A pilot trial of adjunctive gabapentin in the treatment of bipolar disorder

Annals of Clinical Psychiatry

Volumn 9, Issue 2, 1997, Pages 99-103

  McElroy, Susan L ^a   Soutullo, Cesar A ^a   Keck, Paul E ^a   Kmetz, Geri F ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Bipolar disorder; Gabapentin; Hypomania; Mania; Mixed

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; GABAPENTIN; LITHIUM; VALPROIC ACID;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG EFFICACY; DRUG SAFETY; FEMALE; HUMAN; HYPOMANIA; MALE; MANIA; MANIC DEPRESSIVE PSYCHOSIS; MOOD; NEUROLOGIC DISEASE; PRIORITY JOURNAL;

ACETIC ACIDS; ADJUVANTS, PHARMACEUTIC; ADULT; AFFECT; AMINES; ANTICONVULSANTS; BIPOLAR DISORDER; CYCLOHEXANECARBOXYLIC ACIDS; FEMALE; GAMMA-AMINOBUTYRIC ACID; HUMANS; MALE; MIDDLE AGED; PILOT PROJECTS; TREATMENT OUTCOME;

EID: 0030838965     PISSN: 10401237     EISSN: None     Source Type: Journal    
DOI: 10.3109/10401239709147781     Document Type: Article

References (21)

1. American Psychiatric Association: Work Group on Bipolar Disorder. Practice Guideline for the Treatment of Patients with Bipolar Disorder. Am J Psychiatry 1994;151(Suppl):i-36
2. Bowden C: Treatment of bipolar disorder. In: Nemeroff CB, Schatzberg AS, eds. Textbook of Psychopharmacology. Washington, DC: American Psychiatric Press; 1995: 603-614
3. Calabrese JR, Bowden CB, Woyshville MJ: Lithium and anticonvulsants in the treatment of bipolar disorder. In: Bloom FE, Kupfer DJ, eds, Psychopharmacology: The Fourth Generation of Progress. New York: Raven Press; 1995:1099-1111
4. McElroy SL, Keck PE Jr: Drugs for treatment of bipolar disorder: Anticonvulsants. In: Nemeroff CB, Schatzberg AS (eds): Textbook of Psychopharmacology. Washington, DC: American Psychiatric Press, 1995:351-356
5. UK Gabapentin Study Group: Gabapentin in partial epilepsy. Lancet 1990; 335:1114-1117
6. Bruin J, Sanders M, Anhut H, et al.: Efficacy and safety of gabapentin (Neurontin): A multicenter, placebo-controlled, double-blind study. Neurology 1991; 41 (Suppl 1):330-331
7. U.S. Gabapentin Study Group No. 5: Gabapentin as add-on therapy in refractory partial epilepsy: A double-blind, placebo-controlled, parallel group study. Neurology 1993; 43:2292-2298
8. Browne TR (for the International, U.K., and U.S. Gabapentin Study Groups): Efficacy and safety of gabapentin. In: Chadwick, D, ed. New Trends in Epilepsy Management: The Role of Gabapentin. Royal Society of Medicine Services International Congress and Symposium Series, No. 198. London: Royal Society of Medicine Services, 1993:47-57
9. Chadwick D: Gabapentin. Clinical use. In: Levy RH, Mattson RH, Meldrum BS, eds, Antiepileptic Drugs, 4th ed. New York: Raven Press, 1995:851-856
10. Taylor CP: Gabapentin. Mechanism of action. In: Levy RH, Mattson RH, Meldrum BS, eds. Antiepileptic Drugs, 4th ed. New York, Raven Press, 1995:829-841
11. McLean MJ: Gabapentin. Chemistry, absorption, distribution, and excretion. In: Levy RH, Mattson RH, Meldrum BS, eds. Antiepileptic Drugs, 4th ed. New York: Raven Press, 1995: 843-849
12. Ramsay RE: Gabapentin. Toxicity. In: Levy RH, Mattson RH, Meldrum BS, eds. Antiepileptic Drugs, 4th ed. New York: Raven Press; 1995: 57-860
13. Ryback R, Ryback L: Gabapentin for behavioral dyscontrol (letter). Am J Psychiatry 1995; 152:1399
14. Stanton SP, Keck PE Jr, McElroy SL: Treatment of acute mania with gabapentin (letter). Am J Psychiatry 1997; 154:287
15. Schaffer CB, Schaffer LC: Gabapentin in the treatment of bipolar disorder (letter). Am J Psychiatry 1997; 154:291-292
16. Bennett J, Goldman WT, Suppes T: Gabapentin for treatment of bipolar and schizoaffective disorders (letter). J Clin Psychopharmacol 1997; 17:141-142
17. McElroy SL, Pope HG Jr, Keck PE Jr, et al.: Are impulse control disorders related to bipolar disorder? Comp Psychiatry 1996; 37:229-240
18. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 4th ed. Washington, DC: American Psychiatric Association; 1994
19. Wolf SM, Shinnar S, Kang H, et al.: Gabapentin toxicity in children manifesting as behavioral changes. Epilepsia 1995; 36:1203-1205
20. Lee DO, Steingard RJ, Cesena M, et al.: Behavioral side effects of gabapentin in children. Epilepsia 1996; 37:87-90
21. Short C, Cooke L: Hypomania induced by gabapentin. Br J Psychiatry 1995; 166:679-680