Examination of telomere lengths in muscle tissue casts doubt on replicative aging as cause of progression in Duchenne muscular dystrophy

Pediatric Research

Volumn 42, Issue 2, 1997, Pages 226-231

  Oexle, Konrad ^a   Zwirner, Angelika ^a   Freudenberg, Klaus ^b   Kohlschütter, Alfried ^c   Speer, Astrid ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b Firma Datenmühle   (Germany)

^c UNIVERSITY OF HAMBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ADOLESCENT; ADULT; AGED; AGING; ARTICLE; ATAXIA TELANGIECTASIA; BECKER MUSCULAR DYSTROPHY; CELL AGING; CHILD; CHROMOSOME BREAKAGE; CONTROLLED STUDY; DUCHENNE MUSCULAR DYSTROPHY; HUMAN; HUMAN TISSUE; INFANT; LIMB GIRDLE MUSCULAR DYSTROPHY; NEWBORN; PRIORITY JOURNAL; SATELLITE CELL; TELOMERE; TURNOVER TIME;

EID: 0030839985     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-199708000-00016     Document Type: Article

References (50)

1. Watson JD 1972 Origin of concatemeric T7 DNA. Nat New Biol 239:197-201
2. Olovnikov AM 1973 A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon. J Theor Biol 41:181-190
3. Allsopp RC, Chang E, Kasheti-Aazam M, Rogaev EI, Piatyszek MA, Shay JW, Harley CB 1995 Telomere shortening is associated with cell division in vitro and in vivo. Exp Cell Res 220:194-200
4. Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PLC, Coviello GM, Wright WE, Weinrich SL, Shay JW 1994 Specific association of human telomerase activity with immortal cells and cancer. Science 266:2011-2015
5. Holt SE, Shay JW, Wright WE 1996 Refining the telomere-telomerase hypothesis of aging and cancer. Nat Biotech 14:836-839
6. Harley CB, Futcher AB, Greider CW 1990 Telomeres shorten during ageing of human fibroblasts. Nature 345:458-460
7. Hastie ND, Dempster M, Dunlop MG, Thompson AM, Green DK, Allshire RC 1990 Telomere reduction in human colorectal carcinoma and with ageing. Nature 346:866-868
8. Allsopp RC, Vaziri H, Patterson C, Goldstein S, Younglai EV, Futcher AB, Greider CW, Harley CB 1992 Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci USA 89:10114-10118
9. Vaziri H, Schächter F, Uchida I, Wei L, Zhu X, Effros R, Cohen D, Harley CB 1993 Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am J Hum Genet 52:661-667
10. Kruk PA, Rampino NJ, Bohr VA 1995 DNA damage and repair in telomeres: relation to aging. Proc Natl Acad Sci USA 92:258-262
11. Kitada T, Seki S, Kawakita N, Kuroki T, Monna T 1995 Telomere shortening in chronic liver diseases. Biochem Biophys Res Commun 211:33-39
12. Blau HM, Wehster C, Pavlath GK 1983 Defective myoblasts identified in Duchenne muscular dystrophy. Proc Natl Acad Sci USA 80:4856-4860
13. Webster C, Blau HM 1990 Accelerated age-related decline in replicative life-span of Duchenne muscular dystrophy myoblasts: implications for cell and gene therapy. Somat Cell Mol Genet 16:557-565
14. Webster C, Filippi G, Rinaldi A, Mastropaolo C, Tondi M, Siniscalco M, Blau HM 1986 The myoblast defect identified in Duchenne muscular dystrophy is not a primary expression of the DMD mutation. Hum Genet 74:74-80
15. Hurko O, McKee L, Zuurveld J, Swick HM 1987 Comparison of Duchenne and normal myoblasts froin a heterozygote. Neurology 37:675-681
16. Ishimoto S, Goto I, Ohta M, Kuroiwa Y 1983 A quantitative study of the muscle satellite cells in various neuromuscular disorders. J Neurol Sci 62:303-314
17. Engel AG, Yamamoto M, Fischbeck KH 1994 Dystrophinopathies. In: Engel AG, Franzini-Armstrong C (eds) Myology. Vol 2, 2nd Ed. McGraw-Hill, New York, pp 1133-1187
18. Baloh R, Cancilla PA, Kalyanaraman K, Munsat T, Pearson CM, Rich R 1972 Regeneration of human muscle. A morphological and histochemical study of normal and dystrophic muscle after injury. Lab Invest 26:319-328
19. Ontell M 1986 Muscular dystrophy and muscle regeneration. Hum Pathol 17:673-682
20. Sadeh M, Czyzewski K, Stern LZ 1985 Chronic myopathy induced by repeated bupivacaine injections. J Neurol Sci 67:229-238
21. Röhme D 1981 Evidence for a relationship between longevity of mammalian species and life spans of normal fibroblasts in vitro and erythrocytes in vivo. Proc Natl Acad Sci USA 78:5009-5013
22. de Haan JB, Cristiano F, Iannello R, Bladier C, Keiner MJ, Kola I 1996 Elevation in the ratio of Cu/Zn-superoxide dismutase 10 glutathione peroxidase activity induces features of cellular senescence and this effect is mediated by hydrogen peroxide. Hum Mol Genet 5:283-292
