Transient exposure to cytarabine increases peptide growth factor receptor expression and tumorigenicity of melanoma cells

Anticancer Research

Volumn 17, Issue 4 A, 1997, Pages 2369-2375

  Caraglia, Michele ^a   Leardi, Annalisa ^a   Improta, Salvatore ^b   Perin, Vilma ^b   Ricciardi, Beatrice ^a   Arra, Claudio ^c   Ferraro, Paola ^c   Fabbrocini, Antonietta ^a   Pinto, Antonio ^b   Bianco, A Raffaele ^a   Tagliaferri, Pierosandro ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b CENTRO DI RIFERIMENTO ONCOLOGICO   (Italy)

^c NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Adhesion molecules; Cytarabine; Melanoma; Peptide growth factor receptor; Tumorigenicity

Indexed keywords

COLLAGEN TYPE 4; CYTARABINE; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR; INTEGRIN; LAMININ; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; NERVE GROWTH FACTOR RECEPTOR; TRANSFERRIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER INVASION; CARCINOGENESIS; CARCINOGENICITY; CELL ADHESION; CELL PROLIFERATION; CELL SURFACE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; MELANOMA CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CELL ADHESION; CELL CYCLE; CELL DIVISION; CYTARABINE; DRUG ADMINISTRATION SCHEDULE; EPIDERMAL GROWTH FACTOR; HUMANS; INTEGRINS; MELANOMA; MICE; MICE, NUDE; NEOPLASM INVASIVENESS; NEOPLASMS, EXPERIMENTAL; NERVE GROWTH FACTORS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, NERVE GROWTH FACTOR; RECEPTORS, TRANSFERRIN; TRANSFERRIN; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0030838943     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Aaronson SA: Growth factors and cancer. Science 254: 1146-1153, 1991.
2. Ethier SP: Growth factor synthesis and human breast cancer progression. J Natl Cancer Inst 87: 964-973, 1995.
3. Gullick WJ, Marsden JJ, Whittle N, Ward B, Borbrow L and Waterfield MD: Expression of epidermal growth factor receptors on human cervical, ovarian and vulval carcinomas. Cancer Res 46: 285- 292, 1986.
4. Gatter KC, Brown G, Trowbridge IS, Woolston R-E, Mason DY: Transferrin receptors in human tissues: their distribution and possible clinical relevance. J Clin Pathol 36: 539-540, 1983.
5. Caraglia M, Leardi A, Corradino S, Ciardiello F, Budillon A, Guarrasi R, Bianco AR and Tagliaferri P: α-Interferon potentiates epidermal growth factor receptor-mediated effects on human epidermoid carcinoma KB cells. Int J Cancer 61: 342-347, 1995.
6. Caraglia M, Libroia AM, Corradino S, Coppola V, Guarrasi R, Barile C, Genua G, Bianco AR and Tagliaferri P: α-Interferon induces depletion of intracellular iron content and upregulation of functional transferrin receptors on human epidermoid cancer KB cells. Biochem Biophys Res Commun 203: 281-288, 1994.
7. 125I-transferrin and enhances the in vitro targeting of human tumour cells with anti- (growth factor receptor) mAb. Cancer Immunol Immunother 37: 150-156, 1993.
8. Caraglia M, Pinto A, Correale P, Zagonel V, Genua G, Leardi A, Pepe S, Bianco AR and Tagliaferri P: 5-Aza-2′-deoxycytidine induces growth inhibition and upregulation of epidermal growth factor receptor on human epithelial cancer cells. Ann Oncol 5, 269-276, 1994.
9. Tagliaferri P, Caraglia M, Muraro R, Budillon A, Pinto A and Bianco AR: Pharmacological modulation of peptide growth factor receptor expression on tumor cells as a basis for cancer therapy. Anti-Cancer Drugs 5: 379-393, 1994.
10. Ruoslahti E and Pierschbacher MD: New perspectives in cell adhesion, RGD and integrins. Science 238: 491-496, 1987.
11. Anichini A, Mortarini R, Supino R and Parmiani G: Human melanoma cells with high susceptibility to cell-mediated Iysis can be identifiedon the basis of ICAM-1 phenotype, VLA profile and invasive ability. Int J Cancer 46: 508-515, 1990.
12. Anklesaria P, Teixido J, Laiho M, Pierce JH, Greenberger JS and Massague J: Cell-cell adhesion medaited by binding of membrane anchored transformed growth factor-a to epidermal growth factor receptors promotes cell proliferation. Proc Natl Acad Sci USA 87: 3289-3293, 1990.
13. Carmichael J, De Graff WG, Gadzar AF, Minna J and Mitchell JB: Evaluation of a tetrazolium based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res 34: 2243-2245, 1987.
14. Rizzino A, Kazakoff P, Ruff E, Kuszinski C and Nebelsick J: Regulatory effects of cell density on the binding of transforming growth factor-β, epidermal growth factor, platelet derived growth factor and fibroblast growth factor. Cancer Res 48: 4266-4271, 1988.
15. Budillon A, Tagliaferri P, Caraglia M, Torrisi MR, Normanno N, Iacobelli S, Palmieri G, Stoppelli MP, Frati L and Bianco AR: Upregulation of epidermal growth factor receptor induced by alpha- interferon in human epidermoid cancer cells. Cancer Res 51: 1294- 1299, 1991.
16. Real FX, Rettig WJ, Chesa PG, Melamed MR. Old LJ and Mendelsohn J: Expression of epidermal growth factor receptor in human cultured cells and tissues: relationship to cell lineage and stage of differentiation. Cancer Res 46: 4726-4731, 1986.
17. Inoue T, Cavanaugh PG, Steck PA, Brtunner N and Nicolson GL: Differences in transferrin response and numbers of transferrin receptors in rat and human mammary carcinoma lines of different metastatic potentials. J Cell Phys 156: 212-217, 1993.
18. Cavanaugh PG and Nicolson GL: Lung-derived growth factor that stimulates the growth of lung metastasizing tumor cells: Identification as a transferrin. J Cell Biochem 47: 261-271, 1991.
19. Marchetti D, Menter D, Jin L, Nakajima M and Nicolson GL: Nerve growth factor effects on human and mouse melanoma cell invasion and heparanese production. Int J Cancer 55(4): 692-699, 1993.
20. Sung C, Shockley TR, Morrison PF, Dvorak HF, Yarmush ML and Dedrick RL: Predicted and observed effects of antibody affinity and antigen density on monoclonal antibody uptake in solid tumors. Cancer Res 52: 377-384, 1992.
21. Caraglia M, Leardi A, Ricciardi B, de Laurentiis M, Lentini Graziano ML, Matano E, De Placido S, Bianco AR and Tagliaferri P: α- Interferon potentiates the growth inhibitory effects of anti-transferrin receptor monoclonal antibodies. Int J Oncol 8: 847-850, 1996.
22. Caraglia M, Passeggio A, Beninati S, Leardi A, Nicolini L, Improta S, Pinto A Blanco AR, Tagliaferri P and Abbruzzese A: Interferon α2 recombinant and epidermal growth factor modulate proliferation and hypusine synthesis in human epidermoid cancer KB cells. Biochem J, in press.
23. Dudley DT, Pang L, Decker SJ, Bridges AJ and Saltiel AR: A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad USA 92: 7686-7689, 1995.
24. Marom M, Haklai R, Ben-Baruch G, Marciano D, Egozi Y and Kloog Y: Selective inhibition of ras-dependent cell growth by farnesylthiosalicylic acid. J Biol Chem 270: 22263-22270, 1995.