Excitotoxicity in the enteric nervous system

Journal of Neuroscience

Volumn 17, Issue 22, 1997, Pages 8804-8816

  Kirchgessner, Annette L ^a   Liu, Min Tsai ^a   Alcantara, Frederick ^a  

^a College Physicians and Surgeons ^*  (United States)

Author keywords

Apoptosis; Bleb formation; Glutamate transporters; Kainic acid; Necrosis; NMDA; Rhodamine 123

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; EXCITATORY AMINO ACID; GLUTAMIC ACID; KAINIC ACID; N METHYL DEXTRO ASPARTIC ACID; RECEPTOR SUBUNIT;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; GUINEA PIG; INTESTINE INJURY; INTESTINE INNERVATION; INTESTINE ISCHEMIA; MALE; MITOCHONDRIAL MEMBRANE; NERVE CELL NECROSIS; NERVE FIBER GROWTH; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL;

EID: 0030840136     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-22-08804.1997     Document Type: Article

References (17)

1. Ankarcrona M, Dypbukt JM, Bonfoco E, Zhivotovsky B, Orrenius S, Lipton SA, Nicotera P (1995) Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15:961-973.
2. Bindokas PV, Miller RJ (1995) Excitotoxic degeneration is initiated at non-random sites in cultured rat cerebellar neurons. J Neurosci 15:6999-7011.
3. 2+ entry via AMPA/KA receptors and excitotoxicity in cultured cerebellar Purkinje cells. J Neurosci 14:187-197.
4. Burns GA, Stephens KE (1995) Expression of mRNA for the N-methyl-D-aspartate (NMDAR1) receptor and vasoactive intestinal polypeptide (VIP) co-exist in enteric neurons of the rat. J Auton Nerv Syst 55:207-210.
5. Burns GA, Stephens KE, Benson JA (1994) Expression of mRNA for the N-methyl-D-aspartate (NMDAR1) receptor by the enteric neurons of the rat. Neurosci Lett 170:87-90.
6. Chen Q, Veenman CL, Reiner A (1996) Cellular expression of ionotropic glutamate receptor subunits on specific striatal neuron types and its implication for striatal vulnerability in glutamate receptor-mediated excitotoxicity. Neuroscience 73:715-731.
7. Choi DW (1988) Glutamate neurotoxicity and diseases of the nervous system. Neuron 1:623-634.
8. Choi DW (1992) Excitotoxic cell death. J Neurobiol 23:1261-1276.
9. Choi DW (1995) Calcium: still center-stage in hypoxic-ischemic neuronal cell death. Trends Neurosci 18:58-60.
10. Choi DW, Maulucci-Gedde MA, Kriegstein AR (1987) Glutamate neurotoxicity in cortical cell culture. J Neurosci 7:357-368.
11. Choi DW, Koh J-Y, Peters S (1988) Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists. J Neurosci 8:185-196.
12. Costa M, Brookes SJH, Steele PA, Gibbins I, Burcher E, Kandiah CJ (1996) Neurochemical classification of myenteric neurons in the guinea-pig ileum. Neuroscience 75:949-967.
13. Craig AM, Blackstone CD, Huganir RL, Banker G (1993) The distribution of glutamate receptors in cultured rat hippocampal neurons: postsynaptic clustering of AMPA-selective subunits. Neuron 10:1055-1068.
14. Petralia RS, Wang Y-X, Wenthold RJ (1994b) The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1. J Neurosci 14: 6102-6120.
15. Rhoads JM, Argenzio RA, Chen W, Gomez GG (1995) Asparagine stimulates piglet intestinal Cl̄ secretion by a mechanism requiring a submucosal glutamate receptor and nitric oxide. J Pharmacol Exp Ther 274:404-412.
16. Wiley JW, Lu Y, Owyang C (1991) Evidence for a glutamatergic neural pathway in the myenteric plexus. Am J Physiol 261:G693-G700.
17. Yau WM, Dorsett JA, Parr EL (1989) Characterization of acetylcholine release from enzyme-dissociated myenteric ganglia. Am J Physiol 256: G233-G239.