Insertional editing in isolated Physarum mitochondria is linked to RNA synthesis

RNA

Volumn 3, Issue 8, 1997, Pages 821-837

  Visomirski Robic, Linda M ^a   Gott, Jonatha M ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Mitochondrial RNA polymerase; Nucleotide insertion; Physarum polycephalum; RNA editing; Transcription

Indexed keywords

CYTIDINE; MITOCHONDRIAL RNA; NUCLEOTIDE; RNA POLYMERASE; URIDINE;

ARTICLE; MITOCHONDRION; MYXOMYCOTA; PRIORITY JOURNAL; PROTEIN PROCESSING; RNA ANALYSIS; RNA EDITING; RNA SYNTHESIS; RNA TRANSCRIPTION;

ANIMALS; BASE SEQUENCE; CYTIDINE; CYTIDINE TRIPHOSPHATE; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; NUCLEOTIDES; PHYSARUM POLYCEPHALUM; RNA EDITING; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, PROTOZOAN; TEMPLATES, GENETIC; TRANSCRIPTION, GENETIC;

CHONDROMYCES; MYXOGASTRIA; PHYSARUM; PHYSARUM POLYCEPHALUM;

EID: 0030838694     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Bakalara N, Simpson AM, Simpson L. 1989. The Leishmania kinetoplast-mitochondrion contains terminal uridylyltransferase and RNA ligase activities. J Biol Chem 264:18679-18686.
2. Blum B, Bakalara N, Simpson L. 1990. A model for RNA editing in kinetoplastid mitochondria: "Guide" RNA molecules transcribed from maxicircle DNA provide the edited information. Cell 60:189-198.
3. Blum B, Strum NR, Simpson AM, Simpson L. 1991. Chimeric gRNA-mRNA molecules with oligo(U) tails covalently linked at sites of RNA editing suggest thet U addition occurs by transesterification. Cell 65:543-550.
4. Borukhov S, Polyakov A, Nikiforov V, Goldfarb A. 1992. GreA protein: A transcription elongation factor from Escherichia coli. Proc Natl Acad Sci USA 89:8899-8902.
5. Borukhov S, Sagitov V, Goldfarb A. 1993. Transcript cleavage factors from E. coli. Cell 72:459-466.
6. Cech TR. 1991. RNA editing: World's smallest introns? Cell 64:667-669.
7. Cermakian N, Ikeda TM, Cedergren R, Gray MW. 1996. Sequences homologous to yeast mitochondrial and bacteriophage T3 and T7 RNA polymerases are widespread throughout the eukaryotic lineage. Nucleic Acids Res 24:648-654.
8. Corell RA, Feagin JE, Riley GR, Strickland T, Guderian JA, Myler PJ, Stuart K. 1993. Trypanosoma brucei minicircles encode multiple guide RNAs which can direct editing of extensively overlapping sequences. Nucleic Acids Res 21:4313-4320.
9. Deutscher MP. 1972. Synthesis and functions of the -C-C-A terminus of transfer RNA. Prog Nucleic Acids Res 13:51-92.
10. Erie DA, Hajiseyedtavadi O, Young MC, vonHippel PH. 1993. Multiple RNA polymerase conformations and GreA: Control of the fidelity of transcription. Science 262:867-873.
11. Feng GH, Lee DN, Wang DG, Chan CL, Landick R. 1994. GreA-induced transcript cleavage in transcription complexes containing Escherichia coli RNA polymerase is controlled by multiple factors, including nascent transcript location and structure. J Biol Chem 269:22282-22294.
12. Gott JM, Visomirski LM, Hunter JL. 1993. Substitutional and insertional RNA editing of the cytochrome c oxidase subunit 1 mRNA of Physarum polycephalum. J Biol Chem 268:25483-25486.
13. Greider CW, Blackburn EH. 1989. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature 337:331-337.
14. Hausmann S, Jacques JP, Kolakofsky D. 1996. Paramyxovirus RNA editing and the requirement for hexamer genome length. RNA 2:1033-1045.
15. Izban MG, Luse DS. 1992. The RNA polymerase II ternary complex cleaves the nascent transcript in a 3′ → 5′ direction in the presence of elongation factor SII. Genes & Dev 6:1342-1356.
16. Jacques JP, Kolakofsky D. 1991. Pseudo-templated transcription in prokaryotic and eukaryotic organisms. Genes & Dev 5:707-713.
17. Kable ML, Seiwert SD, Heidmann S, Stuart K. 1996. RNA editing: A mechanism for gRNA-specified uridylate insertion into precursor mRNA. Science 273:1189-1195.
18. Komissarova N, Kashlev M. 1997. Transcriptional arrest: Escherichia coli RNA polymerase translocates backward, leaving the 3′ end of the RNA intact and extruded. Proc Natl Acad Sci USA 94:1755-1760.
19. Mahendran R, Spottswood MS, Ghate A, Ling Ml, Jeng K, Miller DL. 1994. Editing of the mitochondrial small subunit rRNA in Physarum polycephalum. EMBO J 13:232-240.
20. Mahendran R, Spottswood MR, Miller DL. 1991. RNA editing by cytidine insertion in mitochondria of Physarum polycephalum. Nature 349:434-438.
