropathy associated with nonsteroidal anti-inflammatory drug use. Gastroenterology. 1989;96: 647-655.
18. Cummings DM, Amadio P Jr. A review of selected newer nonsteroidal anti-inflammatory drugs. Am Fam Phys. 1994;49: 1197-1202.
19. Clive DM, Stoff JS. Renal syndromes associated with nonsteroidal anti-inflammatory drugs. NEJM. 1984;310:563-572.
20. Whelton A. Renal effects of over-the-counter analgesics. J Clin Pharmacol. 1995;35:454-463.
21. Bush TM, Shlotzhauer TL, Imai K. Non-steroidal anti-inflammatory drugs: Proposed guidelines for monitoring toxicity. West J Med. 1991;155:39-42.
22. Johnson AG, Nguyen TV, Day RO. Do nonsteroidal anti-inflammatory drugs affect blood pressure? Ann Intern Med. 1994;121:289-300.
23. Hammack JE, Loprinzi CL. Use of orally administered opioids for cancer-related pain. Mayo Clin Proc. 1994;69:384-390.
24. Portenoy RK. Chronic opioid therapy in nonmalignant pain. J Pain Symptom Manage. 1990;5:S46-S62.
25. Bushnell TG, Justins DM. Choosing the right analgesic. Drugs. 1993;46:394-408.
26. Inturrisi CE. Management of cancer pain: Pharmacology and principles of management. Cancer. 1989;63:2308-2320.
27. Lee CR, McTavish D, Sorkin EM. Tramadol: A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute and chronic pain states. Drugs. 1993;46: 313-340.
28. Grond S, Zech D, Lynch J, et al. Tramadol: A weak opioid for relief of cancer pain. Pain Clinic. 1992;5:241-247.
29. Raffa RB, Friderichs E, Reimann W, et al. Complementary and synergistic antinociceptive interaction between the enantiomers of tramadol. J Pharmacol Exp Ther. 1993;267:331-340.
30. Raffa RB, Friderichs E, Reimann W, et al. Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an "atypical" opioid analgesic. J Pharmacol Exp Ther. 1992; 260:275-285.
31. Yaksh TL, Stevens CW. Properties of the modulation of spinal nociceptive transmission by receptor selective agents. In: Dubner R, Gebhart GF, Bond MR, eds. Pain Research and Clinical Management. Vol. 3. Amsterdam: Elsevier; 1988:418-435.
32. Kayser V, Besson J-M, Guilbaud G. Evidence for the noradrenergic component in the antinociceptive effect of the analgesic agent tramadol in an animal model of clinical pain, the arthritic rat. Eur J Pharmacol. 1992;224:83-88.
33. Rauck RL, Ruoff GE, McMillen JI. Comparison of tramadol and acetaminophen with codeine for long-term pain management in elderly patients. Curr Ther Res. 1994;55:1417-1431.
34. Cossmann M, Wilsmann KM. Effect and side-effect of tramadol. An open phase IV study with 7198 patients. Therapiewoche. 1987;37:3475-3485.
35. Fechner R, Racenberg E, Castor G. Klinische Untersuchungen über die Wirkung von morphin, pentazocin, pethidin, piritramid und tramadol auf die atmung. Anästhesiol Intensivmed. 1985;26:126-132.
36. Preston KL, Jasinski DR, Testa M. Abuse potential and pharmacological comparison of tramadol and morphine. Drug Alcohol Depend. 1991;27:7-17.
37. Kayser V, Besson J-M, Guilbaud G. Effects of the analgesic agent tramadol in normal and arthritic rats: Comparison with the effects of different opioids, including tolerance and cross-tolerance to morphine. Eur J Phamacol. 1991;195:37-45.
38. Cami J, Lamas X, Farre M. Acute effects of tramadol in methadone-maintained volunteers. Drugs. 1994;47(Suppl I):39-43.