Tumor-specific synergistic therapy of mitomycin C: Modulation of bioreductive activation

Hiroshima Journal of Medical Sciences

Volumn 46, Issue 2, 1997, Pages 67-73

  Sakamoto, Noriaki ^a   Toge, Tetsuya ^a   Nishiyama, Masahiko ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Biochemical modulation; DT diaphorase; Mitomycin C; NADPH cytochrome P450

Indexed keywords

(3 IODOBENZYL)GUANIDINE; DICOUMAROL; MITOMYCIN C; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CYTOTOXICITY; DNA DAMAGE; DRUG POTENTIATION; ELECTRON; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYPERGLYCEMIA; INTRAVENOUS DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; NUDE MOUSE; TUMOR XENOGRAFT;

3-IODOBENZYLGUANIDINE; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BIOTRANSFORMATION; CELL DIVISION; DICUMAROL; DNA DAMAGE; ENZYME INHIBITORS; HUMANS; HYDROGEN-ION CONCENTRATION; IODOBENZENES; MICE; MICE, NUDE; MITOMYCIN; NAD(P)H DEHYDROGENASE (QUINONE); NADPH-FERRIHEMOPROTEIN REDUCTASE; NEOPLASMS, EXPERIMENTAL; RATS; TUMOR CELLS, CULTURED;

EID: 0030838668     PISSN: 00182052     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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