Application of micronucleus in vitro assay to micropollutants in river water

Water Science and Technology

Volumn 35, Issue 8, 1997, Pages 9-13

  Chung, Youn Son ^a   Ichikawa, Kazuhiro ^a   Utsumi, Hideo ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Ames Salmonella test; Genotoxicity; Mammalian cell line; Micronucleus in vitro test; Water safety

Indexed keywords

ANIMAL CELL CULTURE; BACTERIA; BIOASSAY; METHANE; METHANOL; MUTAGENS; RIVERS; TOXICITY; WATER BACTERIOLOGY;

AMES SALMONELLA; GENOTOXICITY; MICRONUCLEUS IN VITRO TEST;

WATER ANALYSIS;

DICHLOROMETHANE; METHANOL; RIVER WATER;

AMES TEST; ASSAY; CONFERENCE PAPER; GENOTOXICITY; INTERMETHOD COMPARISON; JAPAN; MAMMAL CELL; MICRONUCLEUS; SALMONELLA TYPHIMURIUM; WATER POLLUTANT; WATER SAMPLING;

ANIMALIA; MAMMALIA; SALMONELLA; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 0030840902     PISSN: 02731223     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0273-1223(97)00145-5     Document Type: Conference Paper

References (12)

1. Aso, S., Hayashi, J., Kusakabe, K., Morooka, S., Sera, N., Horikawa, K. and Tokiwa, H. (1992). Effect of preozonation on mutagenic activity generated by chlorination acid dissolved in water. Wat. Sci. Tech., 25(11), 355-362.
2. IARC (1991). Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 52: Chlorinated Drinking Water; Chlorinated By-Products; Some Other Halogenated Compounds; Cobalt and Cobalt Compounds, International Agency for Research on Cancer, Lyon.
3. Kiyoshige, K., Utsumi, H., Shimbara, S. and Hamada, A. (1992). Colony formation assay using L-929 cells to micropollutants in water. J. Japan Soc. Water Environ., 15(10), 748-755.
4. Kool, H. J. and Kreijl, C. F. V. (1984). Formation and removal of mutagenic activity during drinking water preparation. Water Res., 18(8), 1011-1016.
5. Maron, D. M. and Ames, B. N. (1983). Revised methods for the Salmonella mutagenicity test. Mutation Res., 113, 173-215.
6. Maruoka, S. and Yamanaka, S.-I. (1982). Mutagenicity in Salmonella typhimurium tester strains of XAD-2-Ether extract, recovered from Katsura river water in Kyoto City, and its fractions. Mutation Res., 102, 13-26.
7. Matsuoka, A., Yamazaki, N., Suzuki, T., Hayashi, M. and Sofuni, T. (1993). Evaluation of the micronucleus test using a Chinese hamster cell line as an alternative to the conventional in vitro chromosomal aberration test. Mutation Res., 272, 223-236.
8. Nakamuro, K., Ueno, H. and Sayato, Y. (1992). Evaluation of mutagenicity of municipal river water concentrated using XAD resin column method. Wat. Sci. Tech., 25(11), 293-299.
9. Utsumi, H., Mitade, C. Suzuki, S., Nakazawa, H., Fujita, M. and Hamada, A. (1989). Mutagenicity, tumor promoter-activity and cell toxicity of micropollutants in water. EISEIKAGAKU, 35(4), 273-282.
10. Utsumi, H., Hamada, A., Hayatsu, H., Hashimoto, T. and Aizawa, Y. (1990). Seasonal and basinal variations of mutagenicity of river water. J. Japan Soc. Water Environ., 13(4), 227-234.
11. Utsumi, H., Kiyoshige, K., Mitade, C., Han, K.-S., Hakoda, M., Manabe, H. and Hamada, A. (1992a). Mutagenicity and cytotoxicity of tap and raw water and their potential risk. Wat. Sci. Tech., 26(1-2), 247-254.
12. Utsumi, H., Hakoda, M., Kiyoshige, K., Manabe, H., Mitade, C., Murayama, J., Han, K.-S. and Hamada, A. (1992b). Cytotoxicity and mutagenicity of micropollutants in drinking water. Wat. Sci. Tech., 25(11), 325-332.