Stereospecific synthesis of tetrasubstituted Z-enol silyl ethers by a three component coupling process

Tetrahedron Letters

Volumn 38, Issue 33, 1997, Pages 5771-5774

  Corey, E J ^a   Lin, Shouzhong ^a   Luo, Guanglin ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SILANE DERIVATIVE;

ARTICLE; CHIRALITY; DRUG PURITY; DRUG SYNTHESIS; IN VITRO STUDY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0030841904     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)01293-8     Document Type: Article

References (7)

1. Corey, E. J.; Lin, S. J. Am. Chem. Soc. 1996, 118, 8765.
2. For the method of preparation see: Nowick, J. S.; Danheiser, R. L. Tetrahedron 1988, 44, 4113.
3. For reviews on synthesis of acylsilanes, see: (a) Ricci, A.; Degl'Innocenti, A. Synthesis 1989, 647.
4. (b) Bulman Page, P. C.; Klair, S. S.; Rosenthal, S. Chem. Soc. Rev. 1990, 19, 147.
5. For prior work on silyl imines, see: Niznik, G. E.; Morrison, W. H. III; Walborsky, H. M. J. Org. Chem. 1974, 39, 600.
6. Yanagisawa, A.; Yasue, K.; Yamamoto, H. Synlett 1993, 686.
7. We are grateful to the National Institutes of Health for a Postdoctoral Fellowship to S. L. and a grant in support of this research.