Detection of endothelin receptors in human coronary artery vascular smooth muscle cells but not endothelial cells by using electron microscope autoradiography

Journal of Cardiovascular Pharmacology

Volumn 29, Issue 6, 1997, Pages 820-826

  Russell, Fraser D ^a   Skepper, Jeremy N ^a   Davenport, Anthony P ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Autoradiography; Congestive heart failure; Coronary artery; Electron microscopy; Endothelin; Vasodilatation

Indexed keywords

ENDOTHELIN RECEPTOR; NITRIC OXIDE; PROSTACYCLIN;

ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; CELL MEMBRANE; CELLULAR DISTRIBUTION; ELECTRON MICROSCOPY; HEART TRANSPLANTATION; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION;

ADULT; AUTORADIOGRAPHY; AZEPINES; BINDING SITES; BINDING, COMPETITIVE; CORONARY VESSELS; FEMALE; HUMANS; INDOLES; MALE; MICROSCOPY, ELECTRON; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN;

EID: 0030838391     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199706000-00017     Document Type: Article

References (34)

1. Bacon CR, Cary NRB, Davenport AP. Endothelin peptide and receptors in human atherosclerotic coronary artery and aorta. Circ Res 1996;79:794-801.
2. Cohn JN. Is there a role for endothelin in the natural history of heart failure? Circulation 1996;94:604-6.
3. Cody RJ, Garrie JH, Binkley PF, Capers Q, Kelley R. Plasma endothelin correlates with the extent of pulmonary hypertension in patients with chronic congestive heart failure. Circulation 1992;85:504-9.
4. Kurihara H, Yoshizumi M, Sugiyama T, et al. The possible role of endothelin-1 in the pathogenesis of coronary vasospasm. J Cardiovasc Pharmacol 1989;13:S132-7.
5. Pacher R, Bergler-Klein J, Globits S, et al. Plasma big endothelin-1 concentrations in congestive heart failure patients with or without systemic hypertension. Am J Cardiol 1993;71:1293-9.
6. Wei C-M, Lerman A, Rodeheffer RJ, et al. Endothelin in human congestive heart failure. Circulation 1994;89:1580-6.
7. A receptor-mediated constrictor responses to endothelin peptides in human blood vessels in vitro. Br J Pharmacol 1995;115:191-7.
8. Withrington PG, de Nucci G, Vane JR. Endothelin-1 causes vaso-constriction and vasodilation in the blood perfused liver of the dog. J Cardiovasc Pharmacol 1989;13:S209-10.
9. Gardiner SM, Compton AM, Bennett T. Regional haemodynamic effects of endothelin-1 and endothelin-3 in conscious Long Evans and Brattleboro rats. Br J Pharmacol 1990;99:107-12.
10. Warner TD, Allcock GH, Corder R, Vane JR. Use of the endothelin antagonists BQ-123 and PD142893 to reveal three endothelin receptors mediating smooth muscle contraction and the release of EDRF. Br J Pharmacol 1993;110:777-82.
11. Douglas SA, Hiley CR. Endothelium-dependent vascular activities of endothelin-like peptides in the isolated superior mesenteric arterial bed of the rat. Br J Pharmacol 1990;101:81-8.
12. Bax WA, Aghai Z, van Tricht CLJ, Wassenaar C, Saxena PR. Different endothelin receptors involved in endothelin-1- and sarafotoxin S6B-induced contractions of the human isolated coronary artery. Br J Pharmacol 1994;113:1471-9.
13. Akar F, Uydes BS, Ayrancioglu K, et al. Endothelial function of human gastroepiploic artery in comparison with saphenous vein. Cardiovasc Res 1994;28:500-4.
14. Lüscher TF, Yang A, Tschudi M, et al. Interaction between endothelin-1 and endothelium-derived relaxing factor in human arteries and veins. Circ Res 1990;66:1088-94.
15. B receptors mediate contraction to endothelin-1 in human blood vessels. Circulation 1994;89:1203-8.
16. Liu JL, Chen JR, Buxton BF. Unique response of human arteries to endothelin B receptor agonist and antagonist. Clin Sci 1996;90:91-6.
17. Wagner OF, Christ G, Wojta J, et al. Polar secretion of endothelin-1 by cultured endothelial cells. J Biol Chem 1992;267:16066-8.
18. McPherson GA. A practical computer-based approach to the analysis of radioligand binding experiments. Comput Programs Biomed 1983;17:107-13.
19. Munson PJ, Rodbard D. LIGAND: a versatile computerized approach for characterization of ligand-binding systems. Anal Biochem 1980;107:220-39.
20. Bacon CR, Davenport AP. Endothelin receptors in human coronary artery and aorta. Br J Pharmacol 1996;117:986-92.
21. Caro LG, van Tubergen RP. High resolution autoradiography. I. Methods. J Cell Biol 1962;15:173-88.
22. Chun M, Liyanage UK, Lisanti MP, Lodish HF. Signal transduction of a G protein-coupled receptor in caveolae: colocalization of endothelin and its receptor with caveolin. Proc Natl Acad Sci U S A 1994;91:11728-32.
23. Tran D, Carpentier JL, Sawano F, Gorden P, Orel L. Ligands internalized through coated or noncoated invaginations follow a common intracellular pathway. Proc Natl Acad Sci U S A 1987;84:7957-61.
24. Parton RG, Joggerst B, Simons K. Regulated internalization of caveolae. J Cell Biol 1994;127:1199-215.
25. B in human kidney. Kidney Int 1993;44:36-42.
26. Russell FD, Davenport, AP. Characterization of endothelin receptors in the human pulmonary vasculature using bosentan, SB209670, and 97-139. J Cardiovasc Pharmacol 1995;26:S346-7.
27. 125I-endothelin-1 in rat kidney and lung examined by electron microscopic radioautography. Anal Embryol 1992;185:87-96.
28. B binding sites in human coronary vasculature. J Cardiovasc Pharmacol 1995;26:S351-4.
29. B receptors cause vasoconstriction of human resistance and capacitance vessels in vivo. Circulation 1995;92:357-63.
30. Ohlstein EH, Vickery L, Sauermelch C, Willette RN. Vasodilation induced by endothelin: role of EDRF and prostanoids in rat hindquarters. Am J Physiol 1990;259:H1835-41.
31. 4. Am J Physiol 1985;249:H698-702.
32. Maguire JJ, Kuc RE, Rous BA, Davenport AP. Failure of BQ123, a more potent antagonist of sarafotoxin 6b than of endothelin-1, to distinguish between these agonists in binding experiments. Br J Pharmacol 1996;118:335-42.
33. Fujitani Y, Oda K, Takimoto M, Inui T, Okada T, Urade Y. Autocrine receptors for endothelins in the primary culture of endothelial cells of human umbilical vein. FEBS Lett 1992;298:79-83.
34. A receptors in left ventricle from failing human hearts demonstrated using competition binding studies with FR139317. Br J Pharmacol 1996;117:270P.