Alterations in thromboxane synthase and thromboxane A2 receptors in experimental alcoholic liver disease

Journal of Pharmacology and Experimental Therapeutics

Volumn 282, Issue 2, 1997, Pages 1037-1043

  Nanji, Amin A ^a,b   Rahemtulla, Amir ^a   Maio, Lili ^a   Khwaja, Shamsuddin ^a   Zhao, Shuping ^a   Tahan, Steven R ^a   Thomas, Peter ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

THROMBOXANE A2 RECEPTOR; THROMBOXANE SYNTHASE;

ALCOHOL CONSUMPTION; ALCOHOL LIVER CIRRHOSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; FAT INTAKE; KUPFFER CELL; LIVER CELL; LIVER METABOLISM; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT;

ANIMALS; IMMUNOHISTOCHEMISTRY; LIVER; LIVER DISEASES, ALCOHOLIC; MALE; RATS; RATS, WISTAR; RECEPTORS, THROMBOXANE; RNA, MESSENGER; THROMBOXANE B2; THROMBOXANE-A SYNTHASE;

EID: 0030839893     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. ADACHI, Y., BRADFORD, B. U., GAO, W., BOJES, H. K. AND THURMAN, R.G.: Inactivation of Kupffer cells prevents early alcohol-induced liver injury. Hepatology 20: 453-460, 1994.
2. ADACHI, Y., MOORE, L. E., BRADFORD, B. U., GAO, W. AND THURMAN, R. G.: Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology 108: 218-224, 1995.
3. ALPINI, G., PHILLIPS, J.,O., VROMAN, B. AND LARUSSO, N. F.: Recent advances in the isolation of liver cells. Hepatology 20: 494-514, 1994.
4. ARMSTRONG, R. A. AND WILSON, N. H.: Aspects of the thromboxane receptor system. Gen. Pharmacol. 26: 463-472, 1995.
5. CHOMCZYNSKI, P. AND SACCHI, N.: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
6. DECKER, K.: Biologically active products of stimulated liver macrophages (Kupffer cells). Eur. J. Biochem. 192: 245-261, 1990.
7. FRENCH, S.W., WONG, K., JUI, L., ALBANO, E., HAGBJORK, A. L. AND INGELMAN-SUNDBERG, M.: Effect of ethanol on cytochrome P450 2E1 (CYP 2E1), lipid peroxidation and serum protein adduct formation in relation to liver pathology pathogenesis. Exp. Mol. Pathol. 58: 61-75, 1993.
8. GARCIA-VALDECASAS, J. C., RULL, R., GRANDE, L., FUSTER, J., RIMOLA, A., LACY, L. M., GONZALEZ, F. X., CUGAT, E., PARELLADA, P. AND VISA, J.: Prostacyclin, thromboxane and oxygen free radicals and post-operative liver function in human liver transplantation. Transplantation 60: 662-667, 1995.
9. GORES, G. J., HERMAN, B. AND LEMASTERS, J. J.: Plasma membrane bleb formation and rupture: a common feature of hepatocellular injury. Hepatology 11: 690-698, 1990.
10. HALUSHKA, P. V., MAIS, D. E., MAYEUX, P. R. AND MORINELLI, T. A.: Thromboxane, prostaglandian and leukotriene receptors. Annu. Rev. Pharmacol. Toxicol. 29: 213-239, 1989.
11. HAMBERG, M., SVENNSON, J. AND SAMMUELSSON, B.: Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. Proc. Natl. Acad. Sci. U.S.A. 72: 2994-2998, 1975.
12. 2-induced hepatocyte plasma membrane bleb formation by certain prostaglandins and a proteinase inhibitor. Biochim. Biophys. Acta 1022: 319-324, 1990.
13. 2 receptor in hepatic sinusoidal endothelial cells and its role in endotoxin-induces liver in rats. Hepatology 20: 1281-1286, 1994.
14. ISRAEL, Y. AND ORREGO, H.: Hypermetabolic state hepatocellular expansion and liver blood flow: An interaction triad in alcoholic liver injury. Ann. NY Acad. Sci 492: 303-323, 1987.
15. 2 receptors on human endothelial cells. Circ. Res. 72: 958-965, 1993.
16. 2 in the human circulation. Anal. Biochem. 155: 198-205, 1986.
17. LIEBER, C.S.: Alcohol and the liver: 1994 update. Gastroenterology 106: 1085-1105, 1994.
18. LIEBER, C. S., BARAONA, E., HERNANDEZ-MUNOZ, R., KUBOTA, S., SATO, N., KAWANO, S., MATSUMARA, T. AND INATOMI, N.: Impaired oxygen utilization: a new mechanism for the hepatotoxicity of ethanol in sub-human primates. J. Clin. Invest. 83: 1682-1690, 1989.
19. MARUGG, R. A., GEHR, P. AND DELEEUW, M.: Secondary lysosomes as an integral part of the cytoskeleton: A morphologic study in rat Kupffer cells. J. Struct. Biol. 105: 146-153, 1990.
