Genetics of blood pressure and associated phenotypes in the lyon rat

Clinical and Experimental Hypertension

Volumn 19, Issue 5-6, 1997, Pages 567-575

  Sassard, J ^a   Vincent, M ^a   Orea V ^a   Privat, P ^a   Bataillard, A ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

Genes; Hypertension; Lipids; Rat; Renin

Indexed keywords

ANIMAL EXPERIMENT; BLOOD PRESSURE REGULATION; CONFERENCE PAPER; CONTROLLED STUDY; GENE LOCATION; GENETIC POLYMORPHISM; HYPERTENSION; NONHUMAN; PHENOTYPE; RAT;

EID: 0030842870     PISSN: 10641963     EISSN: None     Source Type: Journal    
DOI: 10.3109/10641969709083170     Document Type: Conference Paper

References (12)

1. Dupont, J., Dupont, J.C., Froment, A., Milon, H., Vincent, M. Selection of three strains of rats with spontaneously different levels of blood pressure. Biomedicine 1973; 19: 36-41.
2. Su, D.F., Cerutti, C., Barrés, C., Vincent, M., Sassard, J. Blood pressure and baroreflex sensitivity in conscious hypertensive rats of Lyon strain. Am. J. Physiol. 1986; 251: H1111-H1117.
3. Cerutti, C., Paultre, C.Z., Barrès, Ch., Sassard, J. Computer analysis of intra arterially recorded blood pressure inconscious unrestrained rats. J. Pharmacol. Methods 1985; 13: 249-260.
4. Dubay, C., Vincent, M., Samani, N.J., Hubert, P., Kaiser, M.A., Beressi, J.P., Kotelevtsev, Y., Beckmann, J.S., Soubrier, F., Sassard, J., Lathrop, G.M. Genetic determinants of diastolic and pulse pressure map to different loci in Lyon hypertensive rats. Nature genetics 1993; 3: 354-357.
5. Rapp, J.P., Wang, S.M., Dene, H. A genetic polymorphism in the renin gene of DaM rats cosegregates with blood pressure. Science 1989; 243: 542-544.
6. Kurtz, T.W., Simonet, L., Kabra, P.M., Wolfe, S., Chan, L., Hjelle, B. L. Cosegregation of the renin allele of the spontaneously hypertensive rat with an increase in blood pressure. J. Clin. Invest. 1990; 85: 1328-1332.
7. Florin, M., Bertram, D., Lo, M., Sassard, J. Lack of persistent effects of angiotensin converting enzyme inhibition (ACE) in Lyon hypertensive (LH) rats. Am. J. Hypertens. 1996; 9: 77A.
8. Rapp, J.P., Dene, H., Deng, A.Y. Seven renin alleles in rats and their effects on blood pressure. J. Hypertens. 1994; 12: 349-355.
9. Samani, N.J., Vincent, M., Sassard, J., Henderson, I.W., Kaiser, M.A., Brammar, W.J., Swales, J.D. Analysis of the renin gene intron A tandem repeat region of Milan and Lyon hypertensive rat strains. J. Hypertens. 1990; 8: 805-809.
10. Vincent, M., Boussairi, E.H., Cartier, R., Lo, M., Sassolas, A., Cerutti, C., Barrès, C., Gustin, M.P., Cuisinaud, G., Samani, N.J., Lathrop G.M., Sassard, J. High blood pressure and metabolic disorders are associated in the Lyon hypertensive rat. J. Hypertens. 1993; 11: 1179-1185.
11. Vincent, M., Cartier, R., Privat, P., Benzoni, D., Samani, N.J., Sassard, J. Major cardiovascular risk factors in Lyon hypertensive rats. A cosegregation study. J. Hypertens. 1996; 14: 469-474.
12. Vincent, M., Sassard, J. The Lyon strains, in: Textbook of Hypertension, J. Swales Ed., Blackwell Scientific Pub. Oxford 1994, p 455-457.