21. Masiakski P, Deutscher MP. 1980. Dissection of the active site of rabbit liver tRNA nucleotidyltransferase. J Biol Chem 255:11240-11246.
22. Maslov DA, Simpson L. 1992. The polarity of editing within a multiple gRNA-mediated domain is due to formation of anchors for upstream gRNAs by downstream editing. Cell 70:459-467.
23. Miller D, Mahendran R, Spottswood M, Costandy H, Wang S, Ling Ml, Yang N. 1993a. Insertional editing in mitochondria of Physarum. Sem Cell Biol 4:261-266.
24. Miller D, Mahendran R, Spottswood M, Ling M, Wang S, Yang N, Costandy H. 1993b. RNA editing in mitochondria of Physarum polycephalum. In: Benne R, ed. RNA editing: The alteration of protein coding sequences of RNA. New York: Ellis Horwood. pp 87-103.
25. Milligan JF, Groebe DR, Witherel GW, Uhlenbeck OC. 1987. Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates. Nucleic Acids Res 15:8783-8798.
26. Paterson RG, Lamb RA. 1990. RNA editing by G-nucleotide insertion in mumps virus P-gene mRNA transcripts. J Virol 64:4137-4145.
27. Reines D. 1992. Elongation factor-dependent transcript shortening by template-engaged RNA polymerase II. J Biol Chem 267:3795-3800.
28. Reines D. 1994. Nascent RNA cleavage by transcription elongation complexes. In: Conaway RC, Conaway JW, eds. Transcription: Mechanisms and regulation. New York: Raven Press, Ltd. pp 263-278.
29. Reines D, Conaway JW, Conaway RC. 1996. The RNA polymerase II general elongation factors. Trends Biochem Sci 21:351-355.
30. Reines D, Ghanoun P, Li Qq, Mote J. 1992. The RNA polymerase II elongation complex: Factor-dependent transcription elongation involves nascent RNA cleavage. J Biol Chem 267:15516-15522.
31. Rudd MD, Izban MG, Luse DS. 1994. The active site of RNA polymerase II participates in transcript cleavage within arrested ternary complexes. Proc Natl Acad Sci USA 91:8057-8061.
32. Rundquist BA, Gott JM. 1995. RNA editing of the col mRNA throughout the life cycle of Physarum polycephalum. Mol Gen Genet 247:306-311.
33. Sanchez A, Trappier SG, Mahy BWJ, Peters CJ, Nichol ST. 1996. The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing. Proc Natl Acad Sci USA 93:3602-3607.
34. Scott J. 1995. A place in the world for RNA editing. Cell 81:833-836.
35. Severinov K, Goldfarb A. 1994. Topology of the product binding site in RNA polymerase revealed by transcript slippage at the phage lambda P-L promoter. J Biol Chem 269:31701-31705.
36. Simpson L, Emeson RB. 1996. RNA editing. Annu Rev Neurosci 19:27-52.
37. Simpson L, Thiemann OH. 1995. Sense from nonsense: RNA editing in mitochondria of kinetoplastid protozoa and slime molds. Cell 81:837-840.
38. Stuart K, Allen TE, Heidmann S, Seiwert SD. 1997. RNA editing of kinetoplastid protozoa. Microbiol Mol Biol Rev 61:105-120.
39. Sugisaki H, Takanami M. 1993. The 5′ terminal region of the apocytochrome b transcript in Crithidia fasciculata is successively edited by two guide RNAs in the 3′ to 5′ direction. J Biol Chem 268:887-891.
40. Surratt CK, Milan SC, Chamberlin MJ. 1991. Spontaneous cleavage of RNA in ternary complexes of Escherichia coli RNA polymerase and its significance for the mechanism of transcription. Proc Natl Acad Sci USA 88:7983-7987.
41. Thomas SM, Lamb RA, Paterson RG. 1988. Two mRNAs that differ by two nontemplated nucleotides encode the amino coterminal proteins P and V of the paramyxovirus SV5. Cell 54:891-902.
42. Vidal S, Curran J, Kolakofsky D. 1990a. A stuttering model for paramyxovirus P mRNA editing. EMBO J 9:2017-2022.
43. Vidai S, Curran J, Kolakofsky D. 1990b. Editing of the Sendai virus P/C mRNA by G insertion occurs during mRNA synthesis via a virus-encoded activity. J Virol 64:239-246.
44. Visomirski-Robic LM, Gott JM. 1995. Accurate and efficient insertional RNA editing in isolated Physarum mitochondria. RNA 1:681-691.
45. Visomirski-Robic L, Gott JM. 1997. Insertional editing of nascent mitochondrial RNAs in Physarum. Proc Natl Acad Sci USA 94:4324-4329.
46. Volchkov VE, Becker S, Volchkova VA, Ternovoj VA, Kotov AN, Netesov SV, Klenk HD. 1996. GP mRNA of Ebola virus is edited by the Ebola virus polymerase and by T7 and vaccinia virus polymerases. Virology 214:421-430.
47. Wang D, Hawley DK. 1993. Identification of a 3′ → 5′ exonuclease activity associated with human RNA polymerase II. Proc Natl Acad Sci USA 90:843-847.