20. 2 receptors: Characterization and antagonism. Trends Cardiovasc. Med. 1: 157-161, 1991.
21. NANJI, A. A.: Role of eicosanoids in experimental alcoholic liver disease. Alcohol 10: 443-446, 1993.
22. NANJI, A. A. AND FRENCH, S. W.: Dietary linoleic acid is required for development of experimentally-induced alcoholic liver disease. Life Sci. 44: 223-227, 1989.
23. NANJI, A. A., MENDENHALL, C. L. AND FRENCH, S. W.: Beef fat prevents alcoholic liver disease in the rat. Alcoholism: Clin Exp Res 13: 15-19, 1989.
24. NANJI, A. A., SADRZADEH, S. M. H., KHETTRY, U., THOMAS, P. AND YAMANAKA, T.: Protective effects of a novel quinone derivative, (2E)-3-[5-2,3 dimethoxy-6-methyl-1,4-benzoquinoyl)]-2-nonly-2-propenoic acid on experimental alcoholic liver injury. J. Pharmacol. Exp. Ther. 266: 1085-1090, 1993a.
25. 2. Am. J. Pathol. 142: 367-373, 1993b.
26. NANJI, A. A., KHWAJA, S., TAHAN, S. R. AND SADRZADEH, S. M. H.: Plasma levels of a novel noncycIooxygenase-derived prostanoid (8-isoprostane) correlate with severity of liver injury in experimental alcoholic liver disease. J. Pharmacol. Exp. Ther. 269: 1280-1285, 1994a.
27. NANJI, A. A., SADRZADEH, S. M. H., THOMAS, P. AND YAMANAKA, T.: Eicosanoid profile and evidence for endotoxin tolerance in chronic ethanol-fed rats. Life Sci. 55: 611-620, 1994b.
28. 1/S arrest correlates with severity of alcoholic liver injury in the rat. Gastroenterology 107: 818-823, 1994c.
29. NANJI, A. A., ZHAO, S., SADRZADEH, S. M. H. AND WAXMAN, D. J.: Use of reverse transcription-polymerase chain reaction to evaluate in-vivo cytokine gene expression in rats fed ethanol for long periods. Hepatology 19: 1483-1487, 1994d.
30. NANJI, A. A., TAHAN, S. R., KHWAJA, S., GOLDING, M. AND LALANI, E. N.: Role for transforming growth factor-β1 in inhibiting endothelial cell proliferation in experimental alcoholic liver disease. Am. J. Pathol. 148: 739-748, 1996.
31. NANJI, A. A., KHWAJA, S., RAHEMTULLA, A., MIAO, L., ZHAO, S. AND TAHAN, S. R.: Thromboxane inhibitors attenuate pathological changes in alcoholic liver disease in the rat. Gastroenterology 112: 200-207, 1997.
32. NEGISHI, M., SUGIMOTO, Y. AND ICHIKAWA, A.: Prostanoid receptors and their biological actions. Prog. Lipid Res. 32: 417-434, 1993.
33. 2 formation. N. Engl. J. Med. 319: 689-698, 1988.
34. PETRICK, A. T., METERISSIAN, S., STEELE, G. AND THOMAS, P.: Desialytation of metastatic human cobrectal carcinoma cells facilities binding to Kupffer cells. Clin. Exp. Metastasis 12: 108-116, 1994.
35. SCHROR, K. AND BRAUN, M.: Platelets as a source of vasoactive mediators. Stroke 21: suppl IV, 32-35, 1990.
36. SEGLEN, P.: Preparation of rat liver cells III. Enzymatic requirements for tissue dispersion. Exp. Cell. Res. 82: 391-398, 1973.
37. 2 receptors. J. Leukocyte Biol. 53: 173-178, 1993.
38. SMITH, W. L.: Prostanoid biosynthesis and mechanisms of action. Am. J. Physiol. 263: F181-F191, 1992.
39. SPURNEY, R. F., MIDDLETON, J. P., RAYMOND, J. R. AND COFFMAN, T. M.: Modulation of thromboxane receptor activation in rat glomerular mesangial cells. Am. J. Physiol. 267: F467-F478, 1994.
40. TOTH, C. A., THOMAS, P., BROITMAN, S. A AND ZAMCHECK, N.: Receptor-mediated endocytosis of carcinembryonic antigen by rat liver Kupffer cells. Cancer Res. 45: 392-397, 1985.
41. TSUKAMOTO, H., GAAL, K. AND FRENCH, S. W.: Insight into the pathogenesis of alcoholic liver necrosis and fibrosis. Hepatology 12: 599-608, 1990.
42. TSUKAMOTO, H. AND XI, X. P.: Incomplete compensation of enhanced hepatic oxygen consumption with alcoholic centrilobular necrosis. Hepatology 9: 302-306, 1989.
43. WILKES, B. M., KAPLAN, R., MENTO, P. F., AYNEDJIAN, H. S., MACICA, C. M., SCHLONDORFF, D. AND BANK, N.: Reduced glomerular thromboxane receptor sites and vasoconstrictor responses in diabetic rats. Kidney Int. 41: 992-999, 1992.
44. WINWOOD, P. J. AND ARTHUR, M. J. P.: Kupffer cells: their activation and role in animal models of liver injury and human liver disease. Semin. Liver Dis. 13: 50-59, 1993.