23. Burr IM, Asayama K, Fenichel GM 1987 Superoxide dismutases, glutathione peroxidase, and catalase in neuromuscular disease. Muscle Nerve 10:150-154
24. Asayama K, Hayashibe H, Dobashi K, Kato K 1989 Lipid peroxide and antioxidant enzymes in muscle and nonmuscle of dystrophic mouse. Muscle Nerve 12:742-748
25. Austin L, de Niese M, McGregor A, Arthur H, Gurusinghe A, Gould MK 1992 Potential oxyradical damage and energy status in individual muscle fibres from degenerating muscle diseases. Neuromuscul Disord 2:27-33
26. Oexle K, Herrmann F, Dodé C, Leturcq F, Hübner C, Kaplan J-C, Mizuno Y, Ozawa E, Campbell KP, Voit T 1996 Neurosensory hearing loss in secondary adhalinopathy. Neuropediatrics 27:32-36
27. Kastan M 1995 Ataxia-telangiectasia - broad implications for a rare disorder. N Engl J Med 333:662-663
28. Weemaes CMR, Smeets DFCM, van der Burgt CJAM 1994 Nijmegen breakage syndrome: a progress report. Int J Radiat Biol 66:S185-S188
29. Davies KE, Speer A, Herrmann F, Spiegler AWJ, McGlade F, Hofker MH, Briand P, Hanke R, Schwartz M, Steinbicker V, Szibor R, Körner H, Sommer D, Pearson PL, Coutelle C 1985 Human X chromosome markers and Duchenne muscular dystrophy Nucleic Acids Res 13:3419-3426
30. Stellwagen NC 1987 Electrophoresis of DNA in agarose and polyacrylamide gels. Adv Electrophor 1:177-228
31. Mehle C, Ljungberg B, Roos G 1994 Telomere shortening in renal cell carcinoma. Cancer Res 54:236-241
32. Southern EM 1979 Measurement of DNA length by gel electrophoresis. Anal Biochem 100:319-323
33. Schmalbruch H, Hellhammer U 1976 The number of satellite cells in normal human muscle. Anat Rec 185:279-282
34. Schmalbruch H, Hellhammer U 1977 The number of nuclei in adult rat muscles with special reference to satellite cells. Anat Rec 189:169-176
35. Bell CD, Conen PE 1968 Histopathological changes in Duchenne muscular dystrophy. J Neurol Sci 7:529-544
36. Mastaglia FL, Kakulas BA 1969 Regeneration in Duchenne muscular dystrophy: a histological and histochemical study. Brain 92:809-818
37. Arahata K, Engel AG 1984 Monoclonal antibody analysis of mononuclear cells in myopathies. I. Quantitation of subsets according to diagnosis and sites of accumulation and demonstration and counts of muscle fibers invaded by T cells. Ann Neurol 16:193-208
38. Arahata K, Engel AG 1988 Monoclonal antibody analysis of mononuclear cells in myopathies. IV. Cell-mediated cytotoxicity and muscle fiber necrosis. Ann Neurol 23:168-173
39. von Zglinicki T, Saretzki G, Docke W, Lotze C 1995 Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence? Exp Cell Res 220:186-193
40. Gilad S, Khosravi R, Shkedy D, Uziel T, Ziv Y, Savitsky K, Rotman G, Smith S, Chessa L, Jorgensen TJ, Harnik R, Frydman M, Sanal O, Portnoi S, Goldwicz Z, Jaspers NGJ, Gatti RA, Lenoir G, Lavin MF, Tatsumi K, Wegner RD, Shiloh Y, Bar-Shira A 1996 Predominance of null mutations in ataxia-telangiectasia. Hum Mol Genet 5:433-439
41. Metcalfe JA, Parkhill J, Campbell L, Stacey M, Biggs P, Byrd PJ, Taylor AMR 1996 Accelerated telomere shortening in ataxia telangiectasia. Nat Genet 13:350-353
42. Delaporte C, Dehaupas M, Fardeau M 1984 Comparison between the growth pattern of cell cultures from normal and Duchenne dystrophic muscle. J Neurol Sci 64:149-160
43. Jasmin G, Tamil C, Vanasse M, Brochu P, Simoneau R 1984 Impaired muscle differentiation in explant cultures of Duchenne muscular dystrophy. Lab Invest 50:197-207
44. Carlson BM, Hansen-Smith FM, Magon DK 1979 The life history of a free muscle graft. In: Mauro A (ed) Muscle Regeneration. Raven Press, New York, pp 493-507
45. Nonaka I, Takagi A, Sugita H 1981 The significance of type 2C muscle fibers in Duchenne muscular dystrophy. Muscle Nerve 4:326-333
46. Miike T 1983 Maturational defect of regenerating muscle fibers in cases with Duchenne and congenital muscular dystrophies. Muscle Nerve 6:545-552
47. Hiyama K, Hirai Y, Kyoizumi S, Akiyama M, Hiyama E, Piatyszek MA, Shay JW, Ishioka S, Yamakido M 1995 Activation of telomerase in human lymphocytes and hematopoietic progenitor cells. J Immunol 155:3711-3715
48. Schmalbruch H 1984 Regenerated muscle fibers in Duchenne muscular dystrophy: a serial section study. Neurology 34:60-65
49. Lee KH, Back MY, Moon KY, Song WK, Chung CH, Ha DB, Kang M-S 1994 Nitric oxide as a messenger molecule for myoblast fusion. J Biol Chem 269:14371-14374
50. Brenman JE, Chao DS, Xia H, Aldape K, Bredt DS 1995 Nitric oxide synthase complexed with dystophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy. Cell 82:743-752