Transforming growth factor-beta and bcl-2 distribution patterns distinguish trichoepithelioma from basal cell carcinoma

Dermatologic Surgery

Volumn 23, Issue 8, 1997, Pages 695-700

  Verhaegh, Marc E J M ^a   Arends, Jan Willem ^a   Majoie, I M Leonie ^a   Hoekzema, Rick ^a   Neumann, H A Martino ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; PROTEIN BCL 2; TRANSFORMING GROWTH FACTOR BETA; TUMOR MARKER;

ADULT; AGED; ARTICLE; BASAL CELL CARCINOMA; CANCER DIAGNOSIS; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PRIORITY JOURNAL; TRICHOEPITHELIOMA;

EID: 0030838896     PISSN: 10760512     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1524-4725.1997.tb00392.x     Document Type: Article

References (15)

1. Ackerman AB, De Viragh PA, Chongchitnant N. Neoplasms with Follicular Differentiation. Philadelphia: Lea and Febiger, 1993; 425-58.
2. Walsh N, Ackerman AB. Infundibulocystic basal cell carcinoma: a newly described variant. Modern Pathol 1990;3:599-608.
3. Kirchmann TT, Prieto VG, Smoller BR. CD34 staining pattern distinguishes basal cell carcinoma from trichoepithelioma. Arch Dermatol 1994;130:589-92.
4. Smoller BR, van de Rijn M, Lebrun D, Warnke RA. Bcl-2 expression reliably distinguishes trichoepitheliomas from basal cell carcinomas. Br J Dermatol 1994;131:28-31.
5. Brooke JD, Fitzpatrick JE, Golitz LE. Papillary mesenchymal bodies: a histologic finding useful in differentiating trichoepitheliomas from basal cell carcinomas. J Am Acad Dermatol 1989;21: 523-8.
6. Ackerman AB, Mendonça AMN, Guo Y. Differential diagnosis in dermatopathology I. Philadelphia: Lea and Febiger, 1992:130-3.
7. Hockenbery DM, Nuñez G, Milliman C, Schreiber RD, Korsmeyer SJ. Bcl-2 is an inner mitochondrial protein that blocks programmed cell death. Nature 1990;348:334-6.
8. Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, Korsmeyer SJ. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993;75:241-51.
9. Verhaegh MEJM, Sanders CJG, Arends JW, Neumann HAM. Expression of the apoptosis-suppressing protein bcl-2 in non-melanoma skin cancer. Br J Dermatol 1995;132:740-4.
10. Andrews RG, Singer JW, Bernstein ID. Monoclonal antibody 12.8 recognizes a 115-kd molecule present on both unipotent and multipotent hematopoietic colony forming cells and their precursors. Blood 1986;67:842-5.
11. Nickoloff BJ. The human progenitor cell antigen (CD34) is localized on endothelial cells, dermal dendritic cells, and perifollicular cells in formalin-fixed normal skin, and on proliferating endothelial cells and stromal spindle-shaped cells in Kaposi's sarcoma. Arch Dermatol 1991;127:523-9.
12. Rizzino A. Transforming growth factor-β: multiple effects on cell differentiation and extracellular matrices. Dev Biol 1988;130:411-22.
13. Stamp GWH, Nasim M, Cardillo M, Sudhindra SG, Lalani EN, Pignatelli M. Transforming growth factor-β distribution in basal cell carcinomas: relationship to proliferation index. Br J Dermatol 1993;129:57-64.
14. Glick AB, Kulkarni AB, Tennenbaum T, et al. Loss of expression of transforming growth factor β in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion. Proc Natl Acad Sci USA 1993;90:6067-80.
15. De Eusebio E, Yus ES, Bran EL, Rojo S, Rueda M, Del Cerro M. Infundibulocystic basaloid neoplasm. J Cutan Pathol 1996;23:147-50.