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AML1 and the 8;21 and 3:21 translocations in acute and chronic myeloid leukemias
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The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript
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Involvement of the AML1 gene in the t(3;21) in therapyrelated leukemia and in chronic myeloid leukemia in blast crisis
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Nucifora G, Birn DJ, Espinosa R, Erickson P, LeBeau MM, Rouston D, McKeithan TW, Drabkin HA, Rowley JD (1993): Involvement of the AML1 gene in the t(3;21) in therapyrelated leukemia and in chronic myeloid leukemia in blast crisis. Blood 81:2728-2734.
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Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes biastic crisis in chronic myeloid leukemia
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Mitani K, Ogawa S, Tanaka T, Miyoshi H, Kurokawa M, Mano H, Yazaki Y, Ohki M, Hirai H (1994): Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes biastic crisis in chronic myeloid leukemia. EMBO J 13:504-510.
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Detection of rare 21q22 translocation breakpoints within the AML1 gene in myeloid neoplasms by fluorescence in situ hybridization
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The t(12:21) of acute lymphoblastic leukemia results in a TEL-AML1 gene fusion
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An ets-related gene, ERG, is rearranged in human myeloid leukemia with t(16;21) chromosomal translocation
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Shimizu K, Ichikawa H, Tojo A, Kaneko Y, Maseki N, Hayashi Y, Ohira M, Asano S, Ohki M (1993): An ets-related gene, ERG, is rearranged in human myeloid leukemia with t(16;21) chromosomal translocation. Proc Natl Acad Sci USA 90:10280-10284.
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Alternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemia
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Cytogenetics of childhood acute nonlymphocytic leukemia
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0025746321
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t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1
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Miyoshi H, Shimizu K, Kozu T, Maseki N, Kaneko Y, Ohki M (1991): t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1. Proc Natl Acad Sci USA 88:10431-10434